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NY Times on Arthritis Prevention
A reader question ("Ask Well") to the New York times wonders "is arthritis avoidable"?
A recent survey suggests that up to 60% of adults have been told by an HCP they had some form of arthritis.
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Want to Go Far, Go Together (4.21.2023)
This week on the podcast Dr. Jack Cush reviews the news, regulatory announcements and novel journal reports including a profile on pseudogout, the safety of immune checkpoint inhibitors in RA patients and the diagnostic importance of neutrophils.
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Aging Mechanisms Tied to Giant Cell Arteritis
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MedPage Today
Senescence pathways are involved in giant cell arteritis (GCA), an analysis of patient tissue samples suggested, which may account for the efficacy of one agent now used for the disease and another in commercial development.
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Sex-Specific Differences in Psoriatic Arthritis
A systematic review of published literature on PsA, clinical features, disease activity, and PROs shows generally higher levels of disease activity in women, compared to men with PsA.
https://t.co/EaKmos9ViQ https://t.co/djfteIy8WX
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Dr. John Cush RheumNow ( View Tweet)
NIH sponsored nationwide survey assessed 1,462 SLE pts (9% men; 81% women). Male SLE pts had more MI & difficultly w/ medical forms than F. Female SLE had more fatiguer and higher educational levels. Both had barriers to health care access (40-47%) https://t.co/1u7bsyn3fD https://t.co/RTXyiuP972
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Dr. John Cush RheumNow ( View Tweet)
JAMA Dermatology Patient Education page - Sarcoidosis of the Skin https://t.co/yDbwRUR8DK https://t.co/F8lsoh6s1l
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Dr. John Cush RheumNow ( View Tweet)
Immune Checkpoint Inhibitor Safety with Pre-existing Rheumatoid Arthritis
Lancet Rheumatology has published a retrospective analysis showing patients receiving ICI for cancer have the same outcomes even when they have pre-existing RA.
https://t.co/aFNZX5YaLD https://t.co/ZY9Ie8TOPc
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Dr. John Cush RheumNow ( View Tweet)
Brigham review (2018-2022) of 47 CPPD pts: M=F, mean age 72 yrs
68% w/ acute CPP arthritis
40% w/ CPP inflammatory arthritis
62% w/ OA with CPPD.
Compared to Gout, CPPD Significant unmet Rx need & lower RAPID3 (8.1 vs 12.1) https://t.co/cLNjGxi6qF https://t.co/76PoepxRjR
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Dr. John Cush RheumNow ( View Tweet)
The European Commission has approved upadacitinib (Rinvoq) for the Treatment of Moderately to Severely Active Crohn's Disease https://t.co/Ltun2fdRn9 https://t.co/033PCqIlrv
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Dr. John Cush RheumNow ( View Tweet)
Retrospective study of 147 THA and TKA pts w/ acute/chronic complaint - 39 pts Dx w/ prosthetic joint infection (PJI). Absolute numbers of neutrophils (PMNs) best predicted PJI (THA > 3,600 PMN/µl; TKA >2,000 PMN/µl (sensitivity 97%; specificity 93.5%) https://t.co/hZ8rpgJUZu https://t.co/CiSEvg9xPQ
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Dr. Alexis Ogdie discusses sex differences in patients with psoriatic arthritis. Learn more.
https://t.co/JTSHAKBfhN https://t.co/f0rfDQAY6T
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Dr. John Cush RheumNow ( View Tweet)
Join us 4/25 as we conclude our Women in Rheumatology campaign by focusing on what's next. Our panelists will recap the challenges addressed this month and discuss a strategy to suppot women in rheumatology.
https://t.co/DP4S2hf5Tz
@uptoTate @KDAO2011 @gwenesta_melton https://t.co/rcglaZxqoF
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Dr. John Cush RheumNow ( View Tweet)
New download available!
Private Practice vs Academic Medicine
https://t.co/APzQGpcwm6 https://t.co/qAtyPFGquV
Links:
Dr. John Cush RheumNow ( View Tweet)
Sex-Specific Differences in Psoriatic Arthritis
A systematic review of published literature on PsA, clinical features, disease activity, and PROs shows generally higher levels of disease activity in women, compared to men with PsA.
https://t.co/dMvLSwzWIt https://t.co/Cz8aIID3HX
Links:
Dr. John Cush RheumNow ( View Tweet)
TNR: Private Practice & Academia
In this session, our panelists addressed the big questions of: "How do I choose between private practice and academia?" and "How do I advance in my career?".
https://t.co/yMJ5mCtSXX
@KDAO2011 https://t.co/eeFYkLYsAh
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Dr. John Cush RheumNow ( View Tweet)
Dr. Philip Mease speaks about the effect of sex and gender on rheumatology disease activity and treatment response. Learn more.
https://t.co/vKZfFLFmgs https://t.co/kRA0w9hRX7
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Dr. John Cush RheumNow ( View Tweet)
CIRCS study: Comparison of 3188 Gout (733 M: 355 F) and ~10K non-gout. Found that the risk of gout in men linked to HTN (HR 1.41)and alcohol (HR 1.23 & 1.41), but that only smoking was a risk factor among women (HR 1.66). https://t.co/ODQW3SUjet https://t.co/Y8FTpbeXd5
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Dr. John Cush RheumNow ( View Tweet)
NIH sponsored nationwide survey assessed 1,462 SLE pts (9% men; 81% women). Male SLE pts had more MI & difficultly w/ medical forms than F. Female SLE had more fatiguer and higher educational levels. Both had barriers to health care access (40-47%) https://t.co/A0Zv5IvXnh https://t.co/BFMspCs6yE
Links:
Dr. John Cush RheumNow ( View Tweet)
CDC defines Health equity as a state where everyone has a fair & just opportunity to attain their highest level of health; requires efforts to: address injustices; overcome economic;social obstacles to health & eliminate preventable health disparities https://t.co/fYviqSBIse https://t.co/XuRZ4xJdXH
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Dr. John Cush RheumNow ( View Tweet)
Renal Function Safe With Pegloticase-MTX Combo for Gout
For patients with uncontrolled gout, estimated glomerular filtration rate (eGFR) remained stable with combination pegloticase (Krystexxa) and methotrexate treatment, researchers reported.
https://t.co/cInxAUrQiR https://t.co/MoBKUMKfjP
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Dr. John Cush RheumNow ( View Tweet)