PsA commonly affects peripheral joints. In up to a quarter of PsA patients, the spine may be involved and this is known as psoriatic spondylitis (PsSpA). An important research question is whether PsSpA and Axial Spondyloarthritis (AxSpA) with psoriasis are separate conditions or not.
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Differentiation between a flare of disease and infection in patients with autoinflammatory (AI) conditions, where fever is the hallmark, can be extremely difficult. Few studies have evaluated potential differentiators; and having such tools would meet a huge unmet need.
JointHealth
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Lianne Gensler presenting "Exercise Strategies for Ankylosing Spondylitis". Not all physical activity is similarly beneficial. Learn more now by attending her session at #ACR21!
@CherylKoehn @ArthritisNetwrk @EIM_Canada @exerciseworks @PhysioKTBroker @jwhittak_physio @JasminKMa https://t.co/rER3EdCohO
MRI Imaging in RA and SpA: Dr. Sheila Reyes ( @RHEUMarampa)
Dr. Sheila Reyes discusses abstracts #0468 and #0469, presented at the #ACR21 annual meeting.
https://t.co/MeVia60BNa https://t.co/WRgCifpioQ
CreakyJoints.org
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A study at #ACR21 by Charite-University Medicine Berlin researchers suggests taking tumor necrosis factor inhibitor (TNFi) #biologics earlier in the course of disease could slow down spinal progression in #AxialSpondyloarthritis patients. https://t.co/lDkaMkOcez
sheila
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#Uveitis is the most ⬆ freq xtra-articular manifestation in axSpA.
What factors are assoc'd w/AAU attacks?
👁🗨Active disease
👁🗨History of AAU
Bottomline: Treat axSpA, treat uveitis = better outcomes.
@RheumNow #ACR21 abs1314 https://t.co/O0kHulwJoP
swethaann23
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axSpA and Uveitis
Uveitis
🔼 in HLA-B27; Disease duration; Latin American pts
🔽 in Psoriasis
⭐️Uveitis was not significantly different in axSpA vs pSpA
Recurrent Uveitis
🔼disease duration and body mass index (BMI)
Abst #1307 #ACR21 @Rheumnow https://t.co/QDg8tOPgir
Emerging Therapies in Spondyloarthritis: A Promising Pipeline by Dr. Olga Petryna (@DrPetryna ) #ACR21
https://t.co/9ggUAh0YJe https://t.co/WHpQp3GYBe
Meral K. El Ramahi, MD
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Knowledge Bowl at #ACR21
⭐️Which HLA allele confers an increased risk for anterior uveitis and inflammatory sacroillitis?
➡️HLA-B27
@RheumNow
My summary article on some of the many abstracts at #ACR21 on #WorkParticipation in #axSpA.
Featured abstracts in this article:
#0358 https://t.co/LrZYWqCuOm
#0362 https://t.co/flL5MiqDL8
@RheumNow
https://t.co/tu5L0yIVIV
Richard Conway
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Dr Elliott presenting on US assessment of enthesitis with TNFi vs secukinumab. Surprisingly TNFi showed a more marked decrease in US enthesitis. Abstr#1356 #ACR21 @RheumNow https://t.co/XXgYMgkMyP
sheila
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Waist:Hip ratio may be better than BMI in screening for obesity in #axSpA accdg to this study by @Sineadm15 & colleagues
👉⬆ prevalence of abdominal obesity in axSpA esp among ♀️
@RheumNow #ACR21 abs1322 https://t.co/UB3K7xR9kG
Psoriasis can be diagnosed at any time of axSpA follow up.
Incidence of PsO ⬆️from 16.8% to 26.8% after 6 years
Patients with PsO had more peripheral arthritis and higher BMI
Abs#1311
@RheumNow
https://t.co/IrvHiFqr2m https://t.co/lqCVcF81zA
Peripheral and axSpA pts with low Vitamin D levels (<30) had worse disease activity and functional impairment (BASDAI, ASDAS, BASFI) compared to pts with normal Vit D levels.
Abs#1316
#ACR21 @RheumNow
https://t.co/ulIqOAnWtp https://t.co/aMQaTpduJK
Richard Conway
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@Sineadm15 @bososhea on undiagnosed depression in axSpA. Common, and associated with worse disease activity and quality of life. Abstr#1305 #ACR21 @RheumNow https://t.co/PBH1F3XEGv
We need to be better at identifying and managing #depression in patients with #axspa.
In a group of 70 pts, many had high HADs-D & PHQ-9, with worse disease activity & #QoL compared to those with normal scores.
Abs#1305 #ACR21 @RheumNow
https://t.co/lNoo0HfMcC https://t.co/n7Vyl9L5FR
Females axSpA pts presented w/ higher disease burden (fatigue/tiredness, & spinal pain at night.) Female axSpA pts achieved sign/symptom improvement with IXE later than male axSpA pts. Abs 0934 #ACR21 #RheumNow@RheumNow https://t.co/EGXnfeF6KQ https://t.co/TDF5zxtca7
Pedro Castillo
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@RheumNow From Abst#3053 noted above, here we see the trend of urinary ALCAM with UPCr and renal-SLEDAI https://t.co/3Ujo8WTslO
Pedro Castillo
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AS and PsA: Mortality vs Gen Pop (meta-analysis)
AS:
👉⬆️All-cause
👉⬆️CVD
PsA:
👉All-cause not higher
👉⬆️CVD, Respiratory, and Infectious etiologies
Important to consider CVD and other comorbidities.
https://t.co/9K4qNpYvMb
#ACR21 Abst#0569 @RheumNow
MRI Imaging in RA and SpA: Dr. Sheila Reyes (@RHEUMarampa )
Dr. Sheila Reyes discusses abstracts #0468 and #0469, presented at the #ACR21 annual meeting.
https://t.co/KUoO88dEhQ https://t.co/10R4jC5p0y


