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RheumNow Podcast – Upadacitinib FDA Approved for RA (8.23.19)
Dr. Jack Cush reports on the news and journal reports from the past week on RheumNow.com, including: how your genetics may shape your microbiome; GERD as a risk factor for TMJ?; how can MDA-5+ dermatomyositis be any worse; new drug happenings; StillsNow.com; and more.
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A Multidimensional Definition of Remission
A study from Leeds suggests 'multi-dimensional remission' (MDR) can be seen in one-third of RA patients achieving DAS28-remission; such patients have better patient-reported outcome measures, making it an optimal goal, especially from a patient's perspective.
Read ArticleOsteoporosis Tx: Good for Bones, but Not for Cutting Death Risk
Osteoporosis treatments were not linked with reduced overall mortality, according to a meta-analysis of placebo-controlled trial data.
Read ArticleGood Pregnancy Outcomes for DMARD Exposed JIA Patients
A study of pregnancy outcomes in 98 women with juvenile idiopathic arthritis (JIA) who were exposed to DMARDs shows no increased risk of major adverse pregnancy outcomes.
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Autoantibodies Don't Disappear With Remission in RA
Immunologic remission in rheumatoid arthritis, defined as the disappearance of anti-citrullinated protein antibodies and rheumatoid factor, was seen infrequently among patients achieving sustained clinical remission and did not correlate with the disappearance of symptoms, a long-term Dutch study found.
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RCT of 139 knee OA pts given either curcumin 500-mg tid or diclofenac 50-mg bid. At days 14 and 28 both had similar improvement in pain and KOOS score; but curcumin had better tolerance, less GI sxs and H2 blocker use. https://t.co/tcsDQWQOMg
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Dr. John Cush RheumNow ( View Tweet)
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Analysis of 128 Pediatric Rheum pts (JIA, FMF, etc) analzyed for reactions to 8 different biologics during 32,494 infusions/injections - the frequency of anaphylaxis (from TCZ or RTX) was 3.9% in children. https://t.co/GzvcR0R7Bv
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Dr. John Cush RheumNow ( View Tweet)
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Are you an Expert in Still's disease, Periodic Fevers, FMF or Autoinflammatory Dz? Please let me know ASAP - I want to add you to the list! https://t.co/UwKkco8q1N