Inverse association between average yearly HCQ dose and CV damage in cohort of SLE pts from Abs 0982 #ACR22 @RheumNow https://t.co/sfB6ONgwOa https://t.co/FAUGAVe2mB

• Effect of Cumulative Hydroxychloroquine Dose on Prevention of Damage Progressio…

Curtis et al @RADoctor . IL6i more effective than conventional immunomodulators in refractory PMR. More likely to discontinue GC (HR 1.32), minimal GC (<2mg) (HR 1.30). @RheumNow #ACR22 Abstr#1547 https://t.co/uzSzrLQ9cB https://t.co/G4pEkOgYm2

• Effectiveness of Interleukin-6 Receptor Inhibitors for Polymyalgia Rheumatica -…

Alle et al. ITP develops into SLE 5.6/1000py. 5.4% of ITP in this study developed SLE after 1801.4py follow up. Assoc refractory ITP, low complement, cytopenias, LA, hypergamma, high titre ANA. @RheumNow #ACR22 Abstr#1455 https://t.co/ORTeB0Q9Pi https://t.co/AVo97uMbpW

• Immune Thrombocytopenic Purpura and Subsequent Development of Systemic Lupus Er…

Nice RS3PE irAE description from CanRIO Two of my RS3PE irAE pts: both severe Sx one in 2018: not enough PNL until palliation & suffered until then one in 2022: prompt diagnosis, right PNL dose, living v well now Hopefully we always continue to improve ASBT0758 #ACR22 @RheumNow https://t.co/5Ps2HRllNC

A diagnostic delay of 6 months of #psoriaticarthritis was assoc w/ ⬆️incidence of depression ⬆️limitation in participation of social roles & activities ⬆️impact on QoL in this study by George Gondo @NPF & team 🔖Take home msg: Early dx of PsA is key! #ACR22 @RheumNow ABST1507 https://t.co/wIZT4MKV4b

TMP-SMX PPX dispensed to less than a quarter of GPA pts at the time of RTX. Recent GC had the greatest association w/ PPX. Do you prescribe PPX for your GPA pts #Rheumtwitter? Abs 1071 #ACR22 @RheumNow https://t.co/qJyuGATtJo https://t.co/w4UaGgjEW1

• Trimethoprim Sulfamethoxazole Use in Patients with Granulomatosis with Polyangi…

Shall we cycle TNFi in AxSpA? CorEvitas registry 86 pts 70% TNFi monotherapy, 23% NSAIDs, 42% high & 24% v high DA Cycling to 2nd line TNFi At 6 months: very low achievement of ASDAS-LDA (15%), MCID in ASDAS (7%) & no MI. https://t.co/S9vnz5PXuX Abs#1499 #ACR22 @Rheumnow https://t.co/1IZIYcPCBz

• The Impact of Cycling Among Tumor Necrosis Factor Inhibitors on Disease Control…

Pan et al 11beta-hydroxysteroid dehydrogenase inhibitor SPI-62 mitigates glucocorticoid toxicity in mouse model. Human trial in PMR ongoing. @RheumNow #ACR22 Abstr#1549 https://t.co/t74Hazll9H https://t.co/4425RUwIz4

• Toward Safer Glucocorticoid Therapy - ACR Meeting Abstracts

Mepolizumab assoc'd w/ clinical benefits in EGPA, including in patients w/ and w/o a vasculitic phenotype. Abs 1074 #ACR22 @RheumNow https://t.co/VCGhGaci8b https://t.co/OV8A1vsx1G

• Efficacy of Mepolizumab in Patients with Eosinophilic Granulomatosis with Polya…

Filho et al. Retrospective Brazilian study. ADA vs LEF in Takayasu arteritis. Comparable renission, relapses, steroid dose, ESR, CRP, imaging over median 15 weeks. More AEs in LEF but non-severe. @RheumNow #ACR22 Abstr#1553 https://t.co/499dUNmpUD https://t.co/AEk5cG7dc4

• Effectiveness and Safety of Adalimumab versus Leflunomide in Patients with Taka…

Juge @Juge_P_A @PhilippeDieude et al. RA-ILD patients have shorter telomere length than RA without ILD. RA-ILD similar telomere length to IPF. OR 0.54 for RA-ILD. Assoc with FVC%pred also. @RheumNow #ACR22 Abstr#1122 https://t.co/H5A7unpjjB https://t.co/IjvHmupykM

• Short Peripheral Blood Leukocyte Telomere Length in Rheumatoid Arthritis - Inte…

Del-Río-Guerrero et al. Sphygmomanometry-induced allodynia for fibromyalgia detection. 62% sensitivity and 84% specificity. Much pain = 23% sensitivity and 96% specificity. Only seems to apply in female patients. @RheumNow #ACR22 Abstr#1225 https://t.co/zCHfmvwOcn https://t.co/tjBBny0WSR

• Sphygmomanometry for Fibromyalgia Detection in a Rheumatology Outpatient Clinic…

Abstr 1255 Do Rheumatologists overcall sacroiliitis on imaging in axSpA? Compared to central readers: -Agreement w/ local readers = 87% agreement (X-Rays); 74.5% (MRIs) - Agreement w/ Academic rheumatologists was greater vs community rheumatologists #ACR22 @RheumNow https://t.co/j2vFoKA3n0

Study by Dr EPapachristodoulou on features of #lupus pts w/ LAD: myo/pericarditis, cytopenias, nephritis,⬆️markers Those w/LN biopsy: reactive(66.7%) vs. necrotizing(33.3%) pattern 👉Pts w/ necrotizing pattern: unexplained fevers, sicca& malar rash. #ACR22 @RheumNow ABST1443 https://t.co/J4aMRnYk8N

Avacopan's efficacy and safety profiles support use in AAV in Abs 1077 #ACR22 @RheumNow https://t.co/Zp05ofTgFP https://t.co/zA2sIEfYCS

• Safety of Avacopan in ANCA-Associated Vasculitis: Combined Data from Three Clin…