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#ACR22 Year in Review. Dr Langford summarised significant progress attained in 2022 in combating #COVID and protect our immunosuppressed patients @RheumNow https://t.co/lZSDRj3bkm
Md Yuzaiful Md Yusof Yuz6Yusof ( View Tweet)
Key points in managing MDA5+ DM
1. Monitor lungs - HRCT/PFTs
2. Test muscle endurance (ref: IMACS site) not just strength
3. Close observation
4. MTX/MMF initial treatments
5. Repeat muscle biopsy if diagnosis unclear
Meet the Expert Lundberg I, IMM session @RheumNow #ACR22 https://t.co/ZVFsYgDBx2
Dr. Antoni Chan synovialjoints ( View Tweet)
Key points in managing MDA5+ DM
1. Consider Tofacitinib 5-10mg bd
2. Low to mid dose Prednisolone 20-30mg tapering
3. Other Rx: Tacrolimus, IVIG
4. Poor prognostic factors: lymphopenia, raised ferritin, old age, rapid ILD progression
Wang GC, IIM session @RheumNow #ACR22 https://t.co/UF2PjAg0Mw
Dr. Antoni Chan synovialjoints ( View Tweet)
Therapies for AS and nr-AxSpA are coming together. Both AS and nr-AxSpA present with similar burden of disease. TNFi, IL-17i and JAKi now approved for use in nr-AxSpA.
Jose U Scher, SpA Review @RheumNow #ACR22 https://t.co/vcHcd7OyAU
Dr. Antoni Chan synovialjoints ( View Tweet)
Mimics of Sjogren’s Syndrome @RheumNow #ACR22 https://t.co/nEAXKb6qF0
Dr. Antoni Chan synovialjoints ( View Tweet)
“The Stone Age did not end because of a shortage of stones. We need new solutions to our problems” Abraham Verghese. Amazing insight into our challenges in clinic today at the #ACR22 opening session @RheumNow
Dr. Antoni Chan synovialjoints ( View Tweet)
GCA Fast Track clinics are nice - but usually need specialized ultrasound.
What if you don't have it? (also, COVID?)
@PennRheum implemented *without* ultrasound
Excellent outcomes
The early referral triage makes all the difference. Knowledge is power ABST0463 #ACR22 @RheumNow https://t.co/rjkVERW559
David Liew drdavidliew ( View Tweet)
More details at https://t.co/4U8v7oeUYW
Enormously powerful in these times of rheumatology workforce shortage. I would love to see this in Australia and elsewhere - so much to learn. Congratulations to all involved, and thanks @ACRheum and @UCSF for supporting #ACR22
David Liew drdavidliew ( View Tweet)
Just published! QR code attached! #ACR22 @RheumNow https://t.co/lMD0mFoT4M
Patricia Harkins DrTrishHarkins ( View Tweet)
“Rheumatic diseases - diseases of accelerated aging”
With age:
⚖️ fat ⬆️
💪🏻 muscle ⬇️
👉 results in ⬇️fn ⬇️gait speed ⬇️grip
🌟what can we do?
⚡️start with basic diet and exercise advice
✅caloric restriction (⬇️350cal/day)
✅ resistance training
#GeriRheum #ACR22 https://t.co/6KRrwCWBEZ
Patricia Harkins DrTrishHarkins ( View Tweet)
Botson et al. 52 week results MIRROR trial. MTX added to pegloticase. 71% vs 39% SU <6mg/dl. Infusion reaction 13% vs 32% if ab+ 0% vs 30% ab- @RheumNow #ACR22 Abstr#0001 #ACRbest https://t.co/1c3Va9NxNX https://t.co/dPGDyWue4G
Richard Conway RichardPAConway ( View Tweet)
England et al. Influence of FVC on choice of b/tsDMARD in RA-ILD. FVC predicts hospitalisation and mortality. However, it did not appear to influence choice of b/tsDMARD. Overall 67% of RA-ILD patients initiated TNFi, weird! @rheumnow #ACR22 Abstr#245 https://t.co/swuNHv96WD https://t.co/vy5FUPnNjo
Richard Conway RichardPAConway ( View Tweet)
Interesting observation: Late-onset PsA assoc'd w/ male sex, greater structural damage, higher frequency of arthritis, and greater loss of functionality (BASFI). Interestingly, shorter time of symptom duration to dx. Abs 0377 #ACR22 @RheumNow https://t.co/m15c37FltD https://t.co/3LRy4Ltde6
Dr. Rachel Tate uptoTate ( View Tweet)
#ClinicalPearl #Methotrexate is recommended for Rx in all EXCEPT…#ACR22 @RheumNow
Janet Pope Janetbirdope ( View Tweet)
Difficult to treat #rheumatoidarthritis - phenotypes need to be defined and order of Rx may be v Impt. Well, it is really difficult @RheumNow #ACR22 session 12S127 https://t.co/x3bkUP590A
Janet Pope Janetbirdope ( View Tweet)
So does PsA affect your capacity to work?
DISCOVER-2 analysis:
It’s presenteeism, not absenteeism which is the issue
PsA pts drag themselves into work, but treating them helps them actually do their job. We need to fund more rheumatologists!
ABST0509 @RADoctor #ACR22 @RheumNow https://t.co/Jnac6mV9O5
David Liew drdavidliew ( View Tweet)
#RheumPearl: Dr. J Stone shares useful #ophthalmology terms that #rheums should know. Note that IOI may not be idiopathic (do the workup- it might be #sarcoid myositis). Does @DGlaucomflecken have anything to add? #ACR22 @rheumnow https://t.co/bxWm7MlePj
TheDaoIndex KDAO2011 ( View Tweet)
Michailidou et al. Predictive models VTE in GCA. Predictors Age, inpatient status at the time of diagnosis of GCA, numberof admissions before diagnosis of GCA, Charlson comorbidity index @rheumnow #ACR22 Abstr#0458 https://t.co/TVZ53sERrS https://t.co/JzUuEZThY0
Richard Conway RichardPAConway ( View Tweet)
BIOBADASAR study of cancer risk in RA patients with prev cancer treated with b/tsDMARD. No increased risk, but yet again abatacept numbers are making me slightly nervous! @rheumnow #ACR22 Abstr#0267 https://t.co/H8gYm9STT3 https://t.co/sEIS6Ljwao
Richard Conway RichardPAConway ( View Tweet)
Rheumatology Secrets & Pearl Lecture
with Dr. John Stone:
- Patient presenting with fever, headache, neck pain, and CPPD of multiple joints.
- Consider Crowned Dens Syndrome. CT Neck showing calcification around Odontoid Process
@RheumNow #ACR22 https://t.co/Md1bqzPyr5
Akhil Sood MD AkhilSoodMD ( View Tweet)