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The Cartel is Coming for Rheumatology

Eric Dein, MD

"What Do Blockbuster Drugs & The Black Market All Have in Common?" asked Dr. Madelaine Feldman at RheumNow Live 2025. They thrive, she explained, on market exclusivity "... until they don't." At first glance, the pharmaceutical marketplace may not appear like a crime drug ring, but Dr. Feldman of Tulane University described how sinister forces of market manipulation have negatively impacted patient care for years.

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Valentine RNL 2025 Review (2.14.2025)

Jack Cush, MD

Dr. Jack Cush reviews highlights from RheumNow Live 2025 held in Dallas, TX on Feb. 8-9, 2025.

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Drug Naming Games (2.7.2025)

Jack Cush, MD

Dr. Jack Cush reviews the news, regulatory and journal reports from the past week on RheumNow.com.

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Young Males and Future Risk of MSK and Chronic Diseases

Jack Cush, MD

A large cohort of 18-year-old Swedish males were followed longitudinally for cardiovascular, respiratory, and musculoskeletal outcomes.

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Infectious Sacroiliitis

Jack Cush, MD

A large Chinese cohort study of patients with infectious sacroiliitis (SI) suggests that CT-guided biopsy of the sacroiliac joint is necessary to properly identify the infectious pathogen leading to SI.

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Adalimumab Withdrawal in Uveitis Patients

Jack Cush, MD

Adalimumab is an effective treatment for JIA-associated uveitis and has been FDA approved for such use - but for how long and can the drug be withdrawn? An adalimumab (ADA) withdrawal trial has shown recurrence of uveitis, arthritis, or both, when the disease was previously controlled on ADA.

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Weak Data (1.24.2025)

Jack Cush, MD

Dr. Jack Cush reviews the news and journal reports from RheumNow.com, and features Dr. Charity Dean, the Keynote speaker at RheumNow Live 2025, and why she is an inspiration.

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Janet Pope @Janetbirdope #Disease #activity in #axSpA #ASDAS - a crude measure of activity in #ankylosing #spondylitis Is related to #radiographic #progression 👇 ⬆️ CRP May be more predictive #ClinicalPearl⁩ #RNL2025 https://t.co/34wrMuz9mO
Dr. John Cush RheumNow ( View Tweet)
Full read, comprehensive review of Hidradenitis Supprativa in Lancet Feb 1, 2025 Common assn; DM, IBD, Smoking, Obesity, metabolic syndr, NASH, SpA, RA FDA approved Rx: Adalimumab, Secukinumab, Bimekizumab https://t.co/5Tb8on21E0 https://t.co/BLu6Zaejj5

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Dr. John Cush RheumNow ( View Tweet)
“Preventing” Arthritis in Psoriasis Prevention of the development of our systemic rheumatic diseases in individuals deemed at risk, or with some form of precursor disease process, has been a hot topic in recent years. https://t.co/nGKGUkKVUl https://t.co/PruJZLAq9n

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Dr. John Cush RheumNow ( View Tweet)
🆕 slide from @Official_ASAS HLA-B27 strongly associated with Anterior #Uveitis in #SpA #AAU #AxSpA #B27 https://t.co/lq19vIys9x

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Dr Gurdeep S Dulay gurdeep_dulay ( View Tweet)
1/3 of #axial #PsA 👇 No #SI joint changes , only #axial ⁦@RheumNow⁩ #RNL2025 Catherine Blackwell #ClinicalPearl https://t.co/YmoipL1bME

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Janet Pope Janetbirdope ( View Tweet)
Pregnancy is 🔥 inflammatory Hard to interpret MRI of SI joints in setting of pregnancy Ideally, don't score MRI during pregnancy or 1 year afterwards, would be affected by the pregnancy If needed for clinical eval, focus on structural lesions like erosions #RNL2025 @RheumNow

Eric Dein ericdeinmd ( View Tweet)

Infectious Sacroiliitis A large Chinese cohort study of patients with infectious sacroiliitis (SI) suggests that CT-guided biopsy of the sacroiliac joint is necessary to properly identify the infectious pathogen leading to SI. https://t.co/GYI8iz0rOS https://t.co/3wQR47Wd4g

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Dr. John Cush RheumNow ( View Tweet)
Korean Biologics (KOBIO) registry showed SpA pts have higher risk of infection. 2,129 AS pts (7108 PY FU) most common was respiratory infx (26/1000 PY), followed by herpes zoster (6/1000 PY) Risk includes age, ischemic CV Dz, diabetes, CKD, peripheral arthritis.… https://t.co/0j1fH7OymW https://t.co/gqa1csylsn
Dr. John Cush RheumNow ( View Tweet)
Korean population-based study shows that from 2010 to 2023 prevalence of ank Spondylitis (AS) increased 27 per 100,000 (2010) to 82 per 100,000 (2023). Also increasing were # of pts >50 yrs (20-33%), #females (18-24%), Comorbidities, TNFi use (30-43%), while csDMARDs declined.… https://t.co/9NjU1IugaF https://t.co/kTCtIj2BjD
Dr. John Cush RheumNow ( View Tweet)
A substantial # of pts with inflammatory arthritis (IA) are not receiving adequate treatment for depression and anxiety(same as those IA-free controls). Canadian study of 6,951 w/ IA & depression, on 50% recv treatment & 20% psych. Rx for depression. Similar for 3,701 w/ IA &… https://t.co/CfpwEtLH3c

Dr. John Cush RheumNow ( View Tweet)

Just published, a new review of Axial spondyloarthritis from Baraliakos, et al in Lancet! https://t.co/0pIFM1Q2jO https://t.co/iGQ3ES7Nie

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Dr. John Cush RheumNow ( View Tweet)
QD Clinic - Acute Neck & Back Pain Acute onset febrile, polyarthritis, neck and low back pain Features Dr. Jack Cush. QD Clinics - lessons from the clinic, sponsored by RNL2025 in Dallas, TX; Feb 8 & 9, 2025 Register at https://t.co/2dcFVgu8z6 https://t.co/2GqyqXAjbF https://t.co/vIeqdHyayV

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Dr. John Cush RheumNow ( View Tweet)
Just published, a new review of Axial spondyloarthritis from Baraliakos, et al in Lancet! https://t.co/AuMTLo8iQO https://t.co/1icGoXKfB9

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Dr. John Cush RheumNow ( View Tweet)
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