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#ACR21 Abs#1915
👉🏼Chronic steroid use in older adults on stable DMARD therapy
assoc w/ ⬆️CV risk
👉🏼Risk even present among older adults receiving low dose ≤5mg/day
👉🏼Larger studies needed in younger healthier adults
@RheumNow https://t.co/Lsj5YBz7IG
Mrinalini Dey DrMiniDey ( View Tweet)
Congratulations @KenSaag the 85th President of @ACRheum Under your guidance we will flourish as a team that “is there for our members so they can be there for their patients”. #ACR21 #RheumatologyIsAmazing
David Karp DrDavidKarp ( View Tweet)
#ACR21 2022 ACR/EULAR TAK Criteria
▶️Classification, NOT diagnostic!
⭐️Must be <60 yo, needs vasculitis on imaging
⭐️Clinical criteria + imaging finding (more points for more arteries, 3 pt for abd aorta with renal or mesenteric involvement)
@RheumNow https://t.co/6YWmabNzuH https://t.co/fJka2a9tqm
Links:
Eric Dein ericdeinmd ( View Tweet)
HCQ adherence (>90%) associated with 52% reduced cardiovascular mortality in RA and SLE. Seen for MI, stroke, not VTE. Abstr#1909 #ACR21 @RheumNow https://t.co/5UncmqZVNp
Richard Conway RichardPAConway ( View Tweet)
Long-term low dose glucocorticoid use associated ⬆️cardiovascular risk. Clear effect in Medicare population (older), not evident in Optum (younger). Dose dependent. Abstr#1915 #ACR21 @RheumNow https://t.co/oFet3Hhsfo
Richard Conway RichardPAConway ( View Tweet)
Claims data looked at 21,114 #RA & #SLE pts - 4.3% had CV Death. The risk of CVD was worse w/ HCQ nonadherence (HR 1.08; 0.91-1.31) and better w/ HCQ adherence (HR 0.51;0.42-.66) HCQ nonadherence shows higher CV mortality #ACR21 Abst# 1909 https://t.co/di1mBliMN6
Dr. John Cush RheumNow ( View Tweet)
Retrospective cohort study FORWARD databank :
⭐️ 🔼opioid use was associated with higher HAQ-DI and BASDAI scores among patients with PsA or AS
Annualized avg opioid use and costs 🔼with 🔼HAQ-DI and BASDAI scores for patients in both cohorts
Abst#1117 #ACRBest @RheumNow https://t.co/KB9QUITbAe
swethaann23 swethaann23 ( View Tweet)
#ACR21 TM18
⭐️Spontaneous coronary artery dissection (SCAD) of LAD
▶️ +Sicca, Photosensitivity, malar erythema, alopecia, oral ulcers, arthralgias
▶️ ANA negative, dsDNA HIGH
Rare case of ANA negative SLE with odd presentation!
https://t.co/jfmVtZ4iOV @RheumNow https://t.co/pMHcColeUn
Links:
Eric Dein ericdeinmd ( View Tweet)
SpA & Pregnancy Outcomes?
➡️SpA pts txed w/ bDMARDs at conception are not at higher risk for adverse pregnancy outcomes compared to those w/o bDMARD
➡️Stopping bDMARDs after conception assoc w/ ↑ dz activity during pregnancy + after birth & ↑flares
Abst#1730 #ACR21 @RheumNow https://t.co/Y4c7vI0cgS
Meral K. El Ramahi, MD MeralElRamahiMD ( View Tweet)
#ACR21 Thieves TM17
Fascial and muscle edema + ecchymoses + petechiae
❌🥝🍎🥦🍅 in diet
A: Scurvy
⭐️Skin exam with ecchymoses, corkscrew hairs are your clues!
@Rheumnow https://t.co/AUvme7aeDn https://t.co/4crnYzxfc7
Links:
Eric Dein ericdeinmd ( View Tweet)
60% don’t use pneumocystis prophylaxis #PJP in #lupus #SLE @RheumNow #ACR21 https://t.co/AVf97xJhtL
Janet Pope Janetbirdope ( View Tweet)
Use of #rituximab is same in Rheum pts during #COVID19 says 1 in 3 #rheumatologists but less use say 60%! #ACR21 @RheumNow https://t.co/ginurWvkOC
Janet Pope Janetbirdope ( View Tweet)
Press Conference Arthritic Disease
Abs 1451
Ologhobo & colleagues examined impact of virtual exercise program in individuals w/ MSK conditions
Members reported decrease in
- Pain
- Pain interference
- Fatigue
- Stiffness
#ACR21 @RheumNow https://t.co/T5qdlLEYZ0
Akhil Sood MD AkhilSoodMD ( View Tweet)
Top Influencers of #acr21: @ACRheum @rheum_cat @RheumNow @CreakyJoints @RichardPAConway @KDAO2011 @alhkim More 📊 https://t.co/vyMAwjKbqC
Symplur Hashtags healthhashtags ( View Tweet)
*️⃣Abst#1800 observed that a changing pattern of purine, lipid, & amino acid metabolites occurred during transition from PsO to PsA.
*️⃣Compared to pts w/ Pso that didn't progress to PsA, those that progressed had elevated levels of guanine!
Potential biomarkers?
#ACR21 @RheumNow https://t.co/iQh1ZapDMB
Meral K. El Ramahi, MD MeralElRamahiMD ( View Tweet)
Dementia is ⬆️in #RheumatoidArthritis says Elena Myasoedva but #RA has more DM &CV disease which ⬆️dementia. Need to separate vascular dementia from Alzheimer’s. When I trained we thought less dementia in RA -likely not true. More work is coming. 9T213 aging hub #ACR21 @RheumNow
Janet Pope Janetbirdope ( View Tweet)
Post-Hoc of the ASCORE trial showed the following b/l characteristics were most likely associated with remission (per DAS28, SDAI, CDAI) in mod-severe RA patients treated w/ SQ Abatacept:
⭐️Seropositivity
⭐️no prior bMDARD use
⭐️low HAQ-DI
⭐️low BMI
Abst#1228 #ACR21 @Rheumnow https://t.co/NvJoSWScZs
Meral K. El Ramahi, MD MeralElRamahiMD ( View Tweet)
⭐️Immune phenotyping of 45 patients with Pso and 41 PsA pts showed a number of cell subsets significantly different in Pso vs PsA
⭐️Future possibility of using a combination of selected immune cell subsets as a method for detecting PsA in Pso pts
Abst#1774 #ACR21 @Rheumnow https://t.co/ER1MPOvMa6
swethaann23 swethaann23 ( View Tweet)
#ACR21 #AbstrL17 In pts treated with Rituximab, arrange a 3rd primary dose ASAP regardless mRNA or vector #COVID vaccine. An RCT of N=60 pts who did not seroconvert after primary dose, overall 94% either seroconverted/new T-cell response @RheumNow #ACRBest https://t.co/F15j93OFE4 https://t.co/tXoisoYthx
Md Yuzaiful Md Yusof Yuz6Yusof ( View Tweet)
Abst#1774 identified a blood-based immune profile with a machine-learning approach that discriminates PsA from Pso.
➡️↑ proportions of differentiated CD4+CD196+CD183–CD194+ and CD4+CD196–CD183–CD194+ T-cells in PsA
#ACR21 @RheumNow https://t.co/64uhJCd2qo
Meral K. El Ramahi, MD MeralElRamahiMD ( View Tweet)