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Hand OA and Heroes in Rheumatology (2.11.2022)

Jack Cush, MD

Interesting reports this week about dementia, who gets hand OA and a great list of women Heroes and Pillars of Rheumatology. Tune in as Dr. Jack Cush reviews the news and journal articles from this past week in RheumNow.com.

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Hand Pain Related to Obesity and Inflammatory Markers

Jack Cush, MD

Arthritis & Rheumatology has published the results of the Nor-Hand study, showing that pain hand osteoarthritis (OA) was related to a higher body mass index (BMI) and also to inflammatory adipokines, such as leptin.

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Why Would Hand OA Be Less Severe in Black People?

MedPage Today

Osteoarthritis (OA) of the hand was less severe according to objective and pain-related markers in Black patients versus those of other racial/ethnic groups after adjustment for known risk factors, researchers found.

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An Ounce of Prevention (2.4.2022)

Jack Cush, MD

Dr. Jack Cush reviews the news and journal reports from this past week on RheumNow.com.  He discusses the GI side effects of IL-17 inhibitors, downstream revenues from rheumatology care and dietary prevention of gout. 

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Best of 2021: Jack of All Subspecialties

Jack Cush, MD

It's great to be a rheumatologist, but boy, it's getting harder and harder. You have to be a jack of all trades. You have to be good at cardiovascular disease, osteoporosis, vaccination, inflammatory bowel disease - it just never ends. This and more, as Dr. Cush summarizes more than a dozen journal articles, news reports and questions + cases.

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Best of 2021: EULAR Guidelines on Intraarticular Therapy

Jack Cush, MD

EULAR has published evidence-based recommendations on the use of intra-articular therapies (IAT) based on the literature review and recommendations of a multidisciplinary international task force. These IAT recommendations apply to adult patients with peripheral arthropathies.

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Telehealth Diet and Exercise Benefits Knee Osteoarthritis

Jack Cush, MD

Annals of Internal Medicine has reported the results of a randomized clinical trial showing that telehealth-delivered exercise and diet programs improved pain and function in knee osteoarthritis patients who were overweight.  While both were beneficial, exercise had a greater effect than die

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Osteoarthritis Initiative study looked at Hand OA. Among 3588 participants, 41% had hand OA by xray and 12.4 % by Sxs. Over 4 yrs, 27.3 % showed Xray OA progression. More in women (DIPs)>men (MCPs), but less in blacks https://t.co/WRZYcL7zFH

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Despite guidelines rec against hyaluronic acid knee injections, HA injx by ortho significantly increased from 1,090,503 in 2012 to 1,209,489 in 2018 (p = 0.04).amongsts Medicare beneficiaries https://t.co/fIEb5pq20I

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Dr. John Cush RheumNow ( View Tweet)

Retrospective study of 84 pts with Erosive Hand OsteoArthritis (EHOA)- 89% females DIPs erosions scores were higher than PIP’s. Comorbid dz = crystal arthritis (8%), RA (5%) & PsA (1%), Pain usually >5/10 w/ 1/3 responding to NSAIDs. Big Unmet need! https://t.co/jQ3yNgaZBA

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ICYMI: Physical Therapy is More Cost-Effective than Intraarticular Steroids in Knee OA https://t.co/My5xa8vEaP https://t.co/lGL57nwJiZ

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791 knee OA pts studied for progression after steroid (GC) (n=629) vs hyaluronic (HA) injxn (n=162). Knee OA progression was similar between groups for JSN (RR 1.00) & K/L grade (1.03); but IA GC had slightly lower TKR (HR 0.75 [CI 0.51–1.09]) https://t.co/74eg2Zvdy1 https://t.co/soXb7bdq6O

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ICYMI: Duloxetine added to usual analgesics failed to improve pain in 132 hip or knee OA pts by WOMAC pain scores: 1) Dulox + usual care vs 2) Usual care showed no diff in pain at 3 mos or 12 mos. https://t.co/2luWWDYP81 https://t.co/KAmqlnofVv

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Can PPI accelerate knee OA? UK cohort compared need for TKR in adults over 50yrs on PPI or H2 blockers. Those on omeprazole and pantoprazole had 21%-3& more TKR than H2B (but not elevated with lansoprazole, rabeprazole (HR=0.97) https://t.co/5TqFV3TpjG

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Global Burden of Disease Study shows that globally, from 1990 to 2019, the age-standardized incidence rate (ASIR) of hip osteoarthritis increased from 17.02 per 100,000 persons to 18.70 per 100,000 persons https://t.co/OJOnkAw1Dy

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Duloxetine added to usual analgesics failed to improve pain in 132 hip or knee OA pts by WOMAC pain scores: 1) Dulox + usual care vs 2) Usual care showed no diff in pain at 3 mos or 12 mos. https://t.co/9gR2PNVrPl

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RESTORE trial: yet another failure for PRP injections for knee #OA. Study of 288 Knee oA over 50 years - knee pain scores of −2.1 vs −1.8 on an 11-point scale (range, 0-10) and no difference between PRP and PBO at 12 moshttps://bit.ly/3pqldWU

Dr. John Cush RheumNow ( View Tweet)

Metanalysis of 11 studies, 46 819 participants shows low quality evidence that knee extensor muscle weakness is assoc w/ increased the odds of knee osteoarthritis in women (OR 1.85)and men (OR 1.43); also radiographic knee OA https://t.co/Md7eODvsIy

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NYC Hosp for Special Surgery is the 1st to use a "smart" knee arthroplasty - TKR with a smart sensor capable of monitoring steps, speed, range of motion & other knee functions fed back to the orthopedist = called Persona IQ, FDA authorized https://t.co/QR49JC7oCz

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What are the advantages and disadvantages of #ultrasound-guided intra-articular injections? Check out this slide👇from Lt.Col/Dr. Arjun's lecture: #iracon21 #IRACON2021 @2021Iracon @APLAR_org #mskus #rheumatology https://t.co/mhq9OgBk7a
sheila RHEUMarampa ( View Tweet)
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