Pre and post-COVID-19 assessment of 78 FM pts by Fibromyalgia Impact Questionnaire-Revised (FIQR). While COVID affected FM pts, there was no statistically significant change in FIQR scores (65% had no improvement or deterioration on FIQR) https://t.co/S1clBCvzWm https://t.co/ZApmgvKM2c

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2022 ASAS-EULAR Guidelines for Axial Spondyloarthritis Assessment of SpondyloArthritis international Society (ASAS) and EULAR have published their 2022 update and recommendations for the management of axial spondyloarthritis (axSpA). https://t.co/oX8oXm0adU https://t.co/JyzT6VxMSQ

• https://bit.ly/3snQrP9

TNF inhibitors Dont Increase Cancer Risk! 4592 RA pts:TNFi Rx (2296) vs matched DMARD Rx (2296) pts. TNFi had a lower cancer risk than DMARD Rx (IR 6.5 vs. 15.6 /1000PYs]). TNFi had Lower HR GI CA (0.432), breast CA (0.146), GU CA (0.220) https://t.co/F5ToHLJULn

Mayo Clinic Biobank matched case-control study (1:3) of 212 incident RA cases Active work physical activity lowered risk of RA (aOR 3.00), while 3-5 servings high-fat foods, fruits/vegetables lowered risk (OR 0.45; OR 0.54). https://t.co/AAQ1nRfJXq https://t.co/72yLQUllDV

• https://bit.ly/3F90bEi

1915 Rheumatic (RMD)pts w/ COVID (42% RA. 15% SLE, 1/2 comorbidities); Outcomes: 28% hospitalized, 8% to ICU & 4% died from COVID-19. Poor COVID-19 outcomes seen w/ age, male, Hi Dz activity, steroids & RTX, & 1+ comorbidity https://t.co/ztBiJc9nxV https://t.co/RVOKyjseFJ

• https://bit.ly/3DuBFMB

Acute Hot Joint? A systematic review of 49 articles, looking at SF & serum markers to distinguish septic vs non-septic joints. They found 8 discriminatory SF tests w/ WBC esterase highest sensitivity (0.94)& specificity (0.74) https://t.co/SamgBwyBrL https://t.co/t9JOiRMMHI

• https://bit.ly/3MWPc2S

#Gout clinic study of 223 gout pts on allopurinol ≥300 mg compared Pt & MD gout control assessments (0-10). Better agreement & higher scores seen w/o flares (3 or 12 mos) & SUA w/in target. Disagreement (22%) w/ recent flares & tophi https://t.co/a0WsMLvfYk https://t.co/zZwV4XVJzS

• https://bit.ly/3Dq7K8m

Metanalysis of emergency department Rx of opioids for MSK pain - 42 articles, 6128 pts - Short term (2hr) benefits of ED opioids were statistically but not clinically more effective than PBO or Tylenol, but not better than NSAIDs. Safety uncertain. https://t.co/Lmf8Ubuacw https://t.co/prP6Ei3wqA

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Will we see you there? #ACR2022 What are you most looking forward to on the agenda? https://t.co/6nUMBmqnTy

Predictors of serious infection (SIE) in SLE? A prior SIE conferred the highest risk of subsequent SIE. Study of 346 SLE pts shows SIE rate of 3.8/100 Pt-Yrs. Other risk factors: Damage accrual, comorbidity, Dz activity, CTX use https://t.co/t65XzmFzQG https://t.co/78jiUnaq7d

• https://bit.ly/3SH4mdW

Love the RheumNow podcast? Subscribe, rate and review! Listen in the car, airplane, anywhere! We also reach more listeners through reviews from our users. Consider leaving a review! https://t.co/QlcUIxqY8A https://t.co/k2ybeeYGz5

• https://bit.ly/3D2e4BI

Pregnancy Outcomes with Belimumab A study of SLE pregnancies exposed to belimumab (BEL) shows and expected rate of pregnancy loss but a variable rate of birth defects. https://t.co/kybCgu3Rlp https://t.co/ckshcgDZbD

• https://bit.ly/3SuqRmb

FDA has approves RINVOQ (upadacitinib) for the treatment of Active Non-Radiographic Axial Spondyloarthritis https://t.co/0HexNAJbtw https://t.co/agSzUVaXSF

• https://on.mktw.net/3z7Qbr5

Metanalyses have shown polypharmacy incr risk of dementia. New Wales study of 33,451 dx'd dementia pts. Freq of polypharmacy (3+ meds) grew over 20 yrs before DDx - from 5.5%, to 41%, to 70%, and 82% just before dx of Dementia. https://t.co/2sz38MYeCl https://t.co/WUdFMcmtTQ

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