Dr. John Cush RheumNow
7 years ago
Analysis of retail pharmacies and drug costs show that, compared to large chain pharmacies, big box was 48% cheaper, followed by grocery-based (18% cheaper), next small chain (51% higher), and independent pharmacies (61% higher) https://t.co/jlQnNboiAR
Dr. John Cush RheumNow
7 years ago
Approximately 20–30% of IBD patients will develop spondyloarthritis. Using a survey tool on 244 IBD pts they found 21% with sufficient criteria to suspect SpA - Other risk factors included being female, Crohn's, prior DMARD or biologic drug use. https://t.co/9Ail7syLmB
Adam Cifu adamcifu
7 years ago
One of my favorite things about writing "health humanities" pieces for journals are the gracious, thoughtful, insightful notes I get from fellow docs. This one arrived in my inbox this AM. Humbling in its perfection.
In response to this article: https://t.co/9uPvPDOPAI https://t.co/85usMOPqlb
Adam Cifu adamcifu
7 years ago
Felt the need to update my 10 commandments. Fortunately, on twitter, commandments are not written in stone. https://t.co/Rt9YDW8lFh
Gabe Charbonneau, MD gabrieldane
7 years ago
"Physicians don’t hate technology – they have smartphones, fitness trackers and tablets just like everyone else – what they hate is bad technology."
Truth. #fightburnout
https://t.co/qTG0jZFtDL
Dr. John Cush RheumNow
7 years ago
Survey for Rheumatologists - You would use an MRI in an RA to assess what?
Dr. John Cush RheumNow
7 years ago
Kaiser study of 1956 SLE patients shows only 58% of were adherent (≥ 80%) to hydroxychloroquine; not predicted by the Rheum, hospital or socioeconomics. Risk factors for nonadherence included age, being white, # of Rheum visits/yr. https://t.co/qRdJRGvRAr
While the efficacy and safety of interleukin 1 (IL-1) inhibitors (e.g., anakinra) in the acute management of gout and pseudogout has been repeatedly shown, the cost efficacy of such biologic therapy has rendered it impractical for most. A new retrospective study has shown that IL-1 inhibitors may be effective and appropriate for some medically complex, hospitalized patients with acute gout or calcium pyrophosphate crystal arthritis.
The NEJM reports on a randomized comparison of hemiarthroplasty and total hip arthroplasty in displaced femoral neck fractures and shows no difference in function and quality of life over 24 months.
Dr. John Cush RheumNow
7 years ago
Retrospective claims study shows that higher ACPA and RF titers were independently associated with 60-78% increased mortality in established RA; the association persisted in when Rx with DMARDs, but not with biologics. https://t.co/hHJx4alNIQ
Dr. John Cush RheumNow
7 years ago
Study of 101 RA pts w/ baseline Cardiac CT; after median of 83 mos, 48% had progression of plaque; predicted by older age, inflammation & prednisone (p<0.05). Coronary Art. Calcium progressors were older, obese, HTN w/ more inflammation https://t.co/hJRhfja0yk
Dr. John Cush RheumNow
7 years ago
Tofacitinib therapy is being studied (not yet approved) in several dermatologic conditions - psoriasis, alopecia areata/universalis, vitiligo, atopic dermatitis and dermatomyositis. https://t.co/Ez3u95Eh7K
Dr. John Cush RheumNow
7 years ago
A&R reviews the inflammasome in autoimmune diseases. Pattern recognition recpt induce inflammasome activation, pro-caspase-1 converts to caspase-1 convertin pro-IL-1β and pro-IL-18 active IL-1β and IL-18; seen in RA, SLE, gout, Sjogrens https://t.co/JGadiEWQWf
The NEJM reports the results of a one year trial wherein ustekinumab (UST) was shown to be effective at inducing and maintaining remission in patients with moderate-to-severe ulcerative colitis. Ustekinumab, currently approved for use in psoriasis, psoriatic arthritis and Crohn's disease, is a monoclonal antibody against the p40 subunit of interleukin-12 and interleukin-23.
Dr. John Cush RheumNow
7 years ago
CDC advises against vaping with marijuana, noting that up to 77% of 805 cases and 12 deaths from lung disease tied to vaping with THC https://t.co/dtDvMJ1dlA
