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Supporting date for Ixekizumab in PsA with symptoms of axial involvement.
🔹Improvement in QoL (SF-36), ASDAS, BASDAI50
🔹Maintained at 52 weeks
🔹Stricter criteria (younger, ⬆️CRP) showed similar results
https://t.co/QSJLQTxLcW
#ACR21 Abst#3147
@RheumNow
Pedro Castillo _Castillo_Pedro ( View Tweet)
Calcium hyperproficiency is a rare complication of vitamin D deficiency, where excess calcium from bone resorption forms complex structures resembling primary teeth.
Neoformed teeth grow on different bones, such as this patient's hand, causing fractures and joint dysfunction. https://t.co/oGYCYkh1WD
Eduardo Valdés-Hevia 🦟 Valdevia_Art ( View Tweet)
Adults with #JIA #uveitis are still affected into adulthood. @Mara_Becker discusses visual outcomes #ACR21 https://t.co/ZBjw1CfSmv
Sheila Angeles-Han STHanMD ( View Tweet)
#ACR21 L06 Comparative Safety of Gout "Treat-to-target" and "Usual Care" Treatment Strategies on Cardiovascular Outcomes Using Observational Data: Causal Inference Approach https://t.co/4qo49lpBrt Video interview (https://t.co/k8PHCPaF1r) https://t.co/D4G2Ylkelm
Links:
Kazuki Yoshida kaz_yos ( View Tweet)
🆕 Updated 2021 ACR Guidance for Adjusting Immunomodulatory Therapy with the COVID-19 Vaccine in Patients with Rheumatic & MSK Diseases
Discussed at #ACR21 COVID-19 Hub!
V4 Link: https://t.co/1SOR9yTQyF https://t.co/PKFKXpLofN
Links:
Mithu Maheswaranathan, MD MithuRheum ( View Tweet)
Prof. Cornelia Weyand wonderfully summarizes the mechanisms behind the premature immune #aging phenotype in #RheumatoidArthritis leading to tissue #Inflammation
🔸defect in mitoDNA repair
🔸expanded rough ER
🔸⬇ protein myristoylation
@RheumNow #ACR21 #RheumTwitter https://t.co/8cyqLscctB
sheila RHEUMarampa ( View Tweet)
Can you stop monitoring eyes in + ANA and/or pauciarticular pt who becomes an adult if no uveitis ever, in last 5 yrs, etc. When can we stop looking? #AVR21 @RheumNow https://t.co/1Ml1BuJD7Y
Janet Pope Janetbirdope ( View Tweet)
Telemedicine for AID patients! A fortunate pandemic outcome that PCPs shared "local" care benefit of specialists for these patients due to telemed. Abs 1062 #ACR21 @RheumNow #RheumNow https://t.co/zb0kZbzxsK
Dr. Rachel Tate uptoTate ( View Tweet)
Very high serum IgG4 does not equal IgG4-related disease.
Most of the time (3/4 in this sample), IgG4>5xULN is IgG4-RD.
Some of the time, it's not. (Could be a long list of things)
Criteria are useful
High serum IgG4 alone isn't enough
@zach_wallace_md #ACR21 ABST1103 @RheumNow https://t.co/oxMgnnpIce
David Liew drdavidliew ( View Tweet)
Did you know?🤔Immune #aging:
🔖Begins at 20y and accelerates at 50y
🔖Species-specific
🔖The older immune system is restructured (keep that in mind when diagnosing or treating these pts)
🔖Accelerated w/ chemotx, chronic infection etc.
@RheumNow #ACR21 https://t.co/bgbN3VKMCw
sheila RHEUMarampa ( View Tweet)
#ACR21 Year in Review. Caielli et al. showed in some patients with #lupus, red blood cells retained their mitochondria (Mito+ RBCs) and their frequency correlated with disease activity and blood⬆️IFN @RheumNow https://t.co/ZixgAbOWJ0 https://t.co/hkTWE4m7Ph
Links:
Md Yuzaiful Md Yusof Yuz6Yusof ( View Tweet)
#ACR21 Year In Review highlighted the need to combat the root causes of socioeconomic disparities to improve functional status in #rheumatoid #arthritis @RheumNow https://t.co/MKgh7UEP8b https://t.co/Vg2jyfuDnf
Md Yuzaiful Md Yusof Yuz6Yusof ( View Tweet)
#ACR21 Year In Review: Factors associated with #COVID deaths in pts with #RMD:
⛔️age, male, HTN/CVD, lung disease, steroid>10mg/d, ⬆️disease activity
⛔️RTX (OR: 4), SFZ (3.6), other IS (2.2), No DMARDs (2.1) vs MTX monotherapy as reference @RheumNow https://t.co/Zd6qXCtGLk https://t.co/YHBEelLqKB
Links:
Md Yuzaiful Md Yusof Yuz6Yusof ( View Tweet)
#Abstr0076 #ACR21 Can we predict #thrombosis in #lupus patients? Predictors of serology transition at 5yrs:
✅LAC+ to LAC-:Afro-American,HCQ and normal C3
⛔️LAC+ to 🩸Clot:Obesity, low C3 and not on HCQ
Data need in those with Triple Positivity @RheumNow https://t.co/byeL5NjVUS https://t.co/CchtZir2GN
Md Yuzaiful Md Yusof Yuz6Yusof ( View Tweet)
#Abstr0002 #ACR21 What drives salt in saliva in #sjogren? A study suggested Bcell cytokines mediated the epithelial Na+ Channel disruption. A case for targeting Bcell to improve oral health @RheumNow https://t.co/Bx3kBpOIFX https://t.co/YYnC6UoMJY
Md Yuzaiful Md Yusof Yuz6Yusof ( View Tweet)
Either we need to review the Yearly PAP cervical screening in SLE women or work hard to improve patient awareness. Suspect the latter as time between tests was over 4 years late 😱 and 2.7% developed cancer #ACR21 #Abstr0133 @RheumNow https://t.co/wm01MfoFjf https://t.co/blD8WafZsE
Md Yuzaiful Md Yusof Yuz6Yusof ( View Tweet)
#ACR21 #Abstr0454 Mortality rate in #lupus nephritis ⬇️by 26% from 1999-2019👏. BUT, racial and residence disparities were concerning; worse in Black, Hispanic, Asian, AI/AN vs White and in large central and medium metro. Residential matters! @RheumNow https://t.co/33vN39acuL https://t.co/XMwN2hXJn7
Md Yuzaiful Md Yusof Yuz6Yusof ( View Tweet)
#ACR21 #Abstr0768 We need to improve disparity among all levels of income. Support to the lowest income group seemed to improve but children with #lupus who were in the 2nd level income quartile had the longest length of stay in the hospital #RheumNow https://t.co/7HSveerUhs https://t.co/cSQBELopH5
Md Yuzaiful Md Yusof Yuz6Yusof ( View Tweet)
A very strong and inspirational opening session quote "Create new better normal where you can create systems that are resilient to a crisis and the foundation trend towards paradigm shift after what the pandemic has brought to light the gaps" #ACR21 #RheumNow @DoctorYasmin https://t.co/Ikbt9LiPwu
swethaann23 swethaann23 ( View Tweet)
@DoctorYasmin: "Let's talk about the history ... let's build bridges." We individualize approach to treatments, we should also individualize our conversation about vaccine hesitancy to your patient's specific concerns. @rheumnow #ACR21 https://t.co/1Jxw8l2phB
Eric Dein ericdeinmd ( View Tweet)