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Dr. Kirkman reviews IL12, IL23, and IL17s. #RNL2022 @RheumNow https://t.co/nFHBzrdz2D
Dr. Rachel Tate uptoTate ( View Tweet)
Excellent graphic on mechanisms of action of PsA and their effects on specific cytokines
@RheumNow #RNL2022 https://t.co/B0ZT6qlpbE
Robert B Chao, MD doctorRBC ( View Tweet)
Use questionnaire if you sense something is not right!!
Bruce Kirkham @RheumNow #Rnl2022 https://t.co/tuBZiA7Dqf
Nouf Al hemmadi NoufAhmedAlham2 ( View Tweet)
T rm cells
▶️Found in skin and joint.
▶️Found in skin and Joint
▶️Unregulated easily in case of inflammation
▶️Releases IL17
▶️Specific role in PSA
Bruce Kirkham @RheumNow #Rnl2022 https://t.co/apFXhzIpFo
Nouf Al hemmadi NoufAhmedAlham2 ( View Tweet)
We always want Real World Data (RWD) but where does this come from? Dr. @AlexisOgdie reviews RWD and RWE (evidence) which "ideally reflects patients we actually see in clinic." #RNL2022 @RheumNow https://t.co/KLJlQ6wzqC
Dr. Rachel Tate uptoTate ( View Tweet)
Enthesitis in PsA is multi-faceted.
Environmental triggers, microbiome, microdamage in combination with innate immune response in genetically susceptible patients can active the IL-23 and IL-17 pathway
Leading to cartilage damage and degradation
@RheumNow #RNL2022 https://t.co/hvkCmJ0V1S
Robert B Chao, MD doctorRBC ( View Tweet)
PSA management:
MTX can be used alone
TNF and MTX are more effective
Other agents
Bruce Kirkham @RheumNow #Rnl2022 https://t.co/rgdylgYDSb
Nouf Al hemmadi NoufAhmedAlham2 ( View Tweet)
Get the skinny on THIN. Large EMR database in UK with real world evidence #RWE in #PsA. #Psoriatic arthritis. Teaches about safety, drug retention & comparative effectiveness. Latter is a problem as loss of retention could be ineffective, side effects A Ogdie #RNL2022 @RheumNow https://t.co/V1mYiE3GbI
Janet Pope Janetbirdope ( View Tweet)
This is important in real world practice #RNL2022 https://t.co/YSJgx3QxVx
madan madanpadmajan1 ( View Tweet)
#RNL2022 the true hybrid conference since "before hybrid was cool." @RheumNow @AlexisOgdie @RWCSmtg Dr. B. Kirkham joining us live and by Zoom. https://t.co/6BaYSMFjsR
Dr. Rachel Tate uptoTate ( View Tweet)
RWE (real world evidence) helps in informed disease decisions!! Very interesting!!!!!
@AlexisOgdie @RheumNow #Rnl2022 https://t.co/Pyv2KJz3uO
Nouf Al hemmadi NoufAhmedAlham2 ( View Tweet)
Dr. @AlexisOgdie reminds us the RWE informs tx decisions, methods matter (so review these!), tx outcomes and disease subsets in the real world are important and we need to fill in gaps! #RNL2022 @RheumNow https://t.co/O4ni5EnZmr
Dr. Rachel Tate uptoTate ( View Tweet)
#ClinicalPearl #psoriatic arthritis arthroscopy show cork screw angiogenesis in knee. Active disease w 😜 wild vasculature. Bruce Kirkham also worked on IL17a w several drugs now if #IL17 inhibitors @RheumNow #RNL2022 https://t.co/Hr04RDGD6F
Janet Pope Janetbirdope ( View Tweet)
Larger than life! Experts virtually present and live at #RNL2022 in panel discussion with Jack Cush moderating discussion with Drs Kavanaugh, Kirkham & Ogdie. Noting often response to #PsA Rx is different on skin, joints & PROs. yes virtual presenters 👀 like giants in the field https://t.co/XBgDtihRmq
Janet Pope Janetbirdope ( View Tweet)
Dr. Peter Lipsky on the "Almighty ANA"
"There are 45 million people out there with a +ANA. It is not a good screening tool."
@RheumNow #RNL2022 https://t.co/Xtu7kUzd6K
Robert B Chao, MD doctorRBC ( View Tweet)
Dr. Kavanaugh reviews the 2018 ACR/National Psoriasis Foundation PsA treatment guidelines. #RNL2022 @RheumNow @RWCSmtg https://t.co/AI3kL6HGxr
Dr. Rachel Tate uptoTate ( View Tweet)
Pathogenesis of RA and PSA
Bruce Kirkham @RheumNow #Rnl2022 https://t.co/YKACWyUkFQ
Nouf Al hemmadi NoufAhmedAlham2 ( View Tweet)
EULAR 2019 PsA treatment recommendations. Dr. Kavanaugh #RNL2022 @RWCSmtg @RheumNow https://t.co/3yncNY59OW
Dr. Rachel Tate uptoTate ( View Tweet)
New GRAPPA Guidelines , Cant wait for the final draft to be released!!
They added other associated features like IBD and eye involvement as well as comorbidities!! cool stuff🤓 smart move.
Arthur Kavanaugh @RheumNow #Rnl2022 https://t.co/CYfEc8j4xX
Nouf Al hemmadi NoufAhmedAlham2 ( View Tweet)
GRAPPA: the 2015 guidelines and the initial draft (still in revision) of the purposed 2021 guidelines. Dr. Kavanaugh We've been busy getting approved treatments options for our PsA patients over the past few years!
@RWCSmtg #RNL2022 @RheumNow https://t.co/CJGrNbg6MA
Dr. Rachel Tate uptoTate ( View Tweet)