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Women Rheumatologists Leading in the Private Sector

d Priya Reddy, MD, FACR

Women physician leaders have made significant contributions in various fields, such as business leaders as CEOs and board members, public health through national and international advocacy efforts, and the non-profit sector.

"To Lead or Not To Lead" - that is the question.

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Immune Checkpoint Inhibitor Safety with Pre-existing Rheumatoid Arthritis

d Jack Cush, MD

Lancet Rheumatology has published a retrospective analysis showing patients receiving immune checkpoint inhibitors (ICI) for cancer have the same outcomes (mortality and severe immune-related adverse events (irAEs)) even when they have pre-existing rheumatoid arthritis (RA).

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equity

Gender equity in academic rheumatology

d Nicola Dalbeth, MBChB, MD, FRACP, FRSNZ

Although almost half of our specialist rheumatology physician workforce is now women, gender inequity in career progression within academic rheumatology is a persistent problem. A recent analysis of the US rheumatology workforce showed that although women were well represented in rheumatology program director and division director leadership roles, women academics were less likely to be full or associate professors, had fewer publications, and received fewer NIH grants.

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Study of 9558 pts found significant associations betw migraine and CTS Median nerve decompression (OR, 1.3) & multiple nerve decompressions (OR, 1.7). Also assoc w/ migraine: psych dz, RA, CVS, hypothyroid, HTN, COPD https://t.co/cIdkACHGwB https://t.co/VO3VqujzSQ

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Dr. John Cush RheumNow ( View Tweet)
Real world interchangeabilty study compared rituximab to biosimilar ( CT-P10) in 128 Rheum pts (CT-P10= 64; RTX= 64), with 41% of pts switched from RTX to CT-P10. Both Rx had Comparable Gr 2 infuxion Rxs, infection #s & hypogammaglobulinemia (p > 0.05) https://t.co/RNxt7Xn7MJ https://t.co/u3yJNQQIMC

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Dr. John Cush RheumNow ( View Tweet)
Doctor’s Contracts: Pitfalls and Traps Dr. Dao ( @KDAO2011) spoke with Andrea Liberatore, JD, to explain what to look for in a contract. https://t.co/w44pWWyhpo https://t.co/fy5vlve4IQ

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Dr. John Cush RheumNow ( View Tweet)
Retrospective study on prescribing by male vs female RHEUMs, found that women (in private practice, >10 yrs) were less likely to be High steroid prescribers. RA Pts more likely to Rx steroids = male sex, >prior biologics, opioid use, w/ comorbidities & freq infx https://t.co/eO3yJRCfOR
Dr. John Cush RheumNow ( View Tweet)
The European Commission has approved upadacitinib (Rinvoq) for the Treatment of Moderately to Severely Active Crohn's Disease https://t.co/Clzca7jU5b https://t.co/nNFGe5fF25

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Dr. John Cush RheumNow ( View Tweet)
12 mos. serial study of 71 pts with gout found 42% with at least 1 gout flare (median=2) over 12 mos. US eval. showed "Flare" pts had signif more MSU deposits (6.7 vs 2.9) & power Doppler (3.73 vs 0.82)vs controls. By US- were 17-29% more likely to flare. https://t.co/icDyNEsCa6 https://t.co/86pgBzG9MC

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Dr. John Cush RheumNow ( View Tweet)
Lillys IL-23 inhibitor (Mirakizumab) has suffered a minor setback receiving a "complete response letter" from the FDA regarding MIRA application (BLA) for use in ulcerative colitis. The CRL hold up is related to the manufacturing issues (not data/safety) https://t.co/Xs93pFNFAp https://t.co/vlVP8qiqGr

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Dr. John Cush RheumNow ( View Tweet)
Pain and Opioid Updates The CDC and FDA provided new updates on the scope of pain in the USA and guidance on the use of opioids. https://t.co/jjN9zvX7rV https://t.co/kY3kX1S8vq

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Dr. John Cush RheumNow ( View Tweet)
Retrospective study of 147 THA and TKA pts w/ acute/chronic complaint - 39 pts Dx w/ prosthetic joint infection (PJI). Absolute numbers of neutrophils (PMNs) best predicted PJI (THA > 3,600 PMN/µl; TKA >2,000 PMN/µl (sensitivity 97%; specificity 93.5%) https://t.co/pxKcsTT6tn https://t.co/IQZ0DSUxwc

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Dr. John Cush RheumNow ( View Tweet)
Best Treatments for Immune Checkpoint Inhibitor-associated Arthritis A retrospective study of cancer patients who developed ICI-IA shows that biologic DMARDs were more effective than csDMARDs in rapid control of arthritis. https://t.co/EQjSgav0by https://t.co/CZ0IqR3UXM

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Dr. John Cush RheumNow ( View Tweet)
Clinical Profile of RA-associated Interstitial Lung Disease A prospective, cross-sectional analysis of patients with rheumatoid arthritis (RA) shows those with interstitial lung disease (ILD) tend to be older, obese and have a smoking history. https://t.co/FazEGcHh5H https://t.co/oh6oIpj21k

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Dr. John Cush RheumNow ( View Tweet)
4/18 Tuesday Night Rheumatology: Private Practice & Academia Our panelists will address the big questions of: "How do I choose between private practice and academia?" and "How do I advance in my career?" Sign up for this session and all sessions here: https://t.co/TrMpNmHpj3 https://t.co/3vIwxK0CUU

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Dr. John Cush RheumNow ( View Tweet)
"If you want to go fast, go alone. If you want to go far, go together." -(African proverb)

Dr. John Cush RheumNow ( View Tweet)

COVID had a significant effect on mental health of inflammatory rheumatic Dz (IRDs) pts. UK NHS survey of 639 IRD (70% RA, 16% PsA) saw 40% w/ mod/severe pandemic impact on physical & mental health; 29% w/ depression, 22% anxiety; affecting Women>males https://t.co/kcAwa2Lks2 https://t.co/R6tk2aOrGQ

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Dr. John Cush RheumNow ( View Tweet)
Japanese cohort study shows Lung cancer is more common in males w/ elder-onset dermatomyositis - risk increased by Smoking, anti-TIF1-γ-Abs and elevated MLR (monocyte to lymphocyte ratio) https://t.co/C7BTAV5gCj https://t.co/YGq6sUbLOh

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Dr. John Cush RheumNow ( View Tweet)
Retrospective study of 42 pts w/ cocaine-induced midline or systemic vasculitis; Current cocaine use common (20/23 + urine tox, including pts who prev. deniedcocaine). Found: septal perfs (75%), oronasal fistula(15%), less(27%) systemic Sxs, 56% PR3-ANCA+https://t.co/tCt8l6Neb3 https://t.co/LzEpP5Z2fT

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Dr. John Cush RheumNow ( View Tweet)
Antiphospholipid Antibodies With Incident Cardiovascular Events Are antiphospholipid antibodies (aPL) associated with atherosclerotic cardiovascular (ASCVD) event risk? https://t.co/5KhXWgF4RA https://t.co/BjIINjM1ml

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Dr. John Cush RheumNow ( View Tweet)

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