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covid.corona

Latest COVID-19 Numbers from CDC

d Jack Cush, MD

Following are the latest CDC numbers for COVID-19 in the U.S., including total cases and deaths; the states with the highest number of COVID-19 deaths; and COVID-19 healthcare case numbers.

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Cachexia Common in Lupus

d RheumNow

Cachexia is an underappreciated complication of systemic lupus erythematosus, researchers reported.

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Infliximab Use Near Surgery is Safe

d Jack Cush, MD

Risk factors for perioperative infections include age, comorbidity, rheumatoid arthritis and steroids to name a few; whether concurrent use of TNF inhibitor (TNFI) therapy adds to this risk has been debated. In a study of elderly patients receiving infliximab infusions, infliximab use prior to surgery did not change the risk of post-operative infections.

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DMARD Use Does Not Increase COVID Hospitalization

d Jack Cush, MD

An observational study of patients with systemic autoimmune inflammatory rheumatic diseases (AIRD) who also had COVID-19 disease shows that AIRD increased the risk of hospitalization, but that the use of disease-modifying antirheumatic drugs (DMARDs) were not associated with hospitalization.

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Secukinumab Effective in Non-Radiographic Axial SpA

d Jack Cush, MD

The PREVENT trial was a one year, phase III study that showed significant benefits when secukinumab (SEC) was given to patients with active non‐radiographic axial spondyloarthritis (nr‐axSpA) for 52 weeks.

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ACR Applauds E/M Coding Changes, Telehealth Expansion in CY 2021 Physician Fee Schedule Proposed Rule

d

The American College of Rheumatology (ACR) today applauded the Centers for Medicare and Medicaid Services (CMS) for taking steps to appropriately value cognitive care and expand telehealth access in its CY 2021 Physician Fee Schedule (PFS) Proposed Rule.

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COVID Testing study of 3046 NY Hospital employees (56% Ab testing, 20% RT-PCR, 12% both); found (9.8%) who tested positive for antibodies; Thus SARS-CoV-2 infection among Hospital workers is lower than that reported for the general public. PPE WORKS!

Dr. John Cush RheumNow ( View Tweet)

Rheum has 4 of top 10 Best Selling Blockbuster drugs of 2019: 1. Humira $21.4 billion 3. Enbrel $8.1 billion 4. Stelara $6.6 billion 10. Remicade $4.7 billion https://t.co/tE6nAdXRYS

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Life expectancy for t2009 to 2011 was 78.60 years for the total U.S. population, with the highest life expectancy for Hispanic women (84 yrs) , according to the Aug. 7 National Vital Statistics Reports https://t.co/j3THyitmie

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477 Ax-SpA pts in the CORRONA Registry finds 25% with enthesitis - those with enthesitis had worse disease activity and quality of life than those with no enthesitis. https://t.co/weQC798mck

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Dr. John Cush RheumNow ( View Tweet)

Apremilast FDA approved for Behcets in 2019 based on significant improvement in oral ulcer severity. What about genital ulcers? There was a signif improvement in QOL, but a nonsignificant trend to genital ulcer resolution (71% vs 41%) in 17 pts. https://t.co/OqDGcklyot

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Dr. John Cush RheumNow ( View Tweet)

Correlation study of MRI and OA features finds meniscal extrusion, full thickness cartilage loss and osteophytes were associated with clinical knee pain. Study of 294 OA knee patients from the Osteoarthritis Initiative (at least 4 MRI over 6 years) https://t.co/t95eGbX9iN

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Dr. John Cush RheumNow ( View Tweet)

Mortality study of 18,943 patients with PMR and 87,801 matched controls from the Clinical Practice Datalink with 8 yrs of followup finds NO increase in mortality in PMR patients adjusted MRR 1.00 [95% CI 0.97, 1.03]). https://t.co/moZwiuhOxC

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Dr. John Cush RheumNow ( View Tweet)

RheumNow Podcast - Why we Love Rheumatology Fellows (8.7.20) Watch it here>> https://t.co/ftrycqoWRR or Listen to the podcast on iTunes or on SoundCloud>> https://t.co/gi5hO0HaIl

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Dr. John Cush RheumNow ( View Tweet)

Dr. D. Minna @UTSWNews rheum grand rounds: review of OA: 1. Exercise may increase cartilage volume 2. Osteophytes are an adaptation to mechanical stimuli rather than a degen. process (no correl w/cartilage volume) 3. Hallmark of OA is abn. matrix turnover @RheumNow

k dao KDAO2011 ( View Tweet)

NIH taps Dr. Lindsey Criswell as the New Director of the National Institute of Arthritis and Musculoskeletal and Skin Diseases. She was the vice chancellor of research and a professor of rheumatology at UCSF. She begins in early 2021. Congrats!! https://t.co/H1wpYHOOWg

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Dr. John Cush RheumNow ( View Tweet)

BMS has announced deucravacitinib: the generic name for its Tyk2 inhibitor (BMS-986165) - 15 long makes it a new rheum labeling record. It's being studied in Psoriatic arthritis, psoriasis, lupus and inflammatory bowel disease. https://t.co/E2x2lelktO

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Dr. John Cush RheumNow ( View Tweet)

RheumNow Podcast - Why we Love Rheumatology Fellows (8.7.20) Watch it here>> https://t.co/ftrycqoWRR or Listen to the podcast on iTunes or on SoundCloud>> https://t.co/gi5hO0HaIl

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Dr. John Cush RheumNow ( View Tweet)

RheumNow Podcast - Why We Love Rheumatology Fellows (8-7-20) Dr. Jack Cush reviews why we all love our rheumatology fellows and our best advice for them stemming from these articles" https://t.co/7y9ap0AkdD https://t.co/LDFLQEIN4r

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Hong Kong study Myositis-specific autoantibodies in 201 pts with idiopathic inflammatory myopathies (IIM) shows MDA-5 (14%), TIFF-1γ (14%), Jo-(12.4%). MDA5 seen w/ DM, digital ulcers, amyopathy, ILD. TIF1γ was associ w/ refractory rash and cancer https://t.co/3E365F5SON

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Dr. John Cush RheumNow ( View Tweet)

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