RheumNow Podcast – Take it Back Jack! (4.26.19)

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Dr. Jack Cush reviews the news and journal articles from the past week on RheumNow.com

Statins in RA Patients Without CVD: Nonsignificant Results

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Patients with RA, but without CV disease, who were treated with atorvastatin appeared to experience cardiovascular (CV) benefits similar to what has been observed in other populations, with a risk reduction of approximately one-third, according to a large, but prematurely terminated, trial in the

Polypharmacy Blunts Responses and Ups the Safety Risks

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A study from the British Society for Rheumatology Biologics Register (BSRBR-RA) demonstrates that polypharmacy is a predictor of lower treatment responses and more serious adverse events (SAEs) in rheumatoid arthritis (RA) patients.

Intraarticular Trans-Capsaicin Effective in Knee OA

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A novel study has shown that intraarticular therapy with high‐purity synthetic trans‐capsaicin (CNTX‐4975) for chronic knee osteoarthritis (KOA) was associated with significant relief of knee pain.

Smoking Not Protective Against Knee OA

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Researchers found no protective effect of smoking against knee osteoarthritis (OA), according to a new longitudinal cohort study of 620 individuals with meniscal tears treated at five sites in Denmark.

Dr. Harold E. Paulus (1929-2019)

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Dr. Harold “Hal” Paulus lives in the annals of Rheumatology as a major contributor, mentor, researcher and clinical trialist. He passed away last week, one day after his 89th birthday. I met Dr. Paulus as a fellow in 1985, when he easily included me in his discussions and research on rheumatoid arthritis. I admired his easy demeanor, wry humor and every man character. Most remark on his calm recessive and kind personality that was complemented by a body of work that was large, impactful and usually at the cutting edge.

Many of Dr. Paulus’ colleagues and friends have contributed their testimonies and fond memories of this great man.

An Autoimmune Diagnosis Alters Perceptions of Pregnancy and Lactation

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A study from UT Southwestern and the Baylor Research Institute examined the preceptions and practices of women with autoimmune or inflammatory rheumatic diseases (AIRD) noting that an AIRD diagnosis changed most womens future hopes and plans regarding pregnancy and lactation.

FDA Approves Romosuzumab (Evenity) for High Risk Osteoporosis

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The US Food and Drug Administration today approved Evenity (romosozumab-aqqg) to treat osteoporosis in postmenopausal women at high risk of osteoporotic fracture, including those with a history of osteoporotic fracture or multiple risk factors for fracture, or those who have failed or are intoler

Increasing Prevalence and Consequences of Interstitial Lung Disease in RA

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Interstitial lung disease (ILD) has been a hot topic in numerous journals recently with reports of increasing incidence and links to disease activity.

RheumNowLive On Demand: MTX Impact in RA - Dr. Michael Weinblatt

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A clip from RheumNow Live On Demand. You can access the full library of content from the meeting.

RheumNowLive On Demand: Pre-Clinical RA - Dr. Michael Holers

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A clip from RheumNow Live On Demand. You can access the full library of content from the meeting.

RheumNow Podcast – Loretta Lynn Arthritis (3.29.19)

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Dr. Jack Cush reviews the news and journal reports from the past week on RheumNow.com.

For RA With COPD, Abatacept is Safe

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Patients with rheumatoid arthritis (RA) who also had chronic obstructive pulmonary disease (COPD) had no increased risk of serious respiratory complications when treated with abatacept (Orencia), a large claims-based analysis found.

Best of 2019 - Ups and Downs with Abatacept

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Two recent studies have examined the effect of starting abatacept upon the risk of serious hospitalized infections or cancer, showing divergent results from claims data analyses.

Artificial Intelligence to Predict Rheumatoid Disease Activity

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A recent study in JAMA Network Open shows that artificial intelligence models can use electronic health record data to prognosticate future patient outcomes in rheumatoid arthritis (RA).

CRA Position Statement on Medical Cannabis Use

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Courtesy of the Canadian Rheumatology Association (CRA) website, here are consensus guidelines on medical cannabis use.

Rheumatology patients experience prevalent pain that is only modestly controlled with current treatment strategies.

RheumNow Podcast – You Owe Me a DEXA (3.15.19)

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Dr. Jack Cush reviews this week's news and highlights from RheumNow.com.

First Line IL-1 Inhibition in Systemic JIA

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First-line treatment of systemic juvenile idiopathic arthritis (JIA) with anakinra (Kineret) was highly effective as monotherapy, minimizing the need for glucocorticoids, a single-center prospective study found.

Multiple Delays in Referral of New RA Patients

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A UK study of early onset arthritis or new rheumatoid arthritis patients shows multiple sources of delayed referral to the first rheumatology consultation.

Biologic Agents have Equal Efficacy in Enthesitis and Dactylitis

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A systematic review has shown that TNF inhibitors (TNFi) are equaled in efficacy by other biologic agents (ustekinumab, secukinumab, and ixekizumab) in psoriatic arthritis (PsA) patients with in dactylitis and enthesitis.