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Rooney et al. Seasonality of GCA in UK and Ireland - DCVAS/TABUL/local hospital combined dataset. 2 peaks - spring/early summer every year, and a second peak most years in autumn or winter. @rheumnow #ACR22 Abstr#0495 https://t.co/Trz8ou9xGh https://t.co/jcS3Z30nz8
Richard Conway RichardPAConway ( View Tweet)
Do you see #JAKis causing weight gain? 429 Pts BUT during #COVID19 - 68% gained wt in RA 1.5 Kg mean; and more in SpA 71% w 2.6 Kg. Was it Rx or COVID related? #ACR22 abst0291 @RheumNow
Janet Pope Janetbirdope ( View Tweet)
Ruiz et al. bDMARD/tsDMARD use in RA after breast cancer. Low use, 15.5% on bDMARD, 1.5% on tsDMARD. Stable use over last 10 years @rheumnow #ACR22 Abstr#0080 https://t.co/0L6uuVtQQw https://t.co/xBH1bUdeSD
Richard Conway RichardPAConway ( View Tweet)
#disparities study using admin data
- 580 pts with incidence childhood #SLE with LN
- LN codes before SLE codes - more likely publicly insured, rural area, Hispanic ethnicity, kidney transplant
- differential access!!
@RADoctor @rheumnow #ACR22 abst#0068 https://t.co/uryCZq94dX
Bella Mehta bella_mehta ( View Tweet)
Early Izokibep (IL17Ai) data demonstrated clinically meaningful, dose-dependent improvement across PROs, particularly sleep, pain, function ,+ SF36 and PsAID subdomains in PsA pts. Pts w/ baseline enthesitis had greater benefit. Abs 0199 #ACR22 @RheumNow https://t.co/sXVdwGPVnd https://t.co/Cxyfp6OXOY
Dr. Rachel Tate uptoTate ( View Tweet)
Did you get the updated #COVIDbooster before you arrived at #ACR22? Answers are anonymous @rheumnow
TheDaoIndex KDAO2011 ( View Tweet)
Use of AI to detect sacroilitis in axSpA and nr-axSpA.
Pre-trained AI neural network can detect sacroilitis, especially new data, similar to human radiology experts.
Abs#0383 @RheumNow #ACR22 https://t.co/5hdrKxT3HP
Robert B Chao, MD doctorRBC ( View Tweet)
‼️Frailty in Vasculitis‼️
👉VascStrong using VPPRN
✏️ FRAIL scale
👉 n=328
🌟21.6% frail
🌟42.1% pre frail
💥 frailty assoc ⬆️ pain, fatigue and ⬇️ mood and fn
💥⬆️ wt and females higher frailty
Abst0444
#ACR22 #GeriRheum @RheumNow @SattuiSEMD
Patricia Harkins DrTrishHarkins ( View Tweet)
Elderly onset #rheumatoid #arthritis does worse than younger people. Data from Japan - Benefit is less and side effects more. Less remission and worse HAQ scores. ?due to RA differences or changes due to age or both or neither? #ACR22 abst0244 @RheumNow @ACRheum https://t.co/FqvLA765Cu
Janet Pope Janetbirdope ( View Tweet)
Remuzgo-Martinez et al. Serum endothelin-1 in CTD-ILD. Significantly higher levels than healthy controls. No difference between CTD-ILD and IPF. @rheumnow #ACR22 Abstr#0123 https://t.co/Jf3AumSnjt https://t.co/Xki8LEEcnV
Richard Conway RichardPAConway ( View Tweet)
de Boysson et al. Beta-blockers may prevent aortic dilation in LVV GCA (0% vs 23%). 65 patients, retrospective , and patients were on beta-blockers for other reasons, but thought-provoking @rheumnow #ACR22 Abstr#0477 https://t.co/AVmIwCk3LV https://t.co/Plv5tcN5mR
Richard Conway RichardPAConway ( View Tweet)
Auroux et al report differential micro-RNA signatures in hand OA compared to controls (15 upregulated, 4 downregulated). No difference erosive vs non-erosive hand OA. May elucidate pathophys but also ?treatment target @rheumnow #ACR22 Abstr#0023 https://t.co/Kzv8WDmHRU https://t.co/4nCuTjvR6d
Richard Conway RichardPAConway ( View Tweet)
Gisslander et al Cluster analysis in AAV in Sweden. 5 groups. 2 PR3+ groups, younger, ENT or nerve involvement - good prognosis. 2 older MPO+ groups - lung or renal involvement - worse prognosis. @rheumnow #ACR22 Abstr#0433 https://t.co/itokBTOujS https://t.co/PG6CpZvN1a
Richard Conway RichardPAConway ( View Tweet)
#abst0129 #acr22 @rheumnow analysis 6 Euro studies of active RA, PsA, axSpA &secondary failure of TNFαi showed golimumab to be effective 2nd-line Rx. GLM show improvement in Dis activity, QoL& high retention( 2/3 pts on Rx after 12mo). https://t.co/6OeKwJpqQp
Olga Petryna DrPetryna ( View Tweet)
Kirby et al @colmkirby22 . Subclinical GCA in newly diagnosed PMR. 25 patients. 20% had LVV on US - TA in all, axillary in 1. All 5 developed clinical GCA over 1 year. @rheumnow #ACR22 Abstr#0478 https://t.co/xMMjH2XCUD https://t.co/JEtwEGTEbP
Richard Conway RichardPAConway ( View Tweet)
Papo et al. EGPA. Predictors of relapse: Age at diagnosis GC dependent asthma before EGPA (HR1.57), Arthralgia(HR 1.27),myocarditis(HR1.74),peripheral neuropathy(HR 1.39) MPO-ANCA(HR1.56), baseline eosinophil count @rheumnow #ACR22 Abstr#0432 https://t.co/Yq6Eomr9z0 https://t.co/8CYOYROi72
Richard Conway RichardPAConway ( View Tweet)
Genicular nerve block for knee OA - exciting short-term symptomatic option, great Australian work on the Ignite stage. Looking forward to seeing more!
ABST1892 Shanahan et al @Flinders #ACR22 @RheumNow https://t.co/ssYoXj4wjg
David Liew drdavidliew ( View Tweet)
Ab0373 #ACR22 SpA-U
@ChristianaSiero:
42 pts w/ SpA-r uveitis, 190 attacks
Uveitis more severe: smoking, axial & peripheral involvement, BASDAI>4, HLA-B27+, female, CRP elevation, h/o bilateral ocular involvement
Less severe: shorter disease evolution, nml vit D
@Rheumnow
Eric Dein ericdeinmd ( View Tweet)
Important! Abst#2054 A Novel Treatment Response Measure (TRM) for SLE Clinical Trials is being developed, an international collaboration by clinical-academics, regulatory experts, pt reps, & industry. It will impact how clinical trials will be designed. #ACRbest @rheumnow #ACR22
TheDaoIndex KDAO2011 ( View Tweet)
Be careful what you look for? Serum from 32 ACPA+ Pts and 30 ACPA neg all w #rheumatoidarthritis had multiplexed Ab- screening microarray w 1600+ antibodies. Novel Abs were identified in each group vs healthy controls. What does this mean? #ACR22 abst#0256 @RheumNow @ACRheum https://t.co/mqL8kuUkxY
Janet Pope Janetbirdope ( View Tweet)