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Do you need to pulse steroids in GCA? ACR 2022 abstract#0459 data says oral only may be sufficient Oral vs IV MP - p=0.621 Still favor IV in severe cases @philseo #RNL2024 @RheumNow

Eric Dein ericdeinmd ( View Tweet)

Amaurosis fugax is not the only vision symptoms to assess in patients with #GCA. Blue vision, double vision (if patients have to look at you in a side gaze prevent double vision) may also be present - Dr. P Seo @rheumnow #RNL2024 https://t.co/AhQnOJF7fa

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TheDaoIndex KDAO2011 ( View Tweet)
#RNL2024 @RheumNow @philseo: I now give Tociliizumab for nearly all patients with GCA GiACTA shows we weren't doing well enough with steroid monotherapy GiACTA shows dosing frequency does not make a big difference in new diagnosis, but makes a difference in relapsing disease https://t.co/JBgUQtZSAr

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Eric Dein ericdeinmd ( View Tweet)
When thinking of GCA there are only 2 questions you need to ask. Dr. @philseo reminds us to 1. Establish if new or recurrent disease 2. Assess for presence of visual symptoms #RNL2024 @RheumNow https://t.co/MGML3EafPu

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Dr. Rachel Tate uptoTate ( View Tweet)
How I do it, treatment of CGA with Dr. @philseo, who thoughtfully paused so everyone could take a picture of this slide knowing full well it was already at our fingertips! Such a gentleman! #RNL2024 @RheumNow https://t.co/8kqacqkRM6

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Dr. Rachel Tate uptoTate ( View Tweet)
Dr. Phillip Seo contemplates if Taylor and Travis had vasculitis, surely the dose for each would not be the same. Wish you were here @rheum_cat to weigh in on this. #RNL2024 @rheumnow https://t.co/1ynctgIknx

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TheDaoIndex KDAO2011 ( View Tweet)
In case you needed any more reasons why @philseo is the best @rheum_cat , this is his first slide @RheumNow #RNL2024 https://t.co/Ar0v7sQuuX

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Richard Conway RichardPAConway ( View Tweet)
Dr @anisha_dua's takehome points for treating GPA in 2024 *RTX and CYC are both effective followed by RTX at least 500mg q 6 mo for at least 2 years *PLEX not generally used, but may be effective in preventing ESKD *Rapid GC tapering may not be suitable for all pts *Avacopan is… https://t.co/haI19Sgpmu https://t.co/jhjXLwd0Uw

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Dr. Rachel Tate uptoTate ( View Tweet)
PJP prophylaxis in GPA. Always a trade off but these things are not created equal. PJP or sepsis are much worse on average than the AEs @anisha_dua @RheumNow #RNL2024 https://t.co/9sECd7fSRk

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Richard Conway RichardPAConway ( View Tweet)
Remission maintenance in AAV. First 2 years is clear - fixed dose RTX is superior. After that it is clear that following ANCA is suboptimal, could consider either B-cell return dosing or ongoing fixed dosing @anisha_dua @RheumNow #RNL2024 https://t.co/0Elir88L9U

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Richard Conway RichardPAConway ( View Tweet)
Maintenance issues in GPA. Clear messages. 1. RTX is best 2. Fixed 6-monthly RTX best for 1st 2 years. 3. Don't stop RTX at 2 years! @anisha_dua @RheumNow #RNL2024 https://t.co/jS3jWm0CcS

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Richard Conway RichardPAConway ( View Tweet)
The answer to "always" is "always" no, correct? PEXIVAS low dose is a great baseline plan, but always adjust in light of the individual patient both upfront and especially if things aren't working out @anisha_dua @RheumNow #RNL2024 https://t.co/RPnpAdB1eG

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Richard Conway RichardPAConway ( View Tweet)
Rapid GC taper in ANCA vasculitis #RNL2024 @RheumNow @anisha_dua PEXIVAS - reduced GC is safe, decreased ifns Retrospective real world - 234 pts. Reduced dose GC+RTX increased death/ESKD HR 2.42. No difference in infections https://t.co/SWIUSyVbWb

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Eric Dein ericdeinmd ( View Tweet)
Great talk @anisha_dua re:AAV, solid updates on mgmt decisions Looking forward to debating this study with @lastwalsh w/@MatsJunek moderating... @TerrierBen any updates on when your RWD study will be published? @RheumNow https://t.co/ywVaOIp2WJ

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Mike Putman EBRheum ( View Tweet)
Contrasing ACR/VF and EULAR GPA guidelines from @anisha_dua @RheumNow #RNL2024 https://t.co/RLJx9fJHGk

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Richard Conway RichardPAConway ( View Tweet)
"Real world studies: When people stop being polite and start getting real." Dr @anisha_dua #RNL2024 Comparing Walsh to Nagle in terms of primary outcomes, regimens, pt populations, and plasma exchange. @RheumNow https://t.co/io8OGnWxdS

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Dr. Rachel Tate uptoTate ( View Tweet)
Is there data for PLEX in GPA? @anisha_dua #RNL2024 @RheumNow PEXIVAS negative study But subgroups show decreased dialysis... But, no improvement in mortality and increased infection risk https://t.co/K9VbcNNsge

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Eric Dein ericdeinmd ( View Tweet)
#RNL2024 @RheumNow @anisha_dua Throwing the kitchen sink in severe GPA CYC + RTX combo - sick population (median GFR 9, 47% on HD, 52% DAH, all received PLEX too) - 85% survival, 69% not ESKD, low rates of relapse (13% at 36 mos) But, prolonged B cell depletion, aggressive Rx https://t.co/9AZFMQ3o9P

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Eric Dein ericdeinmd ( View Tweet)
#RNL2024 is up and at ‘em this Sunday morning! ⁦@RheumNow⁩ ⁦@KDAO2011⁩ ⁦@RichardPAConway⁩ ⁦@ericdeinmd⁩ https://t.co/AtL9QiRnW4

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Dr. Rachel Tate uptoTate ( View Tweet)
@anisha_dua reviews differences between EULAR vs ACR Vasculitis guidelines #RNL2024 @RheumNow https://t.co/1aIbnX5KBI

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TheDaoIndex KDAO2011 ( View Tweet)
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