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Increased Risk of MACE in Lupus After Noncardiac Surgery: Dr. Kathryn Dao ( @KDAO2011) discusses abstract #0128 presente

Dr. John Cush RheumNow

4 years 10 months ago
Increased Risk of MACE in Lupus After Noncardiac Surgery: Dr. Kathryn Dao ( @KDAO2011) discusses abstract #0128 presented at #ACR21 annual meeting. https://t.co/HOVLrhBbuu https://t.co/MAItCSHMIb
Hitting the home stretch, day 3 presentations were big! Here are a few of my favorites: secukinumab efficacy in juvenile PsA; VEXAS - predicting poor outcomes; and the FDA Safety Update session.
Should we start considering therapeutic drug monitoring when prescribing TNFi for treatment of our rheumatologic conditions?
RT @ericdeinmd: #ACR21 Ab#1941: ORAL Surveillance VTE risk
▶️Tofa 10 BID risk > 5 BID > TNFi for VTE, DVT, PE

Eric Dein ericdeinmd

4 years 10 months ago
#ACR21 Ab#1941: ORAL Surveillance VTE risk ▶️Tofa 10 BID risk > 5 BID > TNFi for VTE, DVT, PE ▶️Age, male, obesity, HTN, h/o VTE, oral contraception/HRT, steroids, antidepressants were risk factors @RheumNow https://t.co/JOKNyYVZfX https://t.co/mTkgkwPIT6
RT @RichardPAConway: Comparative risks of skin SCC and BCC with different DMARDs. Abatacept appeared worst, HR 2.18, but

Richard Conway RichardPAConway

4 years 10 months ago
Comparative risks of skin SCC and BCC with different DMARDs. Abatacept appeared worst, HR 2.18, but may be residual confounding due to burden disease/comorbidities. Abstr#1942 #ACR21 @RheumNow https://t.co/UzOwuKKFmX
RT @RichardPAConway: Therapeutic drug monitoring ⬆️ infliximab efficacy in RCT. 17.6% improvement in sustained disea

Richard Conway RichardPAConway

4 years 10 months ago
Therapeutic drug monitoring ⬆️ infliximab efficacy in RCT. 17.6% improvement in sustained disease control. Consistent across all rheumatic and non-rheumatic diseases. Abstr#1946 #ACR21 @RheumNow https://t.co/D1Ppb58fB8
RT @Janetbirdope: Who declines most with #scleroderma #ILD - early dcSSc, ⬆️CRP, ⬆️mRSS all w more ⤵️FVC. Re

Janet Pope Janetbirdope

4 years 10 months ago
Who declines most with #scleroderma #ILD - early dcSSc, ⬆️CRP, ⬆️mRSS all w more ⤵️FVC. Results verified in SENSIS trial of SSc ILD where #nintedanib was superior to placebo abst#1846 #ACR21 @RheumNow https://t.co/eckUj0qwch
RT @ericdeinmd: Thank you @AhmadSherbini for discussing his #ACR21 research on @RheumNow on Abs#1444 - Can we predict wh

Eric Dein ericdeinmd

4 years 10 months ago
Thank you @AhmadSherbini for discussing his #ACR21 research on @RheumNow on Abs#1444 - Can we predict which patients are most likely to have nausea or alopecia intolerance to MTX? https://t.co/I5WmCECq7v
RT @RichardPAConway: GRA @rheum_covid data presented by @mugartegil. African-American and Hispanic individuals with SLE

Richard Conway RichardPAConway

4 years 10 months ago
GRA @rheum_covid data presented by @mugartegil. African-American and Hispanic individuals with SLE have MUCH worse COVID-19 outcomes. Likely related socioeconomic and health disparities. Abstr#1933 #ACR21 @RheumNow https://t.co/YUoOeIxN7O
RT @RichardPAConway: Hospitalisation for heart failure ⬆️ in inflammatory diseases. RA>PsA>AS>PsO . HRs 1.1

Richard Conway RichardPAConway

4 years 10 months ago
Hospitalisation for heart failure ⬆️ in inflammatory diseases. RA>PsA>AS>PsO . HRs 1.1-1.6 compared to general population. Abstr#1925 #ACR21 @RheumNow https://t.co/kKlGQM5Tcg
RT @ericdeinmd: #ACR21 Ab#1939: Tofa CV Outcome (STAR-RA)
▶️Pooled data does not show ⬆️ risk of CVD
▶️Trend

Eric Dein ericdeinmd

4 years 10 months ago
#ACR21 Ab#1939: Tofa CV Outcome (STAR-RA) ▶️Pooled data does not show ⬆️ risk of CVD ▶️Trend in pts w prior CVD -HR 1.27 (0.95-1.7), cannot r/o CVD risk in pts w risk factors Less clear than oral surveillance data, but concerns in those w risks https://t.co/JOKNyYVZfX @Rheumnow https://t.co/GGYJfxcqhc
RT @RichardPAConway: ORAL Surveillance malignancy risk @RADoctor . Numerically higher at both doses tofacitinib compared

Richard Conway RichardPAConway

4 years 10 months ago
ORAL Surveillance malignancy risk @RADoctor . Numerically higher at both doses tofacitinib compared to TNFi . Abstr#1940 #ACR21 @RheumNow https://t.co/uc2k5EaiRq
RT @drdavidliew: STAR-RA, CV risk
large insurance datax3

tofa vs TNFi
all comers: HR 1.01 (0.83-1.23)
one CV RF + any M

David Liew drdavidliew

4 years 10 months ago
STAR-RA, CV risk large insurance datax3 tofa vs TNFi all comers: HR 1.01 (0.83-1.23) one CV RF + any MTX: HR 1.24 (0.90-1.69) prev CVD: HR 1.27 (0.95-1.70) not sig but surely okay to say baseline CV risk + tofa makes me a little nervous? @SeoyoungCKim #ACR21 ABST1939 @RheumNow https://t.co/LmmL5zgv9u
RT @drdavidliew: So time for ORAL Surveillance, malignancy and VTE risk.

I'll go through some of the key points in this

David Liew drdavidliew

4 years 10 months ago
So time for ORAL Surveillance, malignancy and VTE risk. I'll go through some of the key points in this thread #ACR21 ABST1940, ABST1941 @RheumNow https://t.co/pbjM2sFAXz
RT @Janetbirdope: Why is there more CHF in #RheumatoidArthritis ? Also dose response between highest inflammation RA the

Janet Pope Janetbirdope

4 years 10 months ago
Why is there more CHF in #RheumatoidArthritis ? Also dose response between highest inflammation RA the PsA then axSpA then PsO. ?Cytokine profile varying with disease and maybe CRP. Who knows. Abst#1925 #ACR21 @RheumNow https://t.co/JIH3qwkLpx
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