All News
RESTORE trial: yet another failure for PRP injections for knee #OA. Study of 288 Knee oA over 50 years - knee pain scores of −2.1 vs −1.8 on an 11-point scale (range, 0-10) and no difference between PRP and PBO at 12 moshttps://bit.ly/3pqldWU
Dr. John Cush RheumNow ( View Tweet)
Best of 2021: EULAR Guidelines on Intraarticular Therapy
EULAR has published evidence-based recommendations on the use of intra-articular therapies (IAT) based on the literature review and recommendations of a multidisciplinary international task force. These IAT recommendations apply to adult patients with peripheral arthropathies.
Read Article
Metanalysis of 11 studies, 46 819 participants shows low quality evidence that knee extensor muscle weakness is assoc w/ increased the odds of knee osteoarthritis in women (OR 1.85)and men (OR 1.43); also radiographic knee OA https://t.co/Md7eODvsIy
Links:
Dr. John Cush RheumNow ( View Tweet)
NYC Hosp for Special Surgery is the 1st to use a "smart" knee arthroplasty - TKR with a smart sensor capable of monitoring steps, speed, range of motion & other knee functions fed back to the orthopedist = called Persona IQ, FDA authorized https://t.co/QR49JC7oCz
Links:
Dr. John Cush RheumNow ( View Tweet)
What are the advantages and disadvantages of #ultrasound-guided intra-articular injections? Check out this slide👇from Lt.Col/Dr. Arjun's lecture:
#iracon21 #IRACON2021 @2021Iracon @APLAR_org #mskus #rheumatology https://t.co/mhq9OgBk7a
sheila RHEUMarampa ( View Tweet)
Telehealth Diet and Exercise Benefits Knee Osteoarthritis
Annals of Internal Medicine has reported the results of a randomized clinical trial showing that telehealth-delivered exercise and diet programs improved pain and function in knee osteoarthritis patients who were overweight. While both were beneficial, exercise had a greater effect than die
Read Article
CBD in Hand OA and PsA: Dr. Richard Conway ( @RichardPAConway) reviews abstract #1456 presented at the #ACR21 annual meeting.
https://t.co/o3jMFMMgZF
Links:
Dr. John Cush RheumNow ( View Tweet)
Geriatric Rheumatology:Improving care of aging patients
Dr.Kathryn Dao ( @KDAO2011) moderates a panel w/ Drs.Una Makris, Katherine Wysham, Sebastian Sattui + Devyani Misra, as they discuss aspects of improving care of/outcomes for aging patients. #ACR21
https://t.co/lF3yUZBEkd https://t.co/hYufA8ptqj
Links:
Dr. John Cush RheumNow ( View Tweet)
Targeting the HUGE dilemma!🎯
#Psoriatic vs Erosive #OA
PsA
👉 Fluffy bone formation(enthesitis of phalanges)
👉 Marginal erosions(vs central)
👉 Many jts in same digit(ray inv)
👉 Periarticular SOFT tissue swelling (dactylitis).
👉 NOT much hand OA
#ACR21 RadiologyBootCamp https://t.co/OQLPoeRLny
Ashima Makol MD AshimaMakol ( View Tweet)
Live from #ACR21:
Learning about osteoarthritis from Dr. Marc Hochberg.
"Don't use the term degenerative joint disease."
-much more involved.
I like this figure of the multiple different phenotypes.
#ACRAmbassador https://t.co/UwU4vCmYXa
Jilaine Bolek Berquist BolekBerqui ( View Tweet)
OA oral session - abstract 1904
Devin Driscoll (mentor @tuhina_neogi) presenting data from MOST:
Evaluation of Neuropathic-like Symptoms and Objective Signs of Neuropathy Post-Knee Replacement
#ACR21 https://t.co/APZAJdHH5M
Rheum Cat rheum_cat ( View Tweet)
Quick plug:
not all joint pain in ICI-treated pts needs reflex steroids
eg OA can get exacerbated by ICI Rx
(ICI-aOA)
call rheum, hold the PNL & save tumor response
@ReidMDMPH @got_rheum @lovetolearn27 +me
#ACR21 ABST1518 @RheumNow
our paper @jitcancer https://t.co/InespbOn6m https://t.co/HSjtGrwePE
David Liew drdavidliew ( View Tweet)
Watch my video of #ACR21 Abstract 1456, a double blind RCT of CBD for hand OA and PsA @RheumNow https://t.co/p0IiYzYe2m
Richard Conway RichardPAConway ( View Tweet)
My video comment on the cannabidiol (CBD) double-blinded RCT in hand OA/inactive PsA #ACR21 for @RheumNow
Great work by @Joner_MD et al
& kudos to funders @PsoriasisDK @Gigtforeningen @AalborgUH @aalborguni giving us data to answer a question often asked
https://t.co/e0mO0SriUu https://t.co/9DveN4jLls
David Liew drdavidliew ( View Tweet)
My video comment on the cannabidiol (CBD) double-blinded RCT in hand OA/inactive PsA #ACR21 for @RheumNow
Great work by @Joner_MD et al
& kudos to funders @PsoriasisDK @Gigtforeningen @AalborgUH @aalborguni giving us data to answer a question often asked
https://t.co/e0mO0SriUu https://t.co/9DveN4jLls
David Liew drdavidliew ( View Tweet)
Interesting results where cannabidiol NEG results in RCT in hand OA and PsA. ? Throw out the ‘pot’with the dish water? Did it stimulate appetites? Was pain the same but interference less? Abst#1456 #ACR21 @RheumNow https://t.co/rnz82Paxkr
Janet Pope Janetbirdope ( View Tweet)
CBD for pain in hand OA/inactive PsA:
- works in animal models (many things do)
- other neg RCTs didn't use CBD itself
- DBRCT: 12w continuous, n=136, min dropout
Result:
does absolutely nothing
I bet big money it will be tried again & again
@Joner_MD #ACR21 ABST1456 @RheumNow https://t.co/lZLVrgrKST
David Liew drdavidliew ( View Tweet)
If you need a #knee replacement move out of Ontario. More income disparity of access to #TKR in Ontario vs Pennsylvania. Lack of universal #healthcare in 🇨🇦. Oh Canada we fail. @RheumNow #ACR21 abst#1037 https://t.co/kobUlT3Ugr
Janet Pope Janetbirdope ( View Tweet)
Oral Calcitonin not recommended for OA - studies did not show efficacy
Strontium Ranelate study below was considered a positive study in KOA with efficacy but had Cardiovascular toxicity - now off the market. https://t.co/gcYH9xoxeo
Bella Mehta bella_mehta ( View Tweet)
Cathepsin K - has some promise in Knee OA - now going to Phase 3
@RheumNow https://t.co/exUFqcCJy1
Bella Mehta bella_mehta ( View Tweet)