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“Courage is what it takes to stand up and speak; courage is also what it takes to sit down and listen.”
– Winston Churchill https://t.co/5YMQppiMSG
Dr. John Cush RheumNow ( View Tweet)
Why DORIS or LLDAS #remission
🤔
⬇️mortality
⬇️damage
⬆️QoL
Dr Nikpour at On Rheum Assoc
Shows Remission > LLDAS
no pred ✅ best
@RheumNow https://t.co/tFcPrkd5Vd
Links:
Janet Pope Janetbirdope ( View Tweet)
🍋 or ‘Lyme’
- is it Lyme disease?
Dr Elizabeth Stringer discusses Eastern Canada 🇨🇦
Epidemic of #Lyme #arthritis
Which mimics #pauciarticular #JIA
When it is #chronic
Work up of all oligoarthritis in endemic areas in kids
Includes
Validated Lyme test
@ORAexec #ORA25 https://t.co/WxU1vaOa7z
Janet Pope Janetbirdope ( View Tweet)
Subclinical #arthritis in #SLE
Do we look for it?
Should we care?
Certainly seems to exist on #MRI hands
More changes of course if tender joints
Not sure of clinical relevance
Optical imaging and POCUS was compared
#LUPUS2025 @RheumNow
ANCA Askanase presents
Janet Pope Janetbirdope ( View Tweet)
Systematic review and meta-analysis confirms modest efficacy of infliximab for pulmonary sarcoidosis and promising but limited evidence for adalimumab, tofacitinib and efzofitimob in specific sarcoid manifestations. https://t.co/XaqSiAVQTa https://t.co/DTGbIiPT3a
Dr. John Cush RheumNow ( View Tweet)
Is Lupus Just a B Cell Disorder?
https://t.co/0kwxE6KLeI https://t.co/pORHkg9HY6
Dr. John Cush RheumNow ( View Tweet)
Neutrophil alkaline phosphatase (NAP) elevated in active AOSD. 141 AOSD compared to Bcell lymphoma, SLE, aPL & controls. NAP pos. correl w/ Systemic Dz activity score (R=0.71), & 0.59 for CRP/ANC/ferritin. NAP scores higher in pre-MAS, but lower w/ MAS (w/lower WBC). NAP responds https://t.co/YbYPaJUEbz
Dr. John Cush RheumNow ( View Tweet)
Panacea of Prednisone & Cannabis (5.16.2025)
Dr. Jack Cush reviews the news, journal and regulatory reports from this week on RheumNow. Interesting trends and results with prednisone in lupus, cannabis in RA and opioid deaths too!
https://t.co/QDtxItYSco https://t.co/s4nYmMe3vs
Dr. John Cush RheumNow ( View Tweet)
Vitiligo affects up to 2% of people globally; more in blacks & hispanics than whites & more common in women > men. The prevalence has increased over time. Oral corticosteroids are most frequently prescribed, followed by other immunosuppressive drugs https://t.co/wNh6z3lKg1 https://t.co/hQo9sNn4kg
Dr. John Cush RheumNow ( View Tweet)
Periprosthetic femoral Fx (PPFF): metanalysis of 36 studies found PPFF risk factors: Uncemented stems (OR 3.36), major teaching hosp (2.0), female (1.6), obesity (1.4), Hi comorbidity(1.4), RA (1.89), (1.67), revised THR (2.6). OA = protective (0.51) https://t.co/y2BpH8LUb6 https://t.co/EjX6R9QTK3
Dr. John Cush RheumNow ( View Tweet)
MTX works in pulmonary Sarcoid! NEJM reports Open label RCT of 138 un-Rx pulm. Sarcoid pts w/ either MTX or placebo. After 24 wks MTX was noninferior to PBO w/ mean change in FVC (-6.7 vs -6.1). AE: more Wt gain, insomnia w/ pred & more Nausea fatigue LFTs w/ MTX https://t.co/8XMCM2DitR
Dr. John Cush RheumNow ( View Tweet)
Lupus QD Clinic - Rhupus
dsDNA+ SLE Plus CCP+ RA = Rhupus
https://t.co/lyV7fgd1vp https://t.co/IKkS0enQH9
Dr. John Cush RheumNow ( View Tweet)
Periprosthetic femoral Fx (PPFF): metanalysis of 36 studies found PPFF risk factors: Uncemented stems (OR 3.36), major teaching hosp (2.0), female (1.6), obesity (1.4), Hi comorbidity(1.4), RA (1.89), (1.67), revised THR (2.6). OA = protective (0.51) https://t.co/y2BpH8LUb6 https://t.co/hX2lcjI4Kg
Dr. John Cush RheumNow ( View Tweet)
SLE Perspectives: Past, Present, Future
https://t.co/ggYmVvEtZx https://t.co/VriDjAEcl5
Dr. John Cush RheumNow ( View Tweet)
Risk Factors for Knee Osteoarthritis
New research from the University of Sydney reveals that obesity, having a knee injury and occupational risks such as shift work and lifting heavy loads are primary causes of knee osteoarthritis.
https://t.co/Kc686Zc8Xa https://t.co/ANyiE2pIxo
Dr. John Cush RheumNow ( View Tweet)
3-year, RCT of Mediteranean diet vs usual care in 924 older adults w/ metabolic syndrome & BMI > 27. Med. diet shows signif wt loss (3.4% vs 0.4%), w/ improved BMD (by DEXA) at year 3, especially in women. https://t.co/mllx6l1QnM https://t.co/I5e8PXX2oX
Dr. John Cush RheumNow ( View Tweet)
A brief history of familial Mediterranean fever - FMF is most common periodic fever syndr. an inherited polyserositis mainly affects Arabs, Armenians, Jews, & Turks. Hx may date back to 1802 & Heberden. Osler described 11 cases in 1895. 1st clear report 1945 by Siegal 10 pts. https://t.co/m20uO3bOoj
Dr. John Cush RheumNow ( View Tweet)
Lessons Learned from a Lupus Registry: Two sides of one coin?
It's Dr. Janet Pope reporting at RheumNow on our special lupus edition. I'd like to talk about lessons learned from a Canadian lupus registry. Is it two sides of one coin?
https://t.co/IxMZhA1uht https://t.co/PJixCj8d6g
Dr. John Cush RheumNow ( View Tweet)
CDC: U.S. Overdose Deaths Decrease Almost 27% in 2024, dropping from 110,037 deaths (2023) to ~80,391(2024). Despite these improvements, overdose remains the leading cause of death for Americans aged 18 to 44. https://t.co/UXTaOPf3P7 https://t.co/1NQUfoZ1eK
Links:
Dr. John Cush RheumNow ( View Tweet)
Is the nosology of CPPD outdated? Pseudogout to chondrocalcinosis? In 2011 EULAR taskforce rec the preferred term "calcium pyrophosphate deposition dz". G-CAN aims to update & standardised terminology for CPPD, requiring change to ICD-10 & adoption by societies https://t.co/mdqwDQN1po
Dr. John Cush RheumNow ( View Tweet)


