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Dr. L Calabrese excellent review of irAEs and a proposed personalized algorithm for mgmt of irAE #ACR20 @LCalabreseDO @rheumnow
He believes there should be more studies combining TNFi or IL-6 with CPI https://t.co/GbvgXtNJnI
k dao KDAO2011 ( View Tweet)
Looking forward to learning lots in the next 20mins on how to approach #telemedicine to provide better care for our patients.
Important to remember to keep patients at the centre of our priorities.
#rheumtwitter
Session 2F05 #ACR20 @RheumNow https://t.co/aBrnytCWpu
Mrinalini Dey DrMiniDey ( View Tweet)
Behind the scenes at our #irae “study group” @NohaMDAnderson @LCalabreseDO #ACR20 #Immunotherapy https://t.co/eE7E7Qi1Zq
Cassandra Calabrese CCalabreseDO ( View Tweet)
Dr. Noha Abdel-wahab on timing for grade 3/4 irAE fastest with the skin after exposure to CPI #ACR20 @rheumnow https://t.co/sc5c6Zn3Uq
k dao KDAO2011 ( View Tweet)
#hydroxychloroquine is not a ‘cutie’ drug. E Park et al showed that HCQ does not increase QT interval in RA & SLE patients including if on other meds that may affect QT but known heart disease excluded from study #ACR20 #ACR2020 @RheumNow abstr#432 @CRASCRRheum https://t.co/FGVPknmj5q
Janet Pope Janetbirdope ( View Tweet)
#ACR20 Break time - go take a hike OR go ride a bike!
https://t.co/rYW3p4OgE3
Links:
Dr. John Cush RheumNow ( View Tweet)
@Rhemnow #ACR20 abs0307 analysis of PsA pts diagnostic pathway emphasizes difference in Dx coding by specialty (Derm unlikely to code arthritis, rheum unlikely to code PSO, PCP tend to code general MSK and axial symptoms). PSO and enthesitis codes increased closer to PsA Dx https://t.co/i6ZmjlD3xs
Olga Petryna DrPetryna ( View Tweet)
ACHILLES study: Only 56% of pts w/ clinical enthesitis had MRI+ heel enthesitis. MRI screening: HLAB27+ pts likely to be in MRI+ grp. @RheumNow #ACR20 Abstr#0447 #ACRbest https://t.co/m2cjDzYfyg
sheila RHEUMarampa ( View Tweet)
More UPA safety studies Abst#0215 shows balanced VTE event rates across UPA doses and comparator groups. Evidence for Dr. Strand to use in #ACR20 Great Debate that VTE may be safe TNF alternative @RheumNow. https://t.co/hByttIxiuX
Eric Dein ejdein1 ( View Tweet)
“Immunology is the cornerstone of medicine and we are the experts.” #ACR20 president, Dr. Ellen Gravallese @RheumNow
Dr. Rachel Tate uptoTate ( View Tweet)
Sustained DMARD-free remission (SFDR) seen in ACPA- RA pts; DAS levels at 4mos. predictive for SFDR. ACPA+ pts no relation w/ SFDR & DAS course @RheumNow #ACR20 Abstr#479 #ACRbest https://t.co/kko4tO7s1Y
sheila RHEUMarampa ( View Tweet)
Small study showed poor to fair agreement of PE and US findings of hands in PsA. Do you use US in your clinic for diagnostics? #ABS0314 @RheumNow #ACR20 https://t.co/6oQG4SB1d3 https://t.co/SQK7uhX02T
Dr. Rachel Tate uptoTate ( View Tweet)
JAKs are no longer new, Winthrop et al presents 8.4 year BARI data in Abst#0202 at #ACR20. VTE risk stable over time, again shows reason to vaccinate patients for zoster before starting. @RheumNow https://t.co/OSIvHl2f7Y
Eric Dein ejdein1 ( View Tweet)
Beautiful poster and fascinating research from @chriswincup et al showing immune cellular iron deficiency in patients with #SLE. Time to add iron supplementation as part of standard #lupus therapy?
https://t.co/Uf81KXbSM0
Abs#0294 #ACR20 @RheumNow https://t.co/z5SUjWFkdD
Mrinalini Dey DrMiniDey ( View Tweet)
Abst#0181 out of Korea shows MTX use does not increase prevalence of hepatic steatosis. Encouraging data, though retrospective study may underpin provider bias in riskier patients. #ACR20 @RheumNow. https://t.co/HeR5hroYUh
Eric Dein ejdein1 ( View Tweet)
ANA antibodies in longitudinal #SLE cohort:
- 759 patients
- 84.8% remained ANA+ve during 5yr followup period
- Pts w/ at least one -ve ANA in first 5yrs had milder disease (lower SLEDAI-2K, less steroid, fewer autoantibodies)
Abs#0251 #ACR20 @RheumNow
https://t.co/U7JbNpJA3w
Mrinalini Dey DrMiniDey ( View Tweet)
Large data from Japanese Ninja database in abst#0183 shows incidence of malignancies in Japanese RA patients similar to Japanese gen pop. Comparable in patients exposed and unexposed to biologics/JAKs. #ACR20 @RheumNow
Eric Dein ejdein1 ( View Tweet)
15 % of Relapsing Polychondritis meet diagnosis for MAGIC syndrome (Mouth and genital ulcers with inflamed cartilage) - overlap of RP and Behcet's Abst#0425 #ACR20 #ACRbest @RheumNow https://t.co/qaHWwOOL7Q
Bella Mehta bella_mehta ( View Tweet)
Great debate by Dr. Weinblatt and Dr. Strand on JAKinibs vs TNFi in RA! How long do you tx with JAKinibs before calling it a failure? @RheumNow #ACR20 #ACRbest
Robert B Chao, MD doctorRBC ( View Tweet)
PMR takes fit patients, and drags them down.
In this @HSpecialSurgery cohort, PMR patients were more frail: worse physical function, fatigue, and pain - despite a low comorbidity burden.
We need to understand the burden of PMR better. IL-6?
@SattuiSEMD #ACR20 ABST0422 @RheumNow https://t.co/j6HLNA7ANv
David Liew drdavidliew ( View Tweet)
