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Fascinating talk by Dr Tombetti on the potential use of arterial wall derived microvesicles collected from plasma as a means of non-invasive liquid biopsy in vasculitis @RheumNow #EULAR2021 Abstr#OP0056 https://t.co/Y6UO2mpjV0
Richard Conway RichardPAConway ( View Tweet)
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After this morning's great discussion at the #epidemiology interest group, Prof Nagy gives a summary of the @eular_org Definition of difficult-to-treat #RheumatoidArthritis at #EULAR2021, including a great summary of the elements and evidence behind the recommendation. https://t.co/imXECTlUbf
EMEUNET EMEUNET ( View Tweet)
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Additional results from @rheum_covid trainee survey re: Telemedicine presented in AB0674:
📱dramatic ⬆️ in telemed (13% to 83%) during pandemic
📱limited training and supervision
📱trainees felt telemed negatively impacted supervision & clin teaching quality
#EULAR2021 https://t.co/44X5UprD7V
Kristen Young kristenyoung ( View Tweet)
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Bariatric surgery decreases the risk of moderate-to-severe hip or knee osteoarthritis.
Burkard. OP0106
#EULAR2021 > FB https://t.co/qh1RQfcvM2
ARD & RMD Open ARD_BMJ ( View Tweet)
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Presented results from @rheum_covid Trainee Survey today at #EULAR21 (POS0051):
👎🏼 trainees felt multiple domains in clinical care & research were negatively impacted by pandemic
🔥 50% felt burntout with 68% with ⬆️ of work related stress
🗣@SuAnnYeoh1, @rheumed & team https://t.co/KXei6r6ZHn
Kristen Young kristenyoung ( View Tweet)
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Following this morning's excellent group discussion on #D2T #RA, Prof Nagy presents @eular_org Definition of #difficulttotreat RA at #EULAR2021
D2T disease, consider:
👉🏼Treatment history
👉🏼Presence of one of the below factors
👉🏼Mx of difficult signs/symptoms as per clinician https://t.co/xbtKuvjLw4
Mrinalini Dey DrMiniDey ( View Tweet)
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Moysidou et al reviewed pubmed registries/longitudinal cohort studies in PsA. 27 registries, totaling 30 countries (67% European, 26% N. American) Africa not represented. This is a call to arms for global PsA pts! #EULAR2021 @RheumNow Poster #POS1078 https://t.co/rsQYR6NFNT https://t.co/MU3FVXuRxS
Links:
Dr. Rachel Tate uptoTate ( View Tweet)
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Dr Lam presenting data on early RA and matched controls. T2T strategy led to no increased CV event risk over 5 years. Longer remission duration protective, higher baseline HAQ associated with higher risk @RheumNow #EULAR2021 Abstr#OP0103 https://t.co/MZdEoyWI64
Richard Conway RichardPAConway ( View Tweet)
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We are truly blessed to live in an era when response to RA treatment is the norm.
(our forefathers looking on jealously from their gold and pencillinamine towers!)
real-world data from BIOBADASER registry OP0123 #EULAR2021 @RheumNow https://t.co/RuQkK1ZXZv
David Liew drdavidliew ( View Tweet)
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tofa/bari in RA H2H vs TNFi comparative efficacy studies highlighted (more head-to-head studies please!) @karolinskainst OP0122 #EULAR2021 @RheumNow (also Swedish national registry data showed tofa/bari comparable to non-TNFi bDMARDs, but no photos allowed!) https://t.co/CUWlK2O94h
David Liew drdavidliew ( View Tweet)
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VTE/VZV in baricitinib & tofacitinib seem unrelated to on-target effects.
Is there VTE/VZV-related off-target culpable binding?
Computer (AI) says no, but...
bari binds PDE10A2 (an antipsychotic target), lab confirmed. Missing link to reduced pain?
POS0091 #EULAR2021 @RheumNow https://t.co/uqYixHhW1z
David Liew drdavidliew ( View Tweet)
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Our SLR on pathogenesis of SARS-CoV-2 Main findings: TH1 cytokines and IL-6 associated w/ severe COVID19 and fatal outcomes. ⬆️ classical blood monocytes and polyfunctional T cells. Impaired IFN response associated w/ poor outcomes. #POS0052 @Rheumnow #EULAR2021 @alessia_alunno https://t.co/PGph5IRBkX
Aurelie Najm AurelieRheumo ( View Tweet)
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Each line is a different country's JAK inhibitor for RA registry, looking at drug stopped for adverse events.
Why all the variation?
(Until we sort that out, we'll struggle to assess JAKi post-marketing safety...)
@k_lauper's JAK-pot study POS0093 #EULAR2021 @RheumNow https://t.co/YykoG7LlEw
David Liew drdavidliew ( View Tweet)
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German SpA Inception Cohort analyses: TNFi assc w/ ⬇️ sacroiliitis and spinal dz progression in axSpA pts, but the effect is evident starting between 2 and 4 years post tx induction. #EULAR2021 Abstracts #OP0137 & #OP0139 @RheumNow https://t.co/uR9rug6zqI https://t.co/xF3wcxm4cf https://t.co/lEsUvOSJ6K
Dr. Rachel Tate uptoTate ( View Tweet)
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RheumNow’s expanded coverage of the #EULAR2021 Annual meeting is sponsored in part by Novartis, Bristol Myers Squibb, Janssen. All content chosen by RheumNow & its Faculty.
Dr. John Cush RheumNow ( View Tweet)
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@jeffsparks wahooo! Congrats on the #EULAR2021 clinical science award recognition!
Dr. Rachel Tate uptoTate ( View Tweet)
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#EULAR2021 #EULAR21 #eular #spondyloarthritis
I have always thought we named nr-axSPA wrongly - Tends to trivialise its gravity and importance
Shouldn’t it be our goal to diagnose all SpA at the nr-axSPA stage
@deodhara @NigilHaroon https://t.co/zwKI1o9WcO
EnvisionRheumat ERheumat ( View Tweet)
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Patient profiles have changed in clinical trials of PsA #EULAR2021 https://t.co/6l2RfOPkSq
Dr Irwin Lim _connectedcare ( View Tweet)
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#EULAR2021: AxSpA patients with greater patient-reported pain and spinal pain relative to axPsA patients among real-world patients in CorEVitas' Psa/Spa observational Registry per Dr. Mease's oral abstract presentation. @RheumNow https://t.co/YEdhd7x6cb
Meral K. El Ramahi, MD MeralElRamahiMD ( View Tweet)
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#EULAR2021 - Key points from Dr. Mease's oral abstract:
⭐️AxSpA pts were younger & more likely to be male & have a hx of uveitis & IBD
⭐️AxSpA pts had less exposure to prior therapies relative to axPsA pts
⭐️AxSpA assoc w/ > spinal pain regardless of b/tsDMARD status
@Rheumnow
Meral K. El Ramahi, MD MeralElRamahiMD ( View Tweet)