Functional MRI eval neuro-connectivity in 78 SLE pts Cognitive impairment occurred in 48%; pts had: 👉longer disease duration 👉likely +LAC 👉abnormal fMRI 👉>blood brain barrier permeability #ACR21 #Plenary Abstr# 0456 @rheumnow https://t.co/WI5CD73rvM

How about lipoprotein a as a potential biomarker for poor renal outcomes in #lupus? Results of this study by Dr @CaoilfhionnMD and her group show that ⬆Lp(a) is strongly associated w/ proteinuria, ⬇ eGFR and ⬆PGA. Interesting🤓 @RheumNow #ACR21 abs0327 https://t.co/MLgJ1tPJMp

#ACR21 Abst#0155 ⭐︎ Tenosynovitis on MRI hand/foot in ACPA(-) undifferentiated oligo-arthritis pts is predictive of RA ➡️NPV 93%, Se 85% ⭐︎ BM edema not prognostic of RA development Do you already use MRI to help detect early RA? @Rheumnow https://t.co/mpageAYeT2

• The Additional Value of MRI in Diagnosis of Rheumatoid Arthritis in Undifferent…

#ACR21 Many faces of cell death Netosis in APS and #SLE NETs and APS 🕸️NETs are prothrombotic🕸️ https://t.co/FG3VNbQPzh

Pts with hospitalization from #SLE often do NOT have a f/u visit within next 2 weeks. 2/3 NO timely fu esp poor, young non-White& do worse. Is it due to fact that no one gets discharge summary or admission note or discrimination or health system prob #abst0464 #ACR21 @RheumNow

Targeting the HUGE dilemma!🎯 #Psoriatic vs Erosive #OA PsA 👉 Fluffy bone formation(enthesitis of phalanges) 👉 Marginal erosions(vs central) 👉 Many jts in same digit(ray inv) 👉 Periarticular SOFT tissue swelling (dactylitis). 👉 NOT much hand OA #ACR21 RadiologyBootCamp https://t.co/OQLPoeRLny

Abstract 0444- Dr. Gupta ⭐️COVAD Study - ❗️18000 global pt survey looking at AE after COVID vaccination in Autoimmune disease 1227 IIM pt total- more injection site pain, headache, rash, fatigue in DM #ACR21 #ACRAmbassador https://t.co/s4Fc5c9Kln

Blood Brain Barrier leakage correlates w/ CNS dysfunction in SLE - study by John Hanley of 78 SLE pts. CNS impaired in 48% SLE (more likely LAC+, APL+) correlated w BBB (10-30%) leaks. #ACR21, Abstr# 0456 https://t.co/DyUB2TU4pS https://t.co/Sd1tr0BF2H

• https://bit.ly/3nXohI4

Also DESIR cohort: male gender & higher education independently assoc'd w/ lower hazard of Sick Leave (SL.) Older age & higher disease activity assoc'd w/ more SL. AxSpA dz activity & SES play roles in SL predictions. Abs 0380 #ACR21 #RheumNow @RheumNow https://t.co/1lRhDAu7Ug https://t.co/RRG6BeUqvs

• Sick Leave and Its Predictors in Early Axial Spondyloarthritis: The Role of Cli…

ARRIA Study: Abatacept vs PBO in pre-clincial RA (N98) pts x 6 mos. Showed ABA prevented arthritis (8 vs 35%), improved MRI inflamm (61 v 31%), fewer D/C (14 vs 43%) - all signif. Further FUV 12 mos off therapy still significant at 18mos #ACR21 Abstract 0455 https://t.co/ZxFUj6KfLT

Pearls on Rheum imaging: 👉CPPD is not erosive 👉SC joint in OA is common (hard to image) 👉AC joint is 1st place OA affects shoulders (not GH) 👉Neuropathic OA progress rapidly, look at the TMTs 👉Get more views if you aren't seeing what you need #ACR21 Radiology Bootcamp

Another one from Dallas! Congrats, Dr. Limanni! #ACR21 https://t.co/Rs3muuFQKh

Dr Oster presenting on IL-23 inhibitor Risankizumab in PsA. No surprises here, it works. We need comparative efficacy trials! Abstr#0453 #ACR21 @RheumNow https://t.co/mj8TeCqEcg

Plenary I 0454 LN mortality in the US & disparities using CDC WONDER data 1999-2019 "LN mortality exhibited profound disparities by race/ethnicity and place of residence" https://t.co/UtMzaiL14D #ACR21 https://t.co/C3fuq8anvR

• Lupus Nephritis Mortality in the United States, 1999-2019: Profound Disparities…

#ClinicalPearl What lasts longer/⬆️retention in sero+ RA: Abatacept or TNFi or JAKi? #ACR21 abst#0463 @RheumNow Adjusting for confounding incl line of Rx / past bio Rx, #abatacept wins. But data not stratified for bio naive or exposed. Not sure if that would alter results https://t.co/1dEQncwPQF