Current ACR and EULAR guidelines list TNF-inhibitors (TNFi) abatacept, rituximab, and tocilizumab as being equally effective after methotrexate or as second line therapies when treating rheumatoid arthritis. An analysis from the Swedish Rheumatology Register shows that the non-TNFi biologic DMARDs (bDMARDs), in particular tocilizumab and rituximab, are more effective than TNFi.
Rheumatology has a comprehensive overview of methotrexate (MTX) and the risk of lung injury, MTX-related pneumonitis and interstitial lung disease (RA-ILD) with rheumatoid arthritis (RA). Past reports suggest the frequence of MTX-pneumonitis to be between 0.3 and 11.6%; recent studies suggest it may be much lower.
Dr. John Cush RheumNow
6 years 9 months ago
Review of 541,744 total knee replacement (TKR) in Australia (1999-2017) finds lower revision rates in RA vs. OA, but increased risk of infection in RA (esp. males) https://t.co/XA1jLoOEBo
Dr. John Cush RheumNow
6 years 9 months ago
I would never allow my patient to self medicate or regulate their Prednisone or MTX, immunosuppresives or biologics. It's what they don't know that will hurt them.
Dr. John Cush RheumNow
6 years 9 months ago
Doctors know medicines. But when a doctor treats him/herself the adage is that he/she has a fool for a patient. Remind your patients of this next time they try to test themselves with out the input if an expert
Dr. John Cush RheumNow
6 years 9 months ago
Is the Serious infection (SIE) risk different between TCZ and TNFi? Not when used after failing 1 TNFi; But for biologic initiators, SIE risk was higher in TCZ compared to TNFi or ABA (based on claims data from 16074 TCZ matched to 33109 TNFi initiators https://t.co/ZHVWF9fIHF
Dr. John Cush RheumNow
6 years 9 months ago
Kaiser Permanente study of 1,956 adult #SLE patients shows that only 58% of lupus pts were ≥80% adherent to hydroxychloroquine. Only age and increasing visits were predictive. Not predictive were the rheumatologist, center or socioeconomic factors. https://t.co/m0oN1OC9bn
Philip Robinson philipcrobinson
6 years 9 months ago
Since fasting is so hot right now, here is a hot off the press @NEJM review of it => Effects of Intermittent Fasting on Health, Aging, and Disease | NEJM https://t.co/Ijc0NSFa9s
Tuhina Neogi, MD, PhD Tuhina_Neogi
6 years 9 months ago
Should we keep our patients with #gout on colchicine indefinitely (if no contraindications/intolerances) for their higher risk of MI/CVD? https://t.co/4bQds3u1oL
American College of Rheumatology ACRheum
6 years 9 months ago
The ACR and EULAR have developed the first-ever international set of classification criteria for IgG4-RD, which was established and tested using a data-driven approach and multicriterion decision analysis – details: https://t.co/rI8dRM8kmO https://t.co/sTJ360Ouxb
Mike Putman EBRheum
6 years 9 months ago
Congrats & welcome new rheum fellows!
Another competitive year, with rheum match rate (71.3%) behind GI (62.8%) but similar to CARDS (72.8%) & HONC (77.4%)
Thankfully better than last year (65.1%) but still a lot of (well deserved!) excitement for the field! https://t.co/QDD5VCD8Rv
NYT Health NYTHealth
6 years 9 months ago
Patients and insurance companies in the United States pay higher prices for medications, imaging tests, basic health visits and common operations. https://t.co/oQrCSOE58j
ACP ACPinternists
6 years 9 months ago
#DidYouKnow Sir #WilliamOsler died ☠️ of what he called “the old man’s friend” (#pneumonia)? Learn more about the “father of #InternalMedicine” during the 💯th anniversary of his death https://t.co/0O61Qctouq. #IMProud @mcgillu @UniofOxford @JohnsHopkins @Penn @RoySocMed https://t.co/1ZS79pZrhx
American College of Rheumatology ACRheum
6 years 9 months ago
The #Rheumatologist: Ellen M. Gravallese, MD, Begins ACR Presidency → https://t.co/ZO6ilPG0lk
Dr. Dinesh Khanna sclerodermaUM
6 years 9 months ago
Exciting work by colleagues in US, led by NIH. https://t.co/bGB75bOGFB. immunodominant peptides of topo 1, fibrillarin, and centromere protein A are homologous to viral protein sequences from the Mimiviridae and Phycodnaviridae families, suggesting molecular mimicry.@NIH_NIAMS
