All News
🧬 Do biomarkers predict #zasocitinib response in PsA?
YES: TYK2/IL-17 pathway markers predict ACR20 in 290pts Phase 2b RCT
#OP0184 #EULAR2026 @RheumNow https://t.co/AVlyrauI5q
Nelly ZIADE 🍀 Nellziade ( View Tweet)
🔎 Can US predict PsA progression from psoriasis?
YES: synovio-entheseal inflammation predicts progression in 183pts prospective cohort
#OP0183 #EULAR2026 @RheumNow https://t.co/7B9KU60qFd
Nelly ZIADE 🍀 Nellziade ( View Tweet)
Defining the TRM- SLE patient response.
Patient eligibility would be the key
#EULAR2026 @RheumNow https://t.co/5CzQYgc12K
Links:
Bella Mehta bella_mehta ( View Tweet)
DESIR Cohort 10-year data (OP0102): SIJ structural lesions in #axSpA progress slowly, but prior MRI bone marrow oedema predicts later structural damage. bDMARD exposure was associated with less erosion progression supporting early biologic treatment Abstr OP0102 @RheumNow
Antoni Chan MD (Prof) synovialjoints ( View Tweet)
#EULAR2026 OP022 We need to think beyond proteinuria to assess activity & response in #lupusnephritis. ReBioLup study showed 67% of patients with persistent histologic activity at 12 months (NIH=>4) still met criteria for complete clinical response @RheumNow https://t.co/bRFNrNLjJX
Md Yuzaiful Md Yusof Yuz6Yusof ( View Tweet)
#EULAR2026 OP0228 Is there “something in the air?” Data from US Market Scan: poor quality index was associated with increased risk of #SLE. Although causal inference cannot be deduced, seems an important environmental factor. To check air quality assoc with UV index @RheumNow https://t.co/1FOw7RDA9a
Md Yuzaiful Md Yusof Yuz6Yusof ( View Tweet)
Which ‘CAR’ to drive in #SLE?
Comparison of #CD19 #CAR-T
#allogenic vs #Autologous
➡️ comparing #molecular #responses from 2 #lupus studies N=12
Both improved cytokine signatures
For
#IFN & #neutrophils
Results similar not identical
?either
#POS0678 #EULAR2026 @RheumNow https://t.co/Lcpv3qJ6tU
Links:
Janet Pope Janetbirdope ( View Tweet)
#OP006 - Urine proteomics in LN tracks histo activity & treatment response better than proteinuria. Paired biopsies linked active disease to IFNI, IL12, complement & neut pathways- normalised in responders but persisted in non-responders. @RheumNow #EULAR2026 #EULARBest #Plenary
Mrinalini Dey DrMiniDey ( View Tweet)
🔬 Does synovial biopsy-guided treatment outperform standard care in PsA?
YES - 68% vs 45% DAPSA remission/LDA in 45pts
OP071 #EULAR2026 @RheumNow https://t.co/cLCR7I8QAm
Nelly ZIADE 🍀 Nellziade ( View Tweet)
#EULAR2026 OP002 In 20 active #lupus nephritis patients with paired kidney biopsy at baseline & 1 yr, urine proteomics showed histology response correlated with restoration of immune, coagulation and ECM-remodelling pathways. Need to advance this liquid biopsy in clinic @RheumNow https://t.co/KaZSYlA9V1
Md Yuzaiful Md Yusof Yuz6Yusof ( View Tweet)
ACPA and the Transition from Arthralgia to Rheumatoid Arthritis
Patients with clinically suspect arthralgia (CSA), a common prequel to rheumatoid arthritis (RA), showed different patterns of symptoms and progression depending on whether they tested positive for https://t.co/pCaYdEg1gZ
Dr. John Cush RheumNow ( View Tweet)
#EULAR2026 OP0125 It’s a case of “teamwork makes the dream work!” Instead of an index to capture heterogeneity in #Sjogren activity, the NECESSITY validated using data from 16 RCTs that a new composite tool, STAR has high sensitivity & specificity. Vital for use in RCTs @RheumNow https://t.co/ftx1uBP11A
Md Yuzaiful Md Yusof Yuz6Yusof ( View Tweet)
🔍 What defines a positive MRI for #axSpA?
SPARTAN-SSR consensus (n=1,050):
BME≥3 slices or 2/3 lesions in ≥3 SIJ quadrants
#OP0100 #EULAR2026 @RheumNow https://t.co/nfhzGxBZOm
Nelly ZIADE 🍀 Nellziade ( View Tweet)
HLA-Cw6: a marker of more severe and difficult to manage psoriatic arthritis?
POS0484
#EULAR2026
@RheumNow https://t.co/MIYZxuYT4v
Nelly ZIADE 🍀 Nellziade ( View Tweet)
Psoriatic arthritis #PsA sessions raised important topics on intercepting arthritis in psoriasis, treating obesity as a disease target, synovial biopsy to guide treatment, molecular imaging to reveal subclinical disease. More tomorrow. #Rheumatology @RheumNow #EULAR2026
Antoni Chan MD (Prof) synovialjoints ( View Tweet)
❎HIGH Type 1 #interferon
=
Worse #scleroderma
In both
#limited #lcSSc
&
#diffuse #dcSSc
Leeds cohort
?biomarker
#EULAR2026 @RheumNow ABST#POS1092
ABST#POS0395 https://t.co/cRrBIpLgP9
Links:
Janet Pope Janetbirdope ( View Tweet)
#OP088 at #EULAR2026 found that rare deleterious variants in telomere-related genes were associated with increased RA-ILD risk, independent of MUC5B status. The effect size was similar to that seen in idiopathic pulmonary fibrosis. @RheumNow
Mrinalini Dey DrMiniDey ( View Tweet)
Multiparametric renal MRI in LN:
Structural MRI can differentiate bet. active and stable dse
Exudative = active inflamm
In quanti analysis, low ADC values may reflect fibrosis.
A potential non-invasive biomarker?
OP092 @rheumNow #EULAR2026 https://t.co/IarTGOen7v
Links:
sheila RHEUMarampa ( View Tweet)
#OP087 explored cancer polygenic risk scores (PRS) in RA. RA was assoc with lower risks of breast and colorectal cancer across all PRS categories, while high prostate cancer PRS may identify RA patients with increased early prostate cancer diagnoses. @RheumNow #EULAR2026 https://t.co/WMqqSFADlW
Mrinalini Dey DrMiniDey ( View Tweet)
68Ga-RGD PET/CT in PsA reveals large chunk of “silent” synovitis
15 pts 1020 joints
35% affected joints clinically silent
PET signal correlation w/ disease burden:
DAPSA (ρ=0.66)
CRP (ρ=0.69)
Pilot study — not confirmed with US
Needs validation but intriguing signal
#OP068 https://t.co/nhS7PDZN0A
Links:
Aurelie Najm AurelieRheumo ( View Tweet)
