Kicking things off with South Philly Barbacoa! #ACR22 #ACRTacoFest #ACRTacoTrot #RheumPix @AliDuarteMD @rheumecraig @BharatKumarMD @maio_danila @SattuiSEMD @RheumNow https://t.co/cxoCuYesDZ

Look at these graphs and try and tell me that sex and gender doesn't matter in RA. We have seen in study after study after study - sex and gender matters. ABST0241 @erasmusmcintl #ACR22 @RheumNow https://t.co/GQnKrAp0eB https://t.co/MxHRy2kwDN

• https://twitter.com/TheLancetRheum/status/1572873396123504641

What's the difference between RA and PsA on hand MRI? Removing our cognitive biases, here's what a neural network has to say (not hard to see the power of this work) ABST0242 @LkasDer @maier_ak #ACR22 @DrCMcMaster @RheumNow https://t.co/TqS6xUZNtl

Abst0327 #ACR22 SMART-SLE Monitoring Some SLE patients with +dsDNA have persistent positivity, others have fluctuations Anti-dsDNA in persistently positive HR 1.56 for flare risk Change (up or down!) in dsDNA more than 2x prior visit for fluctuating patients: HR 1.43 @RheumNow https://t.co/YwDPTYWPLu

It's always amazed me adalimumab & abatacept, have very different MOA but similar efficacy in RA - on a population level. Not for individuals, though. Surely we can pick the winners better? Lovely biomarker work from a H2H RCT ABST0244 #ACR22 @RheumNow https://t.co/qVttIZSQtc

Abst0324 #ACR22 How close are we to measuring Interferon Signature in clinical practice? NCounter and BioFire assays studied - correlated well we each other Genes: IFI27, IFI44L, IFIT1, RSAD2 SLE higher than RA or FMS, but does not correlate with SLE activity @RheumNow https://t.co/izpFtj9Pcd

Abst0326 #ACR22 Anti-Mitochondrial Ab in SLE Whole mitochondrial (AwMA), AmtDNA or AmtRNA - higher in SLE compared to controls AwMA predictive of death, AmtDNA and AmtRNA predictive of nephritis @Rheumnow https://t.co/d98HSHnJVE

What if my patient with RA or PsA gets pregnant? @RheumNow #ACR22 Abstract #1786; 34 women 👶 Disease scores improved during #pregnancy and increased #postpartum 👶20-27% of women required a cesarean delivery 👶mean delivery 39-40 weeks gestation 👶 1 NICU admission https://t.co/qYPaB6TcDJ

JAK inhibitors in RA: does their performance vary in the real world? @opal_ltd 🇦🇺: n= 5900 JAKi-treated RA pts, 2015-2021 upa is relatively new in Australia, but amazing how bari and tofa are so similar (same with the data on switching reason too) ABST0274 #ACR22 @RheumNow https://t.co/63PrRVAzk5

Abst0328 #ACR22. Predicting UCTD to CTD Meta-Analysis Factors for SLE transition: younger age, serositis, dsDNA SSc transition: puffy finger, NFC, or SSc antibodies No studies wo moderate or high risk of bias Limited studies on biomarkers for SLE, need more studies @Rheumnow https://t.co/GofGF8TkCx

Time check!⌚🦉 This roaming clockface helps me navigate through time zones while attending #ACR22 ✈️virtually jetlagged but having fun!🤓 @RheumNow @rheumarhyme @doktora_ging #RheumPix https://t.co/HgTcIyw7ej

Infections in JAKi v TNFi in RA We've seen ORAL Surveillance data What about East Asian pts, with enriched zoster risk? National KOR🇰🇷 insurance data: Bacterial: equal Opportunistic: TNFi worse Zoster: JAKi worse serious zoster a lot more common here! ABST0302 #ACR22 @RheumNow https://t.co/lxsbY1Nf9N

“Conflict, crisis and resolution make a story. A good story has drama where there is desire with danger.” @cuttingforstone author, Dr. Verghese noted the COVID19 #pandemic has all of these elements. It is a good story, but we don’t know the resolution. @Rheumnow #ACR22 https://t.co/Tomev2SYcT

RheumNow’s expanded coverage of the #ACR22 Annual meeting is sponsored in part by Novartis. All content chosen by RheumNow & its Faculty.