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70% of #AOSD pts were females! Large HCA database study - incidence rate - 0.16 - 0.21 per 100,000 (similar to French studies).
24% required ICU level of care, 12% had PNA (fig)
Mortality is higher than other cohorts - 3.2%
#ACR22 @RheumNow abst#0829 https://t.co/fcFUnExYOE
Bella Mehta bella_mehta ( View Tweet)

🤓Active learning creates a greater + impact in patient care using cognitive errors metacognition - study by Dr Milne et al.
☑️Reflection, #metacognition enhances clinical competence, incorporate in curriculum
#ACR22 @RheumNow #meded @rheumarhyme @PhRheumaJr @GerRheumDoc https://t.co/veefYToXBV
sheila RHEUMarampa ( View Tweet)

#ACR22 The Great Debate: to treat subclinical #Rheumatoidarthritis or not. @Janetbirdope counted hands manually in person. Let's check out the #socialmedia community. What is your definition of sub-clinical RA? @RheumNow
Md Yuzaiful Md Yusof Yuz6Yusof ( View Tweet)

Romo works even better in higher risk patients. More ammunition to use up-front. Availability is a limiting factor though.
@RheumNow #ACR22 #osteoporosis https://t.co/90X97jVJcP
Julian Segan JulianSegan ( View Tweet)

Dr. Jack Cush discusses uptake of #telemedicine in 2020 and the relative decline of uptake since then:
@RheumNow -- What's your take on continuing to use #telehealth for rheum visits? #ACR22 https://t.co/OB5Wnnq6Fh
CreakyJoints.org CreakyJoints ( View Tweet)

“Go digital or go home” -- Dr Jack Cush says on #telemedicine in a session at #ACR22 @RheumNow https://t.co/4PzGgS900t
CreakyJoints.org CreakyJoints ( View Tweet)

Dr. Megan Clowse gives 2 major tips on how rheumatologists can help avoid catastrophic pregnancies:
✳️Routinely ask open-ended Qs to promote HONEST dialogue about repro health
✳️Provide ACCURATE info & guidance using discussion guides and handouts
#ACR22 @RheumNow @rheumarhyme https://t.co/qXwKMdJmR8
sheila RHEUMarampa ( View Tweet)

Infections in pre-RA: a cause or a consequence?
Rheumatoid arthritis is known to be associated with a higher risk of infections, and this occurs for multiple reasons: immune dysfunction, systemic inflammation, comorbidities, and treatments.
https://t.co/N91Goop92l https://t.co/yvnRrsHSCB
Links:
Dr. John Cush RheumNow ( View Tweet)

Dr. Michael Holers on preclinical RA
"Individuals who are anti-CCP positive are not clinically well. We just can't see what is going on"
@RheumNow #ACR22
Robert B Chao, MD doctorRBC ( View Tweet)

Emphasis that drug holiday is NOT drug retirement in osteoporosis. Ideal time to re-initiate is quite uncertain however. Continue to monitor DEXA and fracture risk factors.
@RheumNow #ACR22 #osteoporosis https://t.co/iLKrxdzpAR
Julian Segan JulianSegan ( View Tweet)

Valero et al. Combined biologics in PsA. @RheumNow #ACR22 Abstr1044 https://t.co/7nNf0Ktf0M https://t.co/CIE9BnBFvx
Richard Conway RichardPAConway ( View Tweet)

The Great Debate! Should you treat pre-clinical RA?
First - likelihood of RA?
If you have +ACPA or RF in sputum, there is 67% chance of developing clinical RA!
@RheumNow #ACR22 https://t.co/K7pUhvbEDR
Robert B Chao, MD doctorRBC ( View Tweet)

💠CYC confers a 27% risk of congenital malformations and ⬆️miscarriage rate
💠Contraception is recommended during use and 3 mos after tx
#ACR22 @Rheumnow https://t.co/A73vCMZdxd
sheila RHEUMarampa ( View Tweet)

Can we predict PsA incidence and prevalence trends?
Germany long-term projection 2040
3 scenarios:
1. increase 5%/yr
2. stable
3. decrease 5%/yr.
Best scenario (3) = peak diagnoses in 2028. Are medical resources ready for it?
https://t.co/ws87zDukuM
Abs#1019 #ACR22 @Rheumnow https://t.co/dqkfrag0w2
Aurelie Najm AurelieRheumo ( View Tweet)

Atypical femoral fracture risk increases over time. Risk decreases slowly as well with time off treatment. Absolute risk remains relatively low however.
@RheumNow #ACR22 #osteoporosis https://t.co/pcIfhRW4WJ
Julian Segan JulianSegan ( View Tweet)

💉COVID-19 vaccination in pregnant pts with rheumatic disease💉
🤰⬇️pre term births in vaccinated
🤰PPROM ⬆️ unvaccinated
✅More support 4 importance of covid vacc in our 🤰
Stellar work from covid GRA- Fantastic presentation by @Sineadm15 #ACR22 @RheumNow @RichardPAConway https://t.co/LLaLJSqS6W
Patricia Harkins DrTrishHarkins ( View Tweet)

Good BMD gains in switching BP->denosumab, especially in first few years. #sequentialtherapy
@RheumNow #ACR22 #osteoporosis https://t.co/t1hItKn8sB
Julian Segan JulianSegan ( View Tweet)

Most rheums round down on dosing because of the weight based recc's, but hydroxychloroquine dosing less than 5 Mg/kg/day leads to increased hospitalizations for #SLE flares abst#1654 #ACR22 #PressConference @rheumnow https://t.co/GGnnl14cy9
TheDaoIndex KDAO2011 ( View Tweet)

Phase 1 data shows Ebdarokimab (IL12/23i) safe and well tolerated in moderate to severe plaque psoriasis patients. Abs 0752 #ACR22 @RheumNow https://t.co/QqTE4WJtDa https://t.co/eMaEurZAr0
Dr. Rachel Tate uptoTate ( View Tweet)

The great debate
Next steps to develop RA prevention
Kevin Deane
“It’s time to move from disease modifying drugs to disease modifying therapeutic approaches”
#ACRdebate #ACR22 @RheumNow https://t.co/3vt58sXlDx
Aurelie Najm AurelieRheumo ( View Tweet)