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OP0010 at #EULAR2021. FLORA trial: Fecal microbiota transplant as add-on Rx to MTX. Small trial showing time-to-event curves show inferiority to sham but good safety. Fascinating concept exploring gut-joint interaction. @RheumNow. https://t.co/BIOmA5z6vK
Eric Dein ejdein1 ( View Tweet)

Some interesting abstracts at #EULAR2021 today on monitoring GCA with:
- ultrasound
OP0055 https://t.co/0fqLIK5IPV
- PET/CT
OP0069 https://t.co/WQl9VaHR9E
OP0064 https://t.co/w7biFT6qy0
What do you believe is the most accurate measure of true disease activity in GCA? @RheumNow
Links:
David Liew drdavidliew ( View Tweet)

Dr Arnold @Yuz6Yusof present on personalised rituximab retreatment in AAV. Interesting that naive B-cell repopulation at 6 months predicts better sustained response compared to absence @RheumNow #EULAR2021 Abstr#OP0057 https://t.co/cypyQVMeYz
Richard Conway RichardPAConway ( View Tweet)

IVIG pending FDA review for tx of dermatomyositis after ProDERM study. Do you use IVIG for tx of DM?
#EULAR2021 @RheumNow
Robert B Chao, MD doctorRBC ( View Tweet)

ProDERM RCT IVIG in Dermatomyositis
⭐️improved TIS scores compared to pbo
⭐️common AE: headaches, pyrexia, nausea
⭐️serious AE: PE, CVA, DVT
⭐️approved in Europe, pending FDA
Abs#OP0008
#EULAR2021 @RheumNow
Robert B Chao, MD doctorRBC ( View Tweet)

Comparison of disease activity and PROs in AxSpA vs. AxPsA
⭐️AxSpA ⬆️ uveitis and IBD
⭐️AxPsA ⬆️enthesitis and dactylitis
⭐️AxSpA pts ⬆️pain, spinal pain PROs
⭐️Fatigue and work impairment did not differ in AxSpA vs AxPsA
Abs#OP0049 #EULAR2021 @RheumNow https://t.co/wGD6IA5ahb
Robert B Chao, MD doctorRBC ( View Tweet)

@jeffsparks knocking it out of the park presenting our findings on b/tsDMARD associations with COVID-19 outcomes @eular_org @EULAR_Press check out our full paper just published in @ARD_BMJ https://t.co/jcA1LN45R3
Zach Wallace zach_wallace_md ( View Tweet)

Dr Palomäki on influence of MUC5B promotor variant on ILD risk in RA and non-RA. Lifetime risk ILD 14.5% for RA+MUC5B+, 5.2% for RA+MUC5B-, 3.9% RA-MUC5B+ 1.3% RA-MUC5B- @RheumNow #EULAR2021 Abstr#OP0007 https://t.co/BnexQE1Pw9
Richard Conway RichardPAConway ( View Tweet)

Dr Ponte presenting on use of halo sign on TA US to monitor GCA disease activity. Seems good, present and increased in 16/17 (94.1%) cases of first disease relapse @RheumNow #EULAR2021 #AbstrOP0055 https://t.co/T6hKjkb4AT
Richard Conway RichardPAConway ( View Tweet)

Abs#OP0009 presents 8 min web-based video for COVID vax education sent via text message. 76% more likely to get vax. #EULAR2021. @RheumNow. Pts need to hear from their rheumatologists our thoughts on vax, ideally in person, but phone is great outreach https://t.co/aimGBufYpe
Eric Dein ejdein1 ( View Tweet)

Excellent job by @jeffsparks @zach_wallace_md @rheum_covid on Abs#0P0006 at #EULAR2021.
⭐️RTX and JAKi: increased COVID severity, not seen in IL-6 or ABA. Critical findings, but confounding role of co-morbidities/ILD/cancer, esp in RTX patients? @RheumNow
Eric Dein ejdein1 ( View Tweet)

Dr. Tani: Who has trouble tapering below 5mg/d prednisone in SLE
☑️Older patients
☑️High disease activity
☑️Skin and MSK manifestations
☑️Pts treated before 2000.
Try to avoid long-term steroid usage early in the disease course, as it gets harder over time. #EULAR2021, @RheumNow
Eric Dein ejdein1 ( View Tweet)

Excellent talk by @LCalabreseDO on the balance of the immune response!
⭐️Exhausted T cells seen in rheumatic dz, chronic infections, cancers, severe COVID-19
⭐️CPI for treatment of latent infections? CPI for treatment of COVID? 🤔
Abs#OP7137 #EULAR2021 @RheumNow https://t.co/18rvFkpPTx
Robert B Chao, MD doctorRBC ( View Tweet)

Secukinumab effective in AS patients, irrespective of gender
AQUILA 52 week study
⭐️improvement in BASDAI, PGA, severity of depressive mood in both men and women
⭐️women had overall higher disease burden in global functioning and depressive mood
POS0899
#EULAR2021 @RheumNow
Robert B Chao, MD doctorRBC ( View Tweet)

Dr Atienza-Mateo presents abstract #POS0595 on abatacept in RA-ILD. Abatacept surprisingly appeared to be equally good in stabilising FVC and DLCO in both UIP and NSIP patterns in RA-ILD. @RheumNow #EULAR2021 Abstr#POS0595 https://t.co/kHUxWXnaBG
Richard Conway RichardPAConway ( View Tweet)

I'm presenting data on COVID-19 in Irish rheumatic disease patients. Age, number comorbidities, glucocorticoids, associated increased hospitalisation. Inflammatory arthritis associated decreased hospitalisation. @RheumNow #EULAR2021 #AbstrPOS1162 https://t.co/0gKxiMNYTf
Richard Conway RichardPAConway ( View Tweet)

#EULAR2021 recommendations: RMDs face no more risk of contracting COVID-19, no current evidence of worse prognosis. Do you tell patients similar stats? @RheumNow
Eric Dein ejdein1 ( View Tweet)

#EULAR2021 recommendations on mgmt of RMD in COVID: continue treatment if symptom free, steroids at lowest dose. @Rheumnow. https://t.co/U5zr7EHvTv
Eric Dein ejdein1 ( View Tweet)

Seeing the sites of Paris at virtual #eular2021. Follow on @RheumNow along with @RichardPAConway @MeralElRamahiMD @Yuz6Yusof @Stiddyo @KDAO2011 @uptoTate @AurelieRheumo @drdavidliew @Janetbirdope https://t.co/w18REG08nz
Eric Dein ejdein1 ( View Tweet)

@RheumNow I will be tweeting alongside an amazing team @RichardPAConway @MeralElRamahiMD @Stiddyo @KDAO2011 @uptoTate @Yuz6Yusof
@drdavidliew @ejdein1 @Janetbirdope @TammyTilley & last but not least Dr Cush! Follow them and @Rheumnow to stay tuned for the latest science! #EULAR2021
Aurelie Najm AurelieRheumo ( View Tweet)