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Dr. Pascual shows that signatures show IFN or plasmablast or PMN/Myeloid signatures, thus identifying 7 subsets of lupus kids #UTSWSLE2022 https://t.co/3BAxPdAKw8
Dr. John Cush RheumNow ( View Tweet)
DOCTORS: are you ready to attend big medical meetings ? @LCalabreseDO
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Clinical evidence of type I IFNa excess expressed in clinical SLE (Dr. Virginia Pascual) #UTSWSLE2022 https://t.co/To2U9ZtxU3
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Professor Chandra Mohan on pathogenesis and immunogenetics of #SLE - over 180 genes linked to the pathogenesis, modified by infection (bigger role for EBV?) hormones, smoking, hormonal status. #UTSWSLE2022 https://t.co/aKNpxZfdc6
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Efficacy of Subsequent b/tsDMARD Use in Rheumatoid Arthritis
https://t.co/5dXe0AdNzE https://t.co/eS4KdaKBmC
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Three (3) Worst Drugs to use in #Lupus patients who want to be pregnant (MTX, MMF, CTX) #UTSWSLE2022 https://t.co/YBeLTuRLO1
Dr. John Cush RheumNow ( View Tweet)
Algorithmic approach to SLE and assessing/treating early pregnancy. #UTSWSLE2022 https://t.co/692el4R9sZ
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Adverse pregnancy outcomes and Risks in #SLE. (Dr. Eliza Chakravarty - OMRF) #UTSWSLE2022 https://t.co/HqscJD2m96
Dr. John Cush RheumNow ( View Tweet)
Long acting reversible contraceptives (LARC) are recommended in #SLE. #UTSWSLE2022 https://t.co/oFyNTHzVAj
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Nearly 40% of all #SLE pregnancies are unplanned - hence, contraception (unused in 73%) and education are paramount in management of women w/ SLE. (Dr. Lisa Sammaritano- HSS) #UTSWSLE2022 https://t.co/ooryrW9GGn
Dr. John Cush RheumNow ( View Tweet)
An increasing incidence of RA is driven by increasing # of ACPA-negative RA (but not ACPA-positive RA), partly explained by an ageing population (thus making ACPA-negative RA more prevalent in coming years) https://t.co/9vC8aCphKc
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"I think we can get rid of maintenance prednisone in nonrenal lupus" (but not in renal lupus)
"...prednisone contributes to some organ damage (but not renal)"
Organ damage is multifactorial -traditional risk factors, disease activity & steroids
- Dr. Michelle Petri #UTSWSLE2022 https://t.co/N9NMPgtPEn
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"How awful is our current prednisone practice"
- Dr. Michele Petri #UTSWSLE2022 https://t.co/WGNx5yxF8x
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From the Hopkins Lupus cohort - Just one month of Prednisone 40 mg/d yields a FOUR fold increase in avascular necrosis risk #UTSWSLE2022 https://t.co/RGP06PUIKH
Dr. John Cush RheumNow ( View Tweet)
DOCTORS: are you ready to attend big medical meetings ? @LCalabreseDO
Dr. John Cush RheumNow ( View Tweet)
Large Korean population study compares pts w/ palmoplantar psoriasis vs psoriasis and PPP pts have more risk for ankylosing spondylitis (aOR 1.37) & Graves dz (aOR 1.4) but lower risk for PsA (aOR 0.54), SLE (0.67); Sjögren (0.70); vitiligo (0.53) https://t.co/0fv2vnFBPf https://t.co/PJMagIeZ2F
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UT Southwestern Symposia on "Future of SLE". Summary of Disparities in SLE Care/Outcomes (from Dr. Candace Feldman - Harvard). #UTSWSLE2022 https://t.co/KQb9JV7uJU
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Yet another examples of underrepresentation of minority groups in clinical trials! #UTSWSLE2022 https://t.co/TbhhdglJ6v
Dr. John Cush RheumNow ( View Tweet)
How do we solve/address the problem of Health Disparities in Lupus and Rheumatology? Dr. Ashira D Blazer, MD @ashira_md (HSS) approach:
Study
Listen
Educate
Partner
Diversity
#UTSWSLE2022 https://t.co/w3DX1w0chy
Dr. John Cush RheumNow ( View Tweet)
Danish case-control registry of 491,274 women shows Psoriasis assoc w/ increased risk of ectopic pregnancy (EP) (OR 1.34), highest in women w/ moderate-to-severe psoriasis (OR 2.77). EP risk was 2.5x higher for women w/ mod--severe PSO https://t.co/vUtNEMDOhr
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