Dr. John Cush RheumNow
4 years 4 months ago
Study of PCP Dx irritable bowel dz; 459 randomised to 8 weeks of oral antispasmodics or diet (low fermentable oligosaccharides, disaccharides, monosaccharides and polyols (FODMAP). Better responses with diet (71% vs 61%; p=0.03). Better adherence w/ diet. https://t.co/gmn45yQmuB https://t.co/8SP5Vfx71z
Dr. John Cush RheumNow
4 years 4 months ago
Nature study shows videoconferencing inhibits creativity (idea generation) because it focuses communicators on a screen, which prompts a narrower cognitive focus. Yet, virtual interaction might increase decision quality. https://t.co/0yTEcmtKye https://t.co/ruwOj9qJ9J
Dr. John Cush RheumNow
4 years 4 months ago
Pregnancy outcomes in systemic sclerosis (SSc) studied in 154 pregnancies from SSc, SLE, APS, & controls (2008 to 2019). Adverse Preg Outcomes APO significantly higher in SSc vs HC (61% vs 10%) w/ more miscarriages, preeclampsia, SGA & preterm births https://t.co/P3uksmJy6V https://t.co/nTtgwjdGgL
While tumour necrosis factor inhibitors (TNFi) have been shown to alter/retard X-ray outcomes in peripheral inflammatory arthritis, the inhibitor effects of TNFi on axial skeletal progression in spondylitis has been difficult to prove, owing to difficulties in study design, identifying best cohorts and a presumed slower rate of change in the spine.
Dr. John Cush RheumNow
4 years 4 months ago
Miss this week’s Tuesday Night Rheumatology? We’ve got you covered.
https://t.co/TuBeZTWG9d https://t.co/qWWBSXKKSW
Dr. John Cush RheumNow
4 years 4 months ago
Perplexing Oligoarthritis, +FHx, But no psoriasis
QD Clinic is sponsored by RheumNow's PsA All the Way Campaign in April 2022
https://t.co/ljZ1cStNTy https://t.co/8RMFFWjDEP
The efficacy of ultrasound guided intra-articular hip injection of corticosteroid in adult hip osteoarthritis (HOA) was shown to be effective when added to conventional current treatment. But was this a clinically meaningful outcome?
Playback now available! Watch our Tuesday Nite Rheumatology, held April 26th, 2022, which featured a Journal Club panel discussion about two important studies.
Dr. John Cush RheumNow
4 years 4 months ago
SLE (n=2428) pts followed for 224,295 Pt-months- Osteonecrosis seen in 122 pts (6.5/1,000 PtYrs). Higher ON risk - African Americans (2x), Male (1.8x), smokers (1.5x). Higher Rates w/ high dose prednisone (not pulse or IM TCA) https://t.co/omU9Z1Z3kU https://t.co/wceGoCcUBV
When balancing all these disease domains, individual phenotypes, and comorbidities, sometimes treatment decisions can feel like tossing a coin. Fortunately, numerous guidelines have been published to help us do better than tossing a coin…or do they?
Dr. John Cush RheumNow
4 years 4 months ago
Systematic literature review of studies where steroids were used as initial "Bridge Therapy" in RA patients - included 10 studies, but only 4 RCTs w/ protocolized discontinuation - these showed 22% were still on GC @ 12 mos, 10% @24 mos https://t.co/aRLhptAASe https://t.co/lg4msIyQfc
Dr. John Cush RheumNow
4 years 4 months ago
Watch: Dr. Ritchlin discusses Future Discovery and Targets.
https://t.co/MOQjXWd6tc https://t.co/EQWBnL9jzI
Dr. John Cush RheumNow
4 years 5 months ago
Spanish BIOBADASER registry real world performance of secukinumab in 639 pts w/ #PsA & spondyloarthritis (axSpA, AS, NR axSpA) showed imprved Dz activity at 1 yr & maintained or increased 2 & 3 years. Retention rates best when SEC used 1st biologic https://t.co/MAE3BhLlRg
Dr. John Cush RheumNow
4 years 5 months ago
Cardiovascular risk (CVR) was assessed in Psoriasis (#PSO) & #PSA in multiracial population in S Brazil using the Framingham Risk Score. Compared to controls PSO & PSA had higher FRS (16.3 & 18 vs 10.6) and also increased with age. highttps://bit.ly/3k7ySi8

