Articles By Olga Petryna, MD
Adalimumab Induction in Early RA Yields Erosive Benefits in the OPERA Study
A number of studies have shown that the treat-to-target approach is effective in achieving clinical remission - the ultimate therapeutic goal in patients with early RA.
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Optimizing Treat-to-Target in RA
Treat-to-target is a common management strategy for rheumatoid arthritis that aims to employ the strategy most effective in terms of achievement of optimal therapeutic outcomes in RA.
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Biosimilar SB4 Performs Equally to Etanercept
Biosimilars are rapidly growing. Many of these will have their first introduction to countries outside of the USA. There is concern whether biosimilars will provide identical pharmacodynamics, biological function, efficacy and toxicity to reference products, both in the short and long term.
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Prolonged Breastfeeding Associated with Postmenopausal Osteoporosis
The effects of prior breastfeeding on bone density of postmenopausal women have been controversial. Several studies suggest that breastfeeding and childbirth lead to maternal calcium loss and a decline in bone mineral density (BMD).
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Is Early Use of TNFi in Spondyloarthritis Overkill or a Necessity?
Axial SpA (axSpA) is a chronic inflammatory disease that includes AS and non-radiographic axSpA (nr-axSpA).
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Lipid Levels and CV Events in RA
Rheumatoid arthritis not only affects the joints but can also increase risk for cardiovascular disease. The mechanism of the increased risk of cardiovascular disease in rheumatoid arthritis remains uncertain.
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Long term Denosumab Use Shows Favorable Outcomes: Results from the FREEDOM Extension Trial
Osteoporosis is a disease characterized by increased bone loss that outpaces the grown of new bone. As a result bones become less dense and more fragile and brittle; porous bones are more prone to fracture.
Read ArticleAlpha-1-Anti-Trypsin-Fc Fusion Protein Ameliorates Gouty Arthritis
Gout is the most common inflammatory arthritis affecting adults and, probably, one of the most underestimated.
Read ArticlePost-Translationally Modified Proteins as Potential New Early Arthritis Activity Markers
Defects in protein citrullination and its consequences in patients with RA have been studied widely in the recent decade. It appears that autoantibodies, including those against citrullinated proteins, are of diagnostic and prognostic relevance.
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