Mike Putman EBRheum
3 years 11 months ago
Pooled data from belimumab RCTs w/>3,000 pts evaluating kidney outcomes vs PLBO
Tagging off BLISS-LN, pooled analysis w/marginal but real benefit to adding BEL in pts with SLE
I offer this to all pts w/SLE LN on MMF, but I do not push it
#ACRbest #ACR22 @RheumNow #0352 https://t.co/QYGgB3ue36
TheDaoIndex KDAO2011
3 years 11 months ago
Consensus for #cancer screening in IIM Presented: When to Go Beyond Standard and Extended Screening #Plenary #ACR22 @rheumnow #myositis #ExpertOpinionNotData https://t.co/cL6zrMnzT3
David Liew drdavidliew
3 years 11 months ago
Cancer screening in myositis:
the path has always been unclear and inconsistent
Workable consensus recommendations @Dr_Alex_Oldroyd
risk stratification but still extensive investigation burden for most
now need to look at effectiveness including cost
ABST0002 #ACR22 @RheumNow https://t.co/322qnGjB9K
Md Yuzaiful Md Yusof Yuz6Yusof
3 years 11 months ago
#ACR22 Abstr#0002 @Dr_Alex_Oldroyd presented eminence-based recommendation for patients with inflammatory myopathy. Enhanced screening for those high risk. Studies needed to assess feasibility i.e. cost, positive and negative predictive value of test etc. @RheumNow https://t.co/G1MyQDMhOa
TheDaoIndex KDAO2011
3 years 11 months ago
Consensus for #cancer screening in IIM Presented: How Often to Screen #Plenary #ACR22 @rheumnow #myositis https://t.co/h1kp7Z9ynO
TheDaoIndex KDAO2011
3 years 11 months ago
Consensus for #cancer screening in IIM Presented: What tests to order for screening #Plenary #ACR22
@rheumnow #myositis https://t.co/pPLcsFLtG9
TheDaoIndex KDAO2011
3 years 11 months ago
Consensus for CA screening in IIM Presented: Risk factors to consider screening
#Plenary #ACR22 @rheumnow #myositis https://t.co/CDNPaRUpPS
Julian Segan JulianSegan
3 years 11 months ago
Risk stratification for cancer in myositis
@RheumNow #ACR22 #Plenary https://t.co/j7R7P3PS7c
Julian Segan JulianSegan
3 years 11 months ago
Some suggested screening tests for malignancy in myositis. Recommendations based on assessment of risk factors
@RheumNow #ACR22 #Plenary https://t.co/B0eASeo8hG
Mike Putman EBRheum
3 years 11 months ago
Nice #SLE validation study. This kind of work is (1) time intensive and (2) thankless!
It's not flashy but it winds up being the backbone/foundation for many subsequent studies
Need more in other diseases, including sarcoidosis and myositis! @DidemSayginMD
#ACR22 @RheumNow https://t.co/64z7DBFCnX
David Liew drdavidliew
3 years 11 months ago
GUSTO 1y follow-up (TCZ +IVMPx3 but no ongoing PNL in new GCA):
initial 24w results disappointing (permanent visual loss x1)
BUT follow-up at 2y: control overwhelmingly maintained in responders
We need to keep asking: can we use less PNL in GCA? When?
ABST0470 #ACR22 @RheumNow https://t.co/smyw2nykO5 https://t.co/d2at0pJlSB
Catherine Sims, MD DrCassySims
3 years 11 months ago
Xeljanz in PsA (@pfizer funded) #ACR22 @RheumNow
⚠️safety data
-Pancytopenia
-Transaminitis
-Dyslipidemia
-Elevated CPK without #myositis
-Avoid in pregnancy and GI strictures
🤰Stop JAKi at least one month prior to conception🤰
Md Yuzaiful Md Yusof Yuz6Yusof
3 years 11 months ago
#ACR22 Plenary 1. Abstr#0001 Another important use of #methotrexate. MIRROR RCT showed greater response in pegloticase + MTX vs pegloticase + PBO and lower infusion reaction. Be interesting to define MTX dose and ?other DMARDs esp in patients with CKD @RheumNow #ACRBest https://t.co/xkP6ZZGQfu
Bella Mehta bella_mehta
3 years 11 months ago
Abst#0001 MIRROR RCT at #ACR22 #plenary
Pts with gout on #pegloticase and #gout
sustained higher urate lowering response in pts cotreated with #MTX
benefit beyond 6 months
@rheumnow https://t.co/rTZ3fPaFJS
Catherine Sims, MD DrCassySims
3 years 11 months ago
Xeljanz use in AS #ACR22 (@pfizer sponsored) @RheumNow
-Included patients with at least bilateral grade 2 SI or grade 3/4 unilateral SI
-5mg BID Xeljanz
-Significantly more patients had ASAS20/40 response, CRP reduction, & QOL, vs. placebo
-Onset of action noticed at 2 weeks https://t.co/DisKpgR0pt

