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Patient Perspectives on Telemedicine Use During the Pandemic

Jack Cush, MD

Research from the COVID-19 Global Rheumatology Alliance included surveys and data gathering from rheumatology patients.

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Hold the Methotrexate for One Week

Jack Cush, MD

In 2018, Park et al showed optimal responses to influenza vaccination in RA patients was best achieved by holding methotrexate for 2 weeks following immunization, with improved humoral responses. Now, a followup trial suggests that equivalent results are had by holding MTX for only 1 week with the "flu" vaccine.

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RA Biologics Lower COVID-19 Deaths, but Not Recovery Time

Jack Cush, MD

Do abatacept, cenicriviroc, or infliximab improve time to recovery for patients hospitalized with COVID-19 pneumonia compared with standard care?

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What is Colchicine Worth? (6.23.2023)

Jack Cush, MD

Dr. Jack Cush reviews the news and reports from the past week on RheumNow.com. This week a new colchicine FDA approval, rising rate of IgG4 related disease and what's the safest biologic?

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Allergic Drug-Induced Arthritis (5.19.2023)

Jack Cush, MD

Dr. Jack Cush reviews the news and journal reports from this past week on RheumNow.com.  This week we delve into some odd associations, repeat drug warnings and the consequences of antirheumatic therapies.

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One in Ten is Bad! (5.12.2023)

Jack Cush, MD

This week on the Podcast Dr. Jack Cush reviews the news and journal articles, including the risks of dying, developing RA or autoimmune disease!

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2022 EULAR Recommendations on Screening and Prophylaxis for Opportunistic Infections

Jack Cush, MD

Opportunistic and chronic infections may be rare and are often difficult to diagnose, especially in patients with autoimmune inflammatory rheumatic diseases (AIIRD), that may be immunocompromised.

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Industry Payments to Rheumatologists Dropped During COVID

MedPage Today

Having their clinics shut down and patients staying away during the COVID-19 pandemic was bad enough for physicians' finances, but now a new study finds that, at least for rheumatologists, payments from industry dried up as well.

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While COVID rates are near historic lows & far less dangerous, hospitalizations are up 10.3%, ER visits up 7%, pos. tests rose to 6.3% from 5.8% in the last week https://t.co/TFAt4p24au

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Dr. John Cush RheumNow ( View Tweet)

RA Biologics Lower COVID-19 Deaths, but Not Recovery Time Do abatacept, cenicriviroc, or infliximab improve time to recovery for patients hospitalized with COVID-19 pneumonia compared with standard care? https://t.co/o56m9WumiC. https://t.co/GHe1RprDnk

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Dr. John Cush RheumNow ( View Tweet)
An RCT of 1136 newly COVID test positive pts compared long term outcomes if immediately given METFORMIN or Placebo. Cumulative incidence of long COVID at day 300 was 6.3% w/ metformin vs 10.4% w/ placebo (HR 0.59; HR 037 if given w/in 3d) https://t.co/aCTX7xFewW https://t.co/xbBeED9K7U

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Dr. John Cush RheumNow ( View Tweet)
Factors associated with higher prevalence of post COVID-19 condition include female sex, age, asthma, diabetes, hypertension, number of symptoms in the acute phase and possible mechanisms causing the syndrome, Mayssam Nehme, COVID-19, #EULAR2023 https://t.co/IzHEQqfPb1
Dr. Antoni Chan synovialjoints ( View Tweet)
Reflections on COVID-19 and autoimmunity: post-vaccination autoimmunity is not specific to COVID-19, autoimmunity is not autoimmune disease, the large numbers may result in the perception of increased occurrence of autoimmunity, Schulze-Koops H, COVID-19, #EULAR2023 @RheumNow https://t.co/Rm9OEWrBzo
Dr. Antoni Chan synovialjoints ( View Tweet)
Factors related to having a flare of arthritis during COVID-19 include female gender, higher disease activity, no DMARD at time of vaccination. Stopping DMARDs need to be weighed up against risk of flares, Pedro Machado, COVID-19 #EULAR2023 @RheumNow https://t.co/3sd32tF2kW
Dr. Antoni Chan synovialjoints ( View Tweet)
Lit review of 2236 articles found only 28 w/ Post-COVID autoimmune Dx (64% F; age 51 yrs) - that included 11 (39) IIM (w/ 4 DM); 7 (25%) SLE; 4 (14%) anti-synthetase syndrome; 4 (14%) SSc; 1 lupus/MCTD overlap. Mean onset 23.7 d post COVID https://t.co/jtRaqIBGH1 https://t.co/WilcRFNAL9

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Dr. John Cush RheumNow ( View Tweet)
in 2022 COVID slid from the #3 to the #4 cause of death in USA, accounting for nearly a quarter million deaths, a 47 percent decrease from the 462,193 Covid-related deaths in 2021. Most COVID deaths occured in the first few mos of 2022 https://t.co/qervCp0P87 https://t.co/WN7DvsFhNC

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Dr. John Cush RheumNow ( View Tweet)
COVID had a significant effect on mental health of inflammatory rheumatic Dz (IRDs) pts. UK NHS survey of 639 IRD (70% RA, 16% PsA) saw 40% w/ mod/severe pandemic impact on physical & mental health; 29% w/ depression, 22% anxiety; affecting Women>males https://t.co/kcAwa2Lks2 https://t.co/R6tk2aOrGQ

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Dr. John Cush RheumNow ( View Tweet)
Industry Payments to Rheums Dropped During COVID Having their clinics shut down and patients staying away during the COVID-19 pandemic was bad enough for physicians' finances, but now a new study finds that payments from industry dried up as well. https://t.co/jsxw23tTyY https://t.co/5PiaRpiSa4

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Dr. John Cush RheumNow ( View Tweet)

Anakinra Phase 2/3 study in severe hosp. COVID-19 pts (5/20-3/21) w/ pneumonia & hyperinflammation (incr levels IL-6, ferritin, CRP, LDH). 179 pt Rx w/ ANA or SOC - d15 need for Mech ventilation was 77% ANAK v 86% SoC (NS; RR 0.90; 0.77-1.04) https://t.co/CFcI1qTsU2 https://t.co/wAj4pHN5Dh

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Dr. John Cush RheumNow ( View Tweet)
Paxlovid (Nirmatrelvir-Ritonavir) should be used w/in 5d of COVID Sxs onset. Drug interactions include: steroids, anticoagulants (Eliquis, Xarelto, warfarin), Flomax, Calcium channel blockers, benzodiazepines. https://t.co/VZpS1z3OGR https://t.co/hR6JAJ3BBO

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Dr. John Cush RheumNow ( View Tweet)
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