Janet Pope Janetbirdope
4 years 3 months ago
#Bestinclass Recurrent #PMR RCT of #sarilumab v placebo. Nearly doubles sustained remission but maybe attenuating effect - flare difference over time? N=118. 🤷♀️ Dunno who I would use it in yet. LB0006 @RheumNow @eular_org #EULAR2022
Janet Pope Janetbirdope
4 years 3 months ago
Positive study NUT when to use the Rx? PMR RCTof 1 g #rituximab once. Over 1 yr with more steroid free remission - curves separate by 21 weeks (steroids off) POS0269 @RheumNow @eular_org #EULAR2023 when to use it-COVID risk, ?prefer IL6i
Urate lowering therapy (ULT) is the backbone therapy for long-term gout treatment and maintenance, but real-world gout management is often imperfect and suboptimal.
David Liew drdavidliew
4 years 3 months ago
ARIAA: saw 18m results #EULAR2022
(alluded to at #ACR21)
High-risk ACPA+ clinically suspect arthralgias
Didn't progress to arthritis:
after 6m abatacept: 92% vs 65%
12m after abatacept stopped: 65% vs 43%
(tighter at points)
How to pick those that benefit?
POS0531 @RheumNow https://t.co/dkf1jU5gx7
Dr. Antoni Chan synovialjoints
4 years 3 months ago
As #EULAR2022 comes to an end, there is still the playback that I am looking forward to watch. Here are my key Psoriatic Arthritis topics and updates from EULAR 2022 https://t.co/KNGGUJuukg @RheumNow
At EULAR 2022, I have been looking at topics and presentations in psoriatic arthritis (PsA). Here are my top picks from this year's meeting.
Dr. John Cush RheumNow
4 years 3 months ago
WATCH: #EULAR2022 - Day 3 Faculty Panel Recap
Drs. Jack Cush, Janet Pope, Aurelie Najm and Yuz Yusof discuss highlights from Day 3 of EULAR 2022.
https://t.co/ExCXY6Xbl4
@Janetbirdope @AurelieRheumo @Yuz6Yusof https://t.co/tIB8QrdYuI
Robert B Chao, MD doctorRBC
4 years 3 months ago
Deucravacitinib: TYK2 inhibitor in pts with active SLE
Phase 2, randomized, double blind, placebo-controlled study
Met primary endpoint SRI response across all doses
No death, MACE, VTE, systemic infections
@RheumNow #EULAR2022 ABST#LB0004 https://t.co/yAM8qUZgee
Robert B Chao, MD doctorRBC
4 years 3 months ago
Sarilumab in pts with relapsing PMR - Phase 3 trial
Sarilumab +14 week steroid taper - higher sustained Remission than w/o sarilumab (28% vs 10%)
Less flare occurrences
Sarilumab noted to have higher incidences of neutropenia, arthralgia
@RheumNow #EULAR2022 ABST#LB0006 https://t.co/SeetkBsYI3
Dr. Antoni Chan synovialjoints
4 years 3 months ago
Witholding MTX after both doses or only after the second dose of ChAdOx1 vaccine yields higher antibody repsonse compared to continuing MTX. Witholding MTX after second dose reduced the risk for flare. Data from MIVAC 1 and 2 #EULAR2022 @RheumNow LB https://t.co/GfL4eDXchb
Dr. Antoni Chan synovialjoints
4 years 3 months ago
In bDMARD-naive patients with PsA, the 24 week efficacy and safety of BKZ in BE OPTIMAL LB0001 by McInnes et al. At Week 16 ACR50 44% BKZ, 10% PBO, ADA 46%. PASI 90 at Week 16, 62% BKZ, PBO 3%, ADA 41% and benefit continued to Week 24 #EULAR2022 @RheumNow https://t.co/LRZoxzM57J
TheDaoIndex KDAO2011
4 years 3 months ago
Great visual on how #socialmedia can further research and medical education #eular2022 @rheumnow @UnaMakris
@UTSWRheum https://t.co/3OiQ6CggnA

