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There have been many cases of Kawasaki vasculitis in kids ith COVID-19; now Lg vessel vasculitis in 79 yo Japanese man w/ COVID-19 pneumonia, CRP 17.7 mg/dL, spiking fevers and CTA and FDG-PET evid of aortic and LVV, neg ANCA, nl IgG4, but was HLA-DR4+. https://t.co/UpL4Z1qK2p

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https://bit.ly/312iJkV

Dr. John Cush RheumNow ( View Tweet)

Oct 14, 2020

COVID Transmission from Young to Old

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d Jack Cush, MD

Oct 13, 2020

The CDC has analyzed temporal trends in percent positivity by age group in COVID-19 hotspot counties before and after their identification as hotspots.

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Observational study of 123 Spanish rheumatic dz pts w/ COVID-19, finds 54 hospitalized. Admitted pts were 69.7 yrs, and 22% died. Admission was assoc w/ older age, autoimmune dz (vs inflammatory arthritis; OR: 3.55), but not DMARD Rx. https://t.co/UWNyhOKbvF

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https://bit.ly/3dmbfhs

Dr. John Cush RheumNow ( View Tweet)

Oct 13, 2020

The RheumNow Podcast is up - Bad Disease & Bad Outcomes. COVID consequences, TNFi Switching in SpA, psychosis in lupus? Watch it here> https://t.co/ced3cKg5eB or listent to podcast on iTunes> https://t.co/FHJv01AAbC or SoundCloud> https://t.co/e4nWr3wECz

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https://bit.ly/2IgJpaZ

Dr. John Cush RheumNow ( View Tweet)

Oct 11, 2020

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Dr. John Cush RheumNow ( View Tweet)

Oct 11, 2020

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https://bit.ly/33HV5vB

Dr. John Cush RheumNow ( View Tweet)

Oct 11, 2020

Hydroxychloroquine Shows No Benefit in Hospitalized COVID-19 Patients

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d Jack Cush, MD

Oct 09, 2020

The NEJM reports on a controlled clinical trial showing patients hospitalized with Covid-19 given hydroxychloroquine (HCQ) do not have a lower incidence of death compared to those receiving routine care.

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Another case of COVID-19 Arthritis; 58 yoF w/ non-severe COVID-19, (by qRT-PCR ) had arthralgia, fever, cough, nausea, diarrhoea, dysgeusia, and devloped ankle arthritis CRP 7·36 mg/L, lymphopenia (1·29) persistent arthritis (by US) and +Sars-CoV-2 in SF. https://t.co/4Pg1Vq30EN

Links:

https://bit.ly/3dcB7MO

Dr. John Cush RheumNow ( View Tweet)

Oct 09, 2020

RheumNow Podcast – Bad Disease & Bad Outcomes (10.9.20)

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d Jack Cush, MD

Oct 08, 2020

Dr. Jack Cush Reviews the news and journal articles from the past week on RheumNow.com.

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Comparison of 34,128 COVID and 84,585 influenza pts; COVID-19 patients have been more typically been male, younger, and have fewer comorbidities and lower medication use than flu. (data from USA, South Korea, Spain) https://t.co/VUzVxFdBra

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https://go.nature.com/2GHcMT8

Dr. John Cush RheumNow ( View Tweet)

Oct 08, 2020

Systemic Steroids Reduce Mortality in COVID-19

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d Jack Cush, MD

Oct 06, 2020

JAMA Internal Medicine reports an analysis of COVID-19 clinical trials showing that critically ill patients with COVID-19 treated with systemic corticosteroids have an overall lower mortality rate.

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To quash the virus, the immune system unleashes an arsenal. Sometimes these weapons turn inward and destroy healthy tissues. Combatting this friendly fire has become as crucial a part of the Covid-19 treatment strategy as subduing the virus itself. https://t.co/FrxVfSleEH

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https://nyti.ms/2GJZjd2

NYT Health NYTHealth ( View Tweet)

Oct 06, 2020

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Adam Cifu adamcifu ( View Tweet)

Oct 05, 2020

RheumNow Podcast – Function Follows Form (10.2.20)

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d Jack Cush, MD

Oct 01, 2020

Dr. Jack Cush reviews the news and journal articles from the past week on RheumNow.com. Regulatory approvals, update on global rheumatology alliance, smoking and psoriasis, gabapentin let down and defining difficult RA.

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Latest data Global Rheumatology Alliance COVID Registry -2121 pts (40% RA, 17% SLE, 9% PsA), 64% on DMARDs, 33% biologics, 5% JAKi, 34% steroid,27% HCQ, with only 7.6 deaths and 39% hospitalized and 81% resolved infection. https://t.co/g0w4QZHmRl

Links:

https://bit.ly/3cNNDSx

Dr. John Cush RheumNow ( View Tweet)

Oct 01, 2020

Swiss cohort of 666 axSpA, RA & PsA pts seen before, during & after COVID; consults dropped 52%, remote visits increased 129%, & non-compliance slightly increased during COVID (axSpA 20% vs 13% before, p=0.003); but no incr in flares(<15%) or Dz activity https://t.co/lWb7WCwGbN

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https://bit.ly/3cMZ1OK

Dr. John Cush RheumNow ( View Tweet)

Oct 01, 2020

Hydroxychloroquine Fails as Pre-exposure Prophylaxis for COVID-19

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d Jack Cush, MD

Sep 30, 2020

Numerous previous studies have questioned the efficacy or protection afforded by hydroxychloroquine (HCQ) for COVID-19 and studies have show that HCQ has failed when given as post-exposure prophylaxis to health care workers (HCWs). A new randomized controlled trial has shown that HCQ failed when given as 8 weeks of pre-exposure prophylaxis in hospital-based HCWs exposed to patients with COVID-19 patients.

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The RheumNow Podcast is up! Cardiovascular Risk in Psoriatic Disease, Higher COVID rates in young adults, Reimbursements for Rheumatologists and more. Watch here>> https://t.co/cBHTeUQhff or liste to podcast here> https://t.co/KBgmsoGRzU or on iTunes> https://t.co/FHJv01AAbC

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