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RheumNow Podcast- Corona Increases RA Risk (3.13.20)

d Jack Cush, MD

Dr. Jack Cush reviews the news and journal articles from the past week on RheumNow.com.

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Earlier Anakinra Initiation Warranted in Still's Disease

d Jack Cush, MD

An Italian study examined the outcomes in adult onset Still's disease (AOSD) based on whether they received early or delayed treatment with anakinra (ANK). 



A total of 141 AOSD patients were retrospectively studied.

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Switching Biologics in JIA

d Jack Cush, MD

While there are numerous agents approved for use in juvenile idiopathic arthritis, little is know about actual use biological disease-modifying antirheumatic drug (DMARD) use or switching in the biologic era. A cohort comparison study has shown that after an unsuccessful trial of a first biologic, changing to a second TNFi is as effective as switching to a non-TNFi biologic.

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The HOP-STEP contraceptive handout for SLE. 1st determine the risk of blood clots. Dr. Megan Clowse #RNL2020 https://t.co/PPdSve4PUH
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Dr. Megan Clowse #RNL2020 never tell a woman she cannot get pregnant. It's the same as saying you can never be another. Choose your words wisely. https://t.co/gtPA0NiJmx
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Pregnancy outcomes in SLE. Adverse outcomes are increased. Dr Megan Clowse #RNL2020 https://t.co/NaOAw5tDHA
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Nurse lead care of gout is superior to usual care. Dr Nicola Dalbeth #RNL2020 https://t.co/hR47KdyrtH
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Patient perceptions difference when you call it gout of urate Crystal arthritis. Gout an inflammatory dietary state vs UCA being are related. Dr Nicola Dalbeth #RNL2020 https://t.co/1IzARIYltO
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Yet society mostly focuses on dietary manager of gout. Dr Nicola Dalbeth #RNL2020 https://t.co/qcpoBZ42BK
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Dr Nicola Dalbeth #RNL2020 notes there are no RCTs regarding dietary manager of #gout

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Dr Jose Scher #RNL2020 comorbidities and psoriatic dz. Studies inconsistently show that control of psoriasis lowers C V risk https://t.co/qTd8tt7qLt
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A study of 656 symptomatic Knee OA, the presence of knee chondrocalcinosis did not affect the risk of future arthroplasty or disease progression at 5 years. https://t.co/biXikX0YKw

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Tawain insurance claims study of 521 SLE pts shows SLE to have increased frequency of ophthalmologic problems (P <  0.001) - dry eye (IRR 4.45), cataracts (IRR 3.18), glaucoma (2.23), episcleritis and scleritis (6.11), retinal vascular occlusion (3.81) https://t.co/t0cScblggd

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QD Clinic - Managing Comorbidities in Psoriatic Patients; whats the rheumatologists role? Watch it here>> https://t.co/vM1FxEceKu or listen to the podcast on iTunes or Soundcloud >> https://t.co/OEVuLUItZ9

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QD Clinic - Chat 'em Up. The need for chit chat in the clinic. Watch it here>> https://t.co/vM1FxEceKu or listen to the podcast on iTunes or Soundcloud >> https://t.co/OEVuLUItZ9

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TNF inhibitors may slow, but do not stop, Xray progression in AS, Anti–IL-17A agents may maybe the same. Study by Inman et al shows that Tyk2 inhibition may prevent xray damage (animal model) by blocking IL-23 signaling and IL-22 production. https://t.co/OyyKoqdCl9

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Dr Alan Menter #UTSW Rheum Grand Rounds the cause of death in psoriasis is mostly cardiovascular https://t.co/PPQqO4rS5h
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CORRONA study of 24,528 #RA pts; 32% also has Sjogrens syndrome (overall SS prevalence in RA = 0.30 ). SS more likely with increasing RA duration, older, female, seropositive; higher DZ activity; more comorbidities and extra-articular manifestations https://t.co/EgTSzKHmtL

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193 #RA pts starting a TNFi followed for 12ms; 21.7% were non‐adherent to TNFi - No difference between different TNFi's. Predictors of nonadherence included High age, low DZ activity, ^^comorbidities, more injection site pain & Rxns https://t.co/qclzJiglMj

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QD Clinic is up - this one is all thing leflunomide - Aravarama! Watch here>> https://t.co/UTHIA8mDPH or Listen to the podcast on iTunes or here>> https://t.co/bK2kmKfDOQ

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