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Avacopan - Is it Really a Win for ANCA-Associated Vasculitis?

The NEJM has reported the results of a study showing that

Dr. John Cush RheumNow

5 years 7 months ago
Avacopan - Is it Really a Win for ANCA-Associated Vasculitis? The NEJM has reported the results of a study showing that avacopan, a C5a receptor inhibitor, is as effective as steroids at treating patients with ANCA-AAV. https://t.co/vWmhEhX8Z3 https://t.co/omXpouPKoJ
SF analysis usually confirms dx, but changes dx 14%. 264 SF samples showed MSU crystals in 89% gout, 9% of CPPD pts. CPP

Dr. John Cush RheumNow

5 years 7 months ago
SF analysis usually confirms dx, but changes dx 14%. 264 SF samples showed MSU crystals in 89% gout, 9% of CPPD pts. CPP crystals found in 54% of CPPD, 43% of OA & 7% of gout pts. Ca hydroxyapatite seen 1/3 RA, 1/2 OA & 2/3 CPPD https://t.co/B8UkHagXK3 https://t.co/UTncLo6Fyu
Alveolar Hemorrhage and Mortality in Lupus

Metanalysis of patients with DA), show this to be a rare and life-threatenin

Dr. John Cush RheumNow

5 years 7 months ago
Alveolar Hemorrhage and Mortality in Lupus Metanalysis of patients with DA), show this to be a rare and life-threatening complication of SLE, that is more apt to affect older, severe lupus patients with active infection. https://t.co/EILQZTYYjk https://t.co/kDAFuYIJuH
Dr. Jack Cush reviews nearly a dozen news and journal reports from the past 2 weeks on RheumNow.com, including the ACR's new COVID-19 vaccine guidance for patients with rheumatic disease.
QD Clinic - Hemoptysis and SLE
A recent metanalysis of studies suggest you may be able to use certain clinical factors to stratify cancer risk in patients with idiopathic inflammatory myopathies (IIMs).
The NEJM has reported the results of a study showing that avacopan, a C5a receptor inhibitor, is as effective as steroids at treating patients with antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis (AAV).
Email Survey study of HSS rheumatic pts 7,094 responded 1,547 were women (18-50yrs) & 61 (4%) were pregnant during

Dr. John Cush RheumNow

5 years 7 months ago
Email Survey study of HSS rheumatic pts 7,094 responded 1,547 were women (18-50yrs) & 61 (4%) were pregnant during COVID. COVID prevalence was similar in PREG vs nonPREG (8% vs.9% ), PREG COVID pts had shorter Sxs, more loss taste/smell. https://t.co/4HDuXbZVrs
2021 RWCS Review podcast is now available- #RWCS Available on SoundCloud and Apple/Android https://t.co/eLk3vqoAT8 ht

Dr. John Cush RheumNow

5 years 7 months ago

2021 RWCS Review podcast is now available- #RWCS Available on SoundCloud and Apple/Android https://t.co/eLk3vqoAT8 https://t.co/U8YjToQlIS

Very high levels of IL-18 IL-18 (> 10 000 pg/ml) is associated with Macrophage Activation syndrome (with systemic JI

Dr. John Cush RheumNow

5 years 7 months ago
Very high levels of IL-18 IL-18 (> 10 000 pg/ml) is associated with Macrophage Activation syndrome (with systemic JIA) as well as primary and secondary Hemophagocytic lymphohistiocytosis (HLH) https://t.co/dotoaYbuPd
On March 24, 2021 the FDA Arthritis Advisory Committee and Drug Safety .... Committees will meet online to will discuss

Dr. John Cush RheumNow

5 years 7 months ago
On March 24, 2021 the FDA Arthritis Advisory Committee and Drug Safety .... Committees will meet online to will discuss biologics license application, for tanezumab, from Pfizer, for the proposed treatment of moderate to severe osteoarthritis in adults https://t.co/NSlutqdHzu
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