Dr. John Cush RheumNow
6 years ago
Study of 193 Axial SpA pts with TNF inhibitor switching shows, using stringent outcome measures (ASDAS-ID) shows odds of responding to 2nd TNFi best w/ secondary TNFi failure (OR 7.3) or adverse events (OR 9.1), compared to primary TNFi failure. https://t.co/kpDelzBYRe
Dr. John Cush RheumNow
6 years ago
Study of 222 RA pts on MTX given anti-GMCSF (otilimab) 22·5 mg, 45 mg, 90 mg, 135 mg, 180 mg, or PBO weekly x 5 wks, then EOW. @wk 24 DAS28-CRP <2·6 5%, 16%. 19%, 14%, 14% respectively and 3% in PBO. Otilimab failed to meet primary endpoint. https://t.co/14QqyeTcuP
Dr. John Cush RheumNow
6 years ago
Comparison of 34,128 COVID and 84,585 influenza pts; COVID-19 patients have been more typically been male, younger, and have fewer comorbidities and lower medication use than flu. (data from USA, South Korea, Spain) https://t.co/VUzVxFdBra
Dr. John Cush RheumNow
6 years ago
Lockdown worsening; UK survey 678 patients musculoskeletal diseases pts in late April 2020 shows 53% worsening of Sx; 1/3 had clinic/hosp access probs problems & most (88%) had no probs w/ getting meds; but 44% needed others to help them get meds. https://t.co/3efmTdHhQx
Dr. John Cush RheumNow
6 years ago
Among 4766 mental health pts admited for Psychosis; 19% ANA tested and only 135 had a positive ANA >=1:160. (15% of those tested). Only 4 met 2019 ACR/EULAR criteria for SLE, and 2/4 met criteria for NPSLE. NPSLE prevalence was 1.5% in ANA+ psychosis Pts. https://t.co/c5C1VQaQAI
A subanalysis of the CANTOS trial suggests that inhibition of interleukin-1β (IL-1β) can reduce rates of incident hip or knee replacement (THR/TKR) surgeries.
Denosumab is effective in osteoporosis when used on schedue, but research suggests that discontinuation leads to rapid reversal of effect; a new observational study has shown that delays in denosumab administration of more than 16 weeks results in an increased vertebral fracture risk, according to a report in Annals of Internal Medicine.
NM Rheumatology NM_Rheumatology
6 years ago
How pregnancy impacts nr-axSpA disease activity can vary from one woman to another, according to Eric Ruderman, MD, “I’ve had some patients who are better during pregnancy, and some who aren’t,” says Dr. Ruderman. Learn more about pregnancy and nr-axSpA:
https://t.co/mC6YcG5lIx
NYT Health NYTHealth
6 years ago
To quash the virus, the immune system unleashes an arsenal. Sometimes these weapons turn inward and destroy healthy tissues. Combatting this friendly fire has become as crucial a part of the Covid-19 treatment strategy as subduing the virus itself. https://t.co/FrxVfSleEH
WOMEN IN RHEUM AWIRGROUP
6 years ago
The AWIR San Diego, CA Virtual Summit
CME Accredited : Worth 3.0 CEU Credits™
October 11th | Register Now:
https://t.co/4vSqD0bxpk
Join us on October 11th as we discuss Spondyloarthritis & the Spine, Telehealth regulatory updates, and more! For MD, NP, PA & PharmD Health Prof. https://t.co/QLXVJYjTD2
Dr. Dinesh Khanna sclerodermaUM
6 years ago
1) If you are have diffuse scleroderma and have previously participated in a clinical trial, we need your help! You will be asked to watch video tutorial and answer a survey which will take you 20 minutes to complete. the study is supported by @WeAreSRUK @scleroderma @srfcure
Jeff Sparks jeffsparks
6 years ago
Incredible lecture on the highest of therapeutics for rheumatoid arthritis by @BrighamWomens Dr Michael Weinblatt. Love this screen shot of A to Z for therapies prior to the methotrexate era. Z=Zero therapy (do nothing). Incredible advances since then! https://t.co/AOIMBJiulo
Dr. John Cush RheumNow
6 years ago
Classic bony erosion of gout is a punched-out, lytic lesion w/ a sclerotic margin & overhanging edge -- called a G sign, rat-bite erosion or the Martel sign, named after famed U MI radiologist Dr. William Martel who 1st described this gouty erosion in 1968 https://t.co/WJJUnjnnfl
