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A longitudinal, multinational study shows that SLE patients achieving remission or low disease activity incur lower overall direct/indirect (DCs, ICs) healthcare costs than those with persistent activity.
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A systematic review of randomized clinical trials of patients with biopsy-proven lupus nephritis (LN) demonstrates both the benefits and harms to early glucocorticoid (GC) regimens on lupus outcomes.
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Infectious conditions are a significant cause of mortality in autoimmune rheumatic diseases (ARD). Among patients hospitalized with an infection, we compared in-hospital and long-term (3-year) mortality between those with and without ARD.
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A metanalysis of randomized controlled trials (RCTs) on treatments of systemic lupus erythematosus (SLE), confirm the efficacy of several targeted small-molecule drugs.
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In a new study, researchers from Johns Hopkins Medicine say they have uncovered insights as to the relationship between interferons and lupus, which affects up to 1.5 million Americans.
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A metanalysis shows that social determinants of health adversely impacts patients with lupus nephritis. Lupus nephritis is a significant complication of SLE, often with dramatic increases in morbid and mortal risks. Outcomes are likely to be augmented by social determinants of health, including socio-economic status, and social risk factors.
Dr. John Cush
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Small-molecule Drugs to Treat Systemic Lupus Erythematosus
A metanalysis of randomized controlled trials (RCTs) on treatments of systemic lupus erythematosus (SLE), confirm the efficacy of several targeted small-molecule drugs.
https://t.co/O3Y3KBngau https://t.co/wiB1EMtMFK
Dr. John Cush
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Interferons and Lupus Subsets
In a new study, researchers from Johns Hopkins Medicine say they have uncovered insights as to the relationship between interferons and lupus, which affects up to 1.5 million Americans.
https://t.co/Eo8q3IGPb7 https://t.co/gVyHJwZFwc
Dr. John Cush
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Save the date! We’ll be covering #EULAR24! https://t.co/HGjP2SFyOp
Donald Thomas, MD
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10 Lupus Tips on May 10 (World Lupus Day) by @LupusMore
https://t.co/mON5ZyTpUE
#lupus #SLE #LupusAwarenessMonth
Laurent ARNAUD
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✅ Holistic #Lupus Management in 2024 👍 #LupusAwarenessMonth https://t.co/RY6AcHS9WQ
Dr. John Cush
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Multiplicative Adverse Effects of Social Determinants of Health in Lupus Nephritis: A Meta-analysis and Systematic Review
https://t.co/C6G3VePklU https://t.co/zVoLeI8ZxA
Dr. John Cush
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ICYMI: Tuesday Night Rheumatology- Mastering SLE
This webinar will feature highlights from these lectures followed by live audience Q & A
https://t.co/CLJbtvJKOT https://t.co/hGSK4P7NlF
Dr. John Cush
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CD19 is not expressed on Plasma Cells or Plasmacytoid dendritic cells. Yet, Selective CAR-T cell mediated B cell depletion suppresses interferon signature in SLE !! https://t.co/3DsonHZiWp https://t.co/dk5ZtQRnOm
Dr. John Cush
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SLE Faculty Panel Q&A
https://t.co/2OWlhfmKaP https://t.co/jx6MPDtojS
Dr. John Cush
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FDA issued a drug safety warning linking thiopurine (AZA, 6MP) use in pregnancy & a rare risk of intrahepatic cholestasis of pregnancy (ICP). ICP has been reported in pts w/ CD, UC, or SLE; however thiopurines are not FDA approved for these Dx https://t.co/s37eRuAtQx
Dr. John Cush
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Very late onset Lupus (>60) is less female, less arthritis/dz activity, lower dsDNA, C3, SSA, SSB and ANA but more Sjogrens & RA? Single clinic study of 845 SLE - jSLE (<18), aSLE (18-49), lSLE (50-60), and vlSLE (>60).vlSLE had lowest survival (20yrs) https://t.co/VwDSArDhrc https://t.co/3pSr0xSCKn
Dr. John Cush
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“50% of pts with lupus nephritis are asymptomatic . You have to have a degree of kidney damage before you have proteinuria. Proteinuria does not correlate with intrarenal activity.” – Dr. A Fava #RNL2024 @rheumnow https://t.co/w6UktVozsj
Dr. John Cush
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Full-read Overview of Macrophage Activation Syndrome - a rare complication of autoimmune inflammatory rheumatic dz; assoc w/ Still’s disease SLE, Kawasaki, dermatomyositis, RA, Sjögren’s. Precipitating factors, including genetics & infections reviewed https://t.co/LmL3BPmo6c https://t.co/OkfwpzNLAL
Dr. John Cush
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"Clinical Pearl!
Lupus flare mimics with Dr. Kahlenberg
- FM
- Stress
- Infection
- Lack of sleep
- Iron deficiency
- Vitamin D deficiency
- Celiac or other concomitant inflammatory disease
- thyroid issues
@Kahlenberglab #RNL2024 https://t.co/byNpSPuzC0"
