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Here are my highlights from day three, Sunday, of the ACR 2020 Convergence.
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Eric Dein
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Draft #ACR20 Rx Recommendations for RA: MTX monotherapy conditionally rec over csDMARD dual or triple Rx, MTX+TNFi @RheumNow https://t.co/jyjRD5aadN
Mrinalini Dey
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Prelim. results: Immunogenicity of adjuvanted #HerpesZoster subunit #vaccine in #RheumatoidArthritis patients taking #JAKinhibitors
- Most RA pts on JAKi have sufficient antibody response to HZ vaccine
- Acceptable safety profile
Abs#1997 #ACR20 @RheumNow
https://t.co/8HWAIwOATD
Meral K. El Ramahi, MD
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Checkout this session live now for an update on RA treatment guidelines (last updated in 2015)! #ACR20 @RheumNow https://t.co/Y4Ax3E4OHb
Meral K. El Ramahi, MD
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Poll results are in! 50% of those that responded note that they recommend breathing exercises, yoga, and increase dietary intake of turmeric and ginger to their RA patients! #ACR20 @RheumNow https://t.co/04vOUOzRtj
Meral K. El Ramahi, MD
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Poll results are in! 48% of those that responded are not yet convinced of the benefits of omega-3 fish oil supplements in pts w/ RA! #ACR20 @RheumNow https://t.co/B6f8ecWj07
Meral K. El Ramahi, MD
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A large observat study showed no difference in risk of major CV events in RA pts that were newly started on either MTX or HCQ. A greater stroke risk but lower risk of MI & hospitalized HF was seen in MTX initiators. #Abst1993 #ACR20 @RheumNow
Richard Conway
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Dr Kaellmark reports on immunogenicity of adjuvant herpes zoster subunit vaccine in RA patients treated with JAKi. 40 RA patients and 20 controls. Satisfactory serological responses and tolerability seen. @rheumnow #ACR20 Abstr#1997 https://t.co/UlDe4NllU0
Dr. John Cush
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Abatacept in RA and ILD Patients: Dr Richard Conway (@RichardPAConway) #ACR20
https://t.co/e31VsnXFq5 https://t.co/sCrqLtXFFc
Janet Pope
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IA steroids for knee OA did NOT ^ X-ray progression to TKR vs IA Hyaluronic acid! Data from 2 cohorts, n=792 knees. Similar X-rays for single & multiple injections of either Rx. Not Randomized but helpful! Abstr#1652 @RheumNow #ACR20 @CRASCRRheum https://t.co/1yzr5QkIzV
Dr. Rachel Tate
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New PT-CDAI showed agreement w/ MD(DO)-CDAI at id-ing active vs. controlled RA. Results suggest that PT-based swollen joints were more c/w physician assessments than PT tender joint counts. Useful for telemed! #ACR20 @RheumNow @Janetbirdope #ABS0483 https://t.co/tozp9qBRXT
Richard Conway
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Dr Castillo-Bustamante presents a human otopathological study demonstrating RA involvement of ossicular joints of middle ear. Is there a functional effect on hearing? @rheumnow @bososhea #ACR20 Abstr#1759 https://t.co/iWlKs2KdOW
Eric Dein
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There is hope for RA fatigue - improvements seen in F sex, non-smokers, lack of depression, high baseline fatigue. Abst#1737 @RheumNow #ACR20. Interested in role of exercise in the study. Smoking is BIG cause of fatigue, must address with fatigued RA pts.
Richard Conway
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Dr Winthrop reports on rates of influenza in RA in tofactinib clinical programme over 14-15 seasons. No significant differences in rates between tofa, ADA, MTX, and placebo. @rheumnow #ACR20 Abstr#L04 https://t.co/8RrG0I2Zwm
Dr. John Cush
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Kaleb Michauds study from the RA FORWARD registry shows, during the pandemic, significant medication changes (w/o MD consult) or appts. These observations show we were not prepared for this and that Rx suffered. #ACR20 Abstr#L05 https://t.co/vrDd0myGos https://t.co/JFUXItVdRQ
Richard Conway
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Dr Bergman reports on PROs in RCT of upadacitinib versus abatacept in bDMARD-IR RA patients. Greater improvement in PROs with upadacitinib especially in physical functioning, pain, and general health @rheumnow #ACR20 Abstr#1728 https://t.co/NWKrhYAfZn
Dr. John Cush
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Smartphone T2T management of RA & SLE is possible. With over 127,316 DAS28 & 42,593 SLEDAI assessments over 2 yrs. T2T was lowest in spring for both, correlating w/ holidays in China. #ACR20 Abstr#1018 https://t.co/bGJtSTDqzo https://t.co/34za6kokOp
Eric Dein
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SELECT-CHOICE on UPA vs ABA in RA in NEJM Oct 2020. How about PROs? UPA wins in phys fxn, pain, general health over ABA. Abst#1728 @RheumNow #ACR20. ABA better if a safety concern, but this is more evid to go for UPA
sheila
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#mskus findings in pt w/normal muscle volume(ABC) vs. w/sarcopenia(DEF).
This Japanese study showed US of VL muscle is useful in discriminating RA pts w & w/o sarcopenia. @RheumNow #ACR20 abs1537 https://t.co/Gv7V0eebEt
sheila
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Accdg to this study, no association was found between IFN levels and cognitive function in SLE pts (even after considering factors like SLE dse duration)
Interesting! @RheumNow #ACR20 abs1788 @ZahiTouma https://t.co/F4j8H1CWJ9
