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Abstr#0846 @RheumNow #acr19 #acrbest
Eval of MACE and VTE of UPA based on phs 3 trials: 1. NO ⬆️risk MACE/VTE over 2 yrs compared to MTX, ADA
2. NO correl. w/lipid levels, dose of drug with MACE/VTE and UPA.
* despite the safety seen, UPA’s label still include VTE risk https://t.co/unOBvoW8Ub
k dao KDAO2011 ( View Tweet)
#ACR19 @ElenaNikiUK @RheumatologyUK vaccination: Calabrese suggests we should be more didactic in telling our patients to get the flu and shingles vaccines. I can see a clinic notice going up when I get home!
John Axford ProfAxford ( View Tweet)
Nintedanib brought modest benefit to IPF & SSc-ILD, but now ILD in other autoimmune dx as well?
Small but real diff in lung volumes, no diff in QOL or acute exac/deaths, diarrhea but largely not limiting in study. Works in absence of alt, but worth it?
#ACR19 ABST0374 @RheumNow https://t.co/1CDTgiQkMd
David Liew drdavidliew ( View Tweet)
After rituximab use, patients with ANCA-associated vasculitis had increased rates of hypogammaglobulinemia, as compared to patients with RA or CTD. Prednisone>10mg/day may in part account for this association. Dr. Stefanie Wade #ACR19 @rheumnow #Abstr #ACRBest https://t.co/CPWN2qSI9t
Jonathan Hausmann MD hausmannMD ( View Tweet)
Ileal but not colonic inflammatory gut lesions are linked to more fatty lesions on MRI-SIJ in newly diagnosed SpA patients. Baseline microscopic gut inflammation was not associated with erosions, sclerosis nor ankylosis. DeCraemer et al #ACR19 @RheumNow #axialspondyloarthritis
Dr. Antoni Chan synovialjoints ( View Tweet)
In early axSpA, inflammation in one SIJ quadrant leads to structural damage in the same quadrant. Rodrigues-Manaca #ACR19 @RheumNow #axialspondyloarthritis
Dr. Antoni Chan synovialjoints ( View Tweet)
“These drugs aren’t going anywhere because they are literally curing cancer.” - Dr. Susan Manzi on checkpoint inhibitors and autoimmune adverse events. Check out the poster hall to see all the emerging immune related AEs. #ACR19 @RheumNow
Maeve Gamble MaeveGamble ( View Tweet)
ACOG recommends low dose ASA for all pregnant women with lupus. But we’re not doing well...in a multi-national SLE cohort of 475 pts, only 25% were exposed to ASA. #ACR19 @RheumNow #lupus
Maeve Gamble MaeveGamble ( View Tweet)
Abstr#808 Pt2 of GiACTA:
*42% of pts in remission and on no tx after 1 yr of wkly TCZ maintained tx free remission for 2 more yrs
*GCSs over 3yrs lower in pts originally assigned TCZ
*For flares, reinitiating TCZ restored remission
*No new safety signals
#ACR19 @RheumNow #GCA
Maeve Gamble MaeveGamble ( View Tweet)
What do you do with residual fatigue in well controlled RA? #ACR @RheumNow Abstr#461now
Janet Pope Janetbirdope ( View Tweet)
Fatigue is a big deal for pts with ERA but if rapid remission by 3 months fatigue improvement is better and differences persist for 5 years but mean fatigue is not normal #ACR19 @RheumNow abstr#461 https://t.co/hDbPmCql1m
Janet Pope Janetbirdope ( View Tweet)
I didn’t realize how fast Pegloticase works.
Assuming the urate burden of a gout patient, Pegloticase can degrade all the urate in the body over 5-40 days!
#ACR19 @rheumnow 3S050 Lipsky
Dr Irwin Lim _connectedcare ( View Tweet)
Evidence based non-pharm therapy #ACR19 #fibromyalgia @RheumNow FM MTP Clauw https://t.co/ZhGLsqg0Tb
Philip Robinson philipcrobinson ( View Tweet)
Mean time to total resolution of all tophi was 9.9 months on Pegloticase
- velocity of resolution was very heterogenous
#ACR19 @rheumnow 3S050
Dr Irwin Lim _connectedcare ( View Tweet)
Dr. Weinblatt’s vaccine review slide. @RheumNow #ACRbest #ACR19 https://t.co/rKShBbdk7z
Dr. Rachel Tate uptoTate ( View Tweet)
Pneumonia vaccination update! #ACR19 @RheumNow https://t.co/yJVg4wt90S
Dr. Rachel Tate uptoTate ( View Tweet)
Reductions in mean arterial pressure, systolic & diastolic BP in responders to biweekly Pegloticase
Not associated with any changes in renal function. Independent of any effect XaNthine Oxidase
#ACR19 @rheumnow 3S050
Dr Irwin Lim _connectedcare ( View Tweet)
Prednisone at 5mg po daily for over three months is a FRAX risk factor we need to remember. Knowledge bowl pearls. @RheumNow #ACR19
Dr. Rachel Tate uptoTate ( View Tweet)
Uveitis is associated with bisphosphonates. Calcium citrate is useful in pts with history of renal calculi. Knowledge bowl pearls. #ACR19 @RheumNow
Dr. Rachel Tate uptoTate ( View Tweet)
Almost all patients with pain have mixed pain states, so working out effective therapies for their pain depends on the proportion of each type of pain they have: nociceptive/neuropathic/centralised pain #ACR19 FM MTP Prof Clauw @RheumNow
Philip Robinson philipcrobinson ( View Tweet)
