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Cardiovascular Prevention Lacking in Rheumatoid Arthritis

d Jack Cush, MD

An increased cardiovascular disease (CVD) risk in rheumatoid arthritis is well known and feared but an RA cohort study suggests that preventive medication use in RA patients lags behind that seen in diabetes mellitus (DM).

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COVID infection mask

CDC Reverses Stance on Masks

d Jack Cush, MD

Today the Centers for Disease Control and Prevention (CDC) said that masks should be used by those vaccinated against the coronavirus in public indoor spaces in parts of the country where the virus is surging.

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US News & World Report Ranks Best Rheumatology Hospitals

d Jack Cush, MD

Medscape has published the annual U.S.

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Rheumatoid Poor Outcomes Not Linked to Comorbidity

d Jack Cush, MD

Disease activity leads to poor outcomes; but does comorbidity add to this?  A recent analysis suggests that while comorbidities do not affect long-term, functional outcomes, sociodemographic factors do affect outcomes in rheumatoid Arthritis (RA).

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syringe, pill, DMARD, Treatment, therapy

DMARD Effects on COVID-19 Outcomes

d Jack Cush, MD

Sparks and colleagues have published data from the Global Rheumatology Alliance noting that among rheumatoid arthritis (RA) patients afflicted with COVID-19 infection, there was little influence of their baseline biologic or targeted synthetic (b/ts) disease-modifying antirheumatic drug

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Persistence of Sxs & Labs long after COVID. German study of 96 postCOVID pts followed 12 mos only 22% were Sx-free; Most had fatigue (53%), dyspnea (37%), concentration (40%), CNS (32%) & sleeping problems (26%), +ANA ≥1:160 in 44% https://t.co/L2ZzniDT18

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204 pts w/ dermatomyositis/polymyositis Rx w/ IV early pulse steroids(IVMP) or IVIG. IVMP & IVMP+IVIG was assoc w/ 56-58% incr odds of complete response. Pulse IVMP+IVIG incr risk of steroid D/C. Early IVMP/IVIG=no impact on mortality https://t.co/yRFJgos8Qq

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Bariatric surgery result in less pain med use. UK THIN database study of 588,494 pts: the 694 w/vbariatric surgery had a 23% increased odds of no analgesic use for ≥12 mos (HR=1.23) & all-cause mortality was also lower (HR=0.46) than controls https://t.co/b90AOE7lfg

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Claims data analysis of US Adult Medicaid patients shows and association between PTSD and increased risk of #SLE. 10K SLE compared to >100K controls. Prevalence of PTSD was significantly higher in SLE (10.74 vs 7.83 per 1000 (adj OR 2.0) https://t.co/p9F5iYENAu

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Dr. John Cush RheumNow ( View Tweet)

CMAJ: nice full read review of biologic use during pregnancy. 1) autoimmune/arthritis pts may use biologics during pregnancy 2) mom/infant should avoid live vax 1st 6–12 mos 3) Minimal biologic transfer in breast milk 4) no risk of congenital anomalies https://t.co/mlZTrDjXSi

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Top 10 things you should know about THE EYE in your rheumatology practice @CRASCRRheum #uveitisclinic #uveitisrheumatologyclinic #kensingtoneyeinstitute https://t.co/SqRKOYa2N0
Vanessa Ocampo - MD DrDDRheum ( View Tweet)
Another report of JAK inhibitor working in GVHD - Successful treatmente of joint & fascial involvement in GVHD with baricitinib. https://t.co/TQlPLCD2T7 https://t.co/474GpFKBo2

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New ACR Rheumatoid Arthritis Guideline: Emphasis on Methotrexate The ACR has issued new guidelines on the treatment of RA, addressing questions about initial treatment with methotrexate and minimizing reliance on glucocorticoids. https://t.co/J9wmcZr17D https://t.co/Tf3G9sFgm9

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Former Rheumatologist Settles Civil Fraud Claims for $2 Million for alleged False Claims Act violations. Charges were based on claims for improper medical treatments and false billing to a federal program. https://t.co/HZwrwDrkVk

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ICYMI: Neuropsychiatric Events Common in Lupus Neuropsychiatric (NP-SLE) or CNS lupus events range from mild to severe; several recent studies have noted that NPS lupus is common and should be screened for. https://t.co/cBDZI8OLKD https://t.co/on4fA3P9GS

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Fracture Risk with Low Dose Steroid A large RA cohort analysis shows that low-dose glucocorticoid therapy in rheumatoid arthritis (RA) patients may carry an increased risk of vertebral osteoporotic (OP) fractures. https://t.co/HcYpx8IDcB https://t.co/iVPjJHLNBX

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Dr. John Cush RheumNow ( View Tweet)
Recent review of the epidemiology of rare Autoimmune Liver disease (PBC, PSC, AIH) shows prevalence (per 100 000) to( vary for PBC (1.91 to 40.2), for PSC (0.78 and 31.7) and for AIH (4.8 to 42.9/100,000) https://t.co/XbRYV5Qlwa

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Dutch study of 644 t Early Psoriatic Arthritis pts shows that 17% had no psoriasis (PASI = 0), 71% had mild psoriasis (PASI < 7), 9% moderate psoriasis (7–12) and 4% had severe psoriasis (PASI > 12). PASI didnt fluctuate much in 1st year https://t.co/XW3QhJ65Oz

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#ClinicalPearl Palmar erythema in #SLE #lupus is sometimes painful, may not be fixed and also may have erythema of distal fingers on flexor side https://t.co/C5mysB8pFS
Janet Pope Janetbirdope ( View Tweet)
ICYMI: Metanalysis of Tramadol efficacy & safety in knee or hip #OA. 6 RCTs (3,611 pts) showed little clinical benefit w/ 100/d or 200 mg/d; only 300mg/d was better vs PBO at pain & functional improvement. All doses had higher risk of GI, CNS AEs & W/D https://t.co/wDLHFQWFOe https://t.co/l4B83eUQrW

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