Dr. John Cush RheumNow
5 years 2 months ago
Tofacitinib shown to work very well in ankylosing spondylitis.
@RWCSmtg @JointMD https://t.co/bx5FS9BSDZ
Dr. John Cush RheumNow
5 years 2 months ago
Throwback Tweet: Hello 2021 and new drug price hikes - on average a 4.2% hike in over 500 drugs (past years saw an avg hike ~5%). Increases include Cosentyx 7%, Humira & Rinvoq 7.4%, Orencia 4.5%, Taltz 5%, Actemra 3%, Benlysta 5%, Xeljanz 4.9% & Cimzia 4%
Dr. John Cush RheumNow
5 years 2 months ago
Great Gout Teaching points. Here's my 2 cards on how to Stop #gouta https://t.co/R3EhYFusKf
Dr. John Cush RheumNow
5 years 2 months ago
Septic arthritis MIMICs (all presenting as acute monoarthritis) - consider: cellulitis, bursitis, abscess, osteonecrosis, gout, pseudogout, Lyme, Osteomyelitis, reactive arthritis, Lyme disease,, Rheumatoid arthritis, & Transient synovitis (kids) https://t.co/uNirAcoBds
Dr. John Cush RheumNow
5 years 2 months ago
Comparison of MSU crystal ID, DECT scanning and US to Dx gout - study of 147 pts. Compared to the gold standard (MSU ID), Feet/ankles (87% sensitivity; 100% specificity) or knees DECT (91%; 87%) alone had best Dx accuracy. US was inferior to DECT. https://t.co/2Hiu7YhLo8
Dr. John Cush RheumNow
5 years 2 months ago
Hands-Down Rheumatology - Sarcoidosis usually presents as a monarthritis or oligoarthritis. Late sarcoid arthritis affects knees, ankles, fingers (dactylitis). Bony lesions show honeycomb trabecular pattern).
https://t.co/lmXBbJz6ts https://t.co/oDYrBiPuIX
Dr. John Cush RheumNow
5 years 2 months ago
Pirfenidone, studied in 127 pts w/ CVD/CTD ILD, fibrotic interstitial pneumonia, chr hypersensitivity pneumonitis, & asbestoslung fibrosis. Pirefenidone had significantly less FVC% decline compared with placebo (p=0·043)
https://t.co/H1s6ut4NhG
Dr. John Cush RheumNow
5 years 2 months ago
263 RA patients with ILD were treated w/ Abatacept (ABA mono, ABA+MTX or ABA+nonMTX) - all improved their DAS28, stablized their FVC, DLCO, CHest CT; Only difference was that steroid sparing best when ABA used in combo. https://t.co/1dGufcKsha
Dr. Jack Cush reviews and discusses the news and journal reports from the past week on RheumNow.com.
The TOMORROW study assessed the relationship between diet and disease activity in rheumatoid arthritis (RA) patients and has shown that RA patients are more likely to have higher inflammatory diets, but that a change to an anti-inflammatory diet resulted in lower disease activity scores.
Dr. John Cush RheumNow
5 years 2 months ago
Vaccinated COVID-19 pts appear less contagious; report from Israel - among 650,000 received two-doses of Pfizer vaccine, 2,897 later tested positive for COVID-19, but nasal swab samples showed 4-fold less virus - hinting protection
https://t.co/UBE4q5T2Ht https://t.co/OOgWoqdkdt
Dr. John Cush RheumNow
5 years 2 months ago
Rifampin is safest! 2 RCTs of 6485 latent TB pts compared 9 mos of isoniazid vs 4 mos of rifampicin. RIF had half the adverse events compared to INH; roughly half the rate of rash (1.5% v 2.7%); No grade 3-4 hepatotoxicity w/ RIF, compared 6%) w/ INH
https://t.co/n1cVKyEPf6
Dr. John Cush RheumNow
5 years 2 months ago
Plasmapheresis Indications : TTP, HUS, Cryoglobulinemia, Hyperviscosity, Myasthenia gravis, Goodpastures, Catastrophic APL Syn, Chr inflamm demyelinating polyneuropathy, Removal of drugs/toxins, Alveolar hemorrhage, ANCA vasculitis (questionable)
https://t.co/uph9Eprlvc https://t.co/FPLOgzZpfB
Dr. John Cush RheumNow
5 years 2 months ago
These companies do auto-inflammatory gene testing in the USA.
@RWCSmtg https://t.co/89bWd0SiAI
2020 was historic, memorable and game-changing. Under the cloud of COVID-19, there were many significant and memorable advances and setbacks for the rheumatology world. In our accounting of most read articles for 2020, (not surprisingly) 17/20 were COVID-related. Below, are our top news items that rheumatologists should recollect and integrate into clinical standards for 2021 and beyond.
