Autoantibodies Don't Disappear With Remission in RA

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Immunologic remission in rheumatoid arthritis, defined as the disappearance of anti-citrullinated protein antibodies and rheumatoid factor, was seen infrequently among patients achieving sustained clinical remission and did not correlate with the disappearance of symptoms, a long-term Dutch study found.

Skyrizi Outduels Humira in Psoriasis

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A head-to-head trial has shown that risankizumab was significantly superior to adalimumab in providing skin clearance (PASI90) in patients with moderate-to-severe plaque psoriasis, with no difference in safety signals between the two agents.

Upadacitinib (RINVOQ) FDA Approved for Rheumatoid Arthritis

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The US Food and Drug Administration (FDA) on Friday, August 16, approved AbbVie JAK1 inhibitor, Rinvoq (upadacitinib) for adults with  rheumatoid arthritis with moderately to severely active disease either not responding to, or intolerant of, methotrexate (MTX). 

RheumNow Podcast – Antibiotics Increase RA Risk (8.16.19)

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Dr. Jack Cush reports the news and important journal articles from the past week on RheumNow.com.

Updated CDC Recommendation for Serologic Diagnosis of Lyme Disease

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Serologic testing is the principal means of laboratory diagnosis of Lyme disease. Current recommendations include using a sensitive enzyme immunoassay (EIA) or immunofluorescence assay, followed by a western immunoblot assay for specimens yielding positive or equivocal results.

On July 29, 2019, the Food and Drug Administration cleared several Lyme disease serologic assays with new indications for use, allowing for an EIA rather than western immunoblot assay as the second test in a Lyme disease testing algorithm. Thus, serologic assays that utilize a second EIA in place of western immunoblot assay are acceptable alternatives for the serologic diagnosis of Lyme disease.

Rise in Fatty Liver Disease Linked to Obesity and Diabetes

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Gut has published population results from NHANES population study showing that the prevalence of fatty liver disease is rising in the US and is driven by obesity and diabetes.

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Are you an Expert in Dx & management of Still's disease, Periodic Fevers, FMF or Autoinflammatory Dz? If so -- please Direct Message me and tell me where you are and who you want to see (Im developing an EXPERT Referral list). OR TELL ME who is person to see in your town! https://t.co/BGBRbn4yko