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RheumNow Podcast – Heart, Lung & Liver (5.28.2021)

d Jack Cush, MD

Dr. Jack Cush reviews the news and journal reports from this past week on RheumNow.com.

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Methotrexate Impairs COVID Vax Response

d MedPage Today

One-third of patients with immune-mediated inflammatory diseases being treated with methotrexate showed attenuated responses to the COVID-19 vaccine, researchers reported.

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Efficacy of 6 Weeks Antibiotics with Prosthetic Joint Infections

d Jack Cush, MD

The NEJM has published the results of a French multicenter study showing that prosthetic joint infections can be successfully managed with 6 weeks of antibiotic therapy; this was noninferior and had better outcomes compared to 12 weeks of antibiotic therapy.

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EULAR Guidelines on Intraarticular Therapy

d Jack Cush, MD

EULAR has published evidence-based recommendations on the use of intra-articular therapies (IAT) based on the literature review and recommendations of a multidisciplinary international task force. These IAT recommendations apply to adult patients with peripheral arthropathies.

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Triple DMARD Therapy Bested by Biologics in Swedish Registry

d Jack Cush, MD

The Swedish Register compared outcomes of 1502 rheumatoid arthritis (RA) patients initiating either biologics plus methotrexate (MTX) or triple therapy (MTX plus sulfasalazine plus hydroxychloroquine/chloroquine) and showed similar rates of sustained remission.

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RNL 2021: Treatment Advances in SpA: Dr. Nigil Haroon Dr. Nigil Haroon presents Treatment Advances in SpA at RheumNow Live 2021. https://t.co/9ZA0loThx6

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News: Methotrexate Impairs COVID Vax Response https://t.co/M9d31UAxb7

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New podcast up! Download wherever podcasts are available. https://t.co/y95zS04pqw

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News: Efficacy of 6 Weeks Antibiotics with Prosthetic Joint Infections https://t.co/mSDEIKUL1h

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Danish registry study of 1,356 psoriasis and 370 PsA pts shows increased odd of coronary disease by CT Calcium scores - psoriasis w CACS ≥ 400 OR 1.25 (1.04-1.50); PsA CACS>0 OR 1.28 (1.00-1.64). Nearly a 49% incr risk in PSO (HR 1.49) https://t.co/jQSAV66TAi

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Cross-sectional study RA and PFTs, shows among 2,008 cases, RA was assoc w/ increased odds of restrictive (OR 1.36) & obstructive patterns (OR 1.21) not explained by confounders like smoking. RA had lower predicted FEV1, FVC, FEV1/FVC https://t.co/cVxatLQCG4

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Very cool article in Nature - Tissues, not blood, are where immune cells function https://t.co/NCBSBWhjTX

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Meet the #SLEEducatorsNetwork in this disease education series where leading rheumatologists and nephrologists share their perspectives on lupus nephritis. Sponsored by GSK US Medical Affairs https://t.co/H9BqP9bW4i https://t.co/5AW1IRhBrC

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RNL 2021: Best of times, worst of times (Keynote): Dr. Iain McInnes Dr. Iain McInnes presents his keynote lecture, Best of Times, Worst of Times..., at RheumNow Live 2021. https://t.co/v3hOYuJZad

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We'll be covering EULAR 2021 next week. Look for our coverage from June 3-8. https://t.co/YPNx8MBRn7
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Unable to attend the Tuesday Night Rheumatology on RA and vaccines? Watch the replay below. https://t.co/hUFTjDAnsg https://t.co/ywCRjqg1To

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Virtual DDW meeting this wk reports claims data comparing IBD to IBD with RA - IBD alone vs IBD w/ RA dx w/ more depression (21% vs 84%), anxiety (20% vs 47%). IBD w/ RA had more depression (OR 7.2); anxiety (OR, 1.25;) or both (OR, 2.3) https://t.co/B78xcJw584

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News Feature: CV Risk Decreased with Certain DMARDs in Rheumatoid Arthritis A large prospective cohort study examined the comparative risks of CVD in patients with RA and found that, MTX, ABA & TNFi use were associated w/ a decreased risk of CV events. https://t.co/uQbtB76Hgy https://t.co/ftc5ys9C58

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Mark your calendars--we'll be covering EULAR 2021 from June 3 through June 8. Over coverage will include new articles, videos, polls and more. https://t.co/LksbsK2TW2
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Interesting report of 27 pts w/ Jo-1 anti-synthetase syndrome shows that only 4 had classic triad at presentation. 7 patients presented with polyarthritis, 6/7 initially Dx as #RA, Time gap from RA to antisynthetase dx was 3 to 20 years. https://t.co/IMgk3VTr0c

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