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The July 16th edition of JAMA reviews the highly prevalent problem of hip fractures - a major global health burden: 14.2 million occur worldwide annually (280,000 in the US), with global incidence higher in women (833.9/100,000) than men (510.0/100,000). Lifetime risk at age 50 is 22.9% for women, 10.7% for men. Mortality is substantial.
Cerebral atrophy is common in SLE - assoc w/ age (OR 1.1), higher education (0.22), NPSLE (OR 4.6), cognitive impairmen

Dr. John Cush RheumNow

1 month 3 weeks ago
Cerebral atrophy is common in SLE - assoc w/ age (OR 1.1), higher education (0.22), NPSLE (OR 4.6), cognitive impairment & lower dsDNA titers. 70 pts (mean age 40, Dz dur 12yrs). Cerebral atrophy 53% (mostly 76% mild). https://t.co/ewRmNj8zNA https://t.co/yT8TCXZREA
$2 Million in Research Grants for Juvenile Arthritis

In July, the Arthritis Foundation and the Childhood Arthritis and

Dr. John Cush RheumNow

1 month 3 weeks ago
$2 Million in Research Grants for Juvenile Arthritis In July, the Arthritis Foundation and the Childhood Arthritis and Rheumatology Research Alliance (CARRA) awarded $2 million in research grants to support physician-led research in pediatric rheumatology. https://t.co/1GewFUMauu
British Dermatology Biologics registry (BADBIR) 18976 #PSO pts had incidence serious infxns (SIE) 28 SEI/1000 Pt-Yrs; hi

Dr. John Cush RheumNow

1 month 3 weeks ago
British Dermatology Biologics registry (BADBIR) 18976 #PSO pts had incidence serious infxns (SIE) 28 SEI/1000 Pt-Yrs; higher if they had prior infxn (79/1000 PYs). SIE signif lower w/ RIZankizumab (HR 0.74-.80) vs BROAD, ETN, other standards Rxs. SIE deaths rare (1.81/1000 PYs) https://t.co/GTr3DLCVXs
JAMA Case Quiz - A 57 yoF w/ #RA has a new vesicular rash. 9mos prior ETN change to ADA. Rash (painful, pruritic) starte

Dr. John Cush RheumNow

1 month 3 weeks ago
JAMA Case Quiz - A 57 yoF w/ #RA has a new vesicular rash. 9mos prior ETN change to ADA. Rash (painful, pruritic) started 2 wks ago. Exam: PIP swelling, & ulcerated plaques on neck, chest, & erythroderma on hands, CRP 15.0 mg/L , ESR 111 mm/h. What would you do? order?
Gout: Diagnosis
The diagnosis of gout - labs, imaging and polarized microscopy, created by @MithuRheum for RheumNow.

Dr. John Cush RheumNow

1 month 3 weeks ago
Gout: Diagnosis The diagnosis of gout - labs, imaging and polarized microscopy, created by @MithuRheum for RheumNow. https://t.co/s8gkANFJSB https://t.co/pkUeFLG5if
Interferon-α as an Immunologic Driver of Sjögren's Disease

Using data from a Sjogren's registry, researchers have sh

Dr. John Cush RheumNow

1 month 3 weeks ago
Interferon-α as an Immunologic Driver of Sjögren's Disease Using data from a Sjogren's registry, researchers have shown that IFNα drives Sjögren's disease, and can be elevated a decade before diagnosis. This study assessed the role of type 1 interferon (IFNα) in its onset and https://t.co/Clj9u5COzQ
Future therapies (in development) for gout - the goal is durable crystal depletion.
Created by: Dr. Aravind Palraj @rheu

Dr. John Cush RheumNow

1 month 3 weeks ago
Future therapies (in development) for gout - the goal is durable crystal depletion. Created by: Dr. Aravind Palraj @rheumat_aravind for RheumNow. https://t.co/yeCSAnHiY2 https://t.co/nH8f2Y3hNP
Calcium Pyrophosphate Deposition Dz new terminology from 2026 G-CAN consensus. Preferred:
- acute CPP crystal arthritis

Dr. John Cush RheumNow

1 month 3 weeks ago
Calcium Pyrophosphate Deposition Dz new terminology from 2026 G-CAN consensus. Preferred: - acute CPP crystal arthritis - Chronic CPP crystal arthritis - Chronic CPP crystal arthritis - OA w/ CPP - Chondrocalcinosis (xray) * Pseudogout is obsolete https://t.co/bsztXz9UDs https://t.co/GOey5YmKif
Medscape asked medical authors (panel of experts), including Roach, Epstein, and several literary medical professionals

Dr. John Cush RheumNow

1 month 3 weeks ago
Medscape asked medical authors (panel of experts), including Roach, Epstein, and several literary medical professionals — this question: What’s a book every clinician should read? Here's an interesting read list for some of you! (I loved "Stiff" by Mary Roach; its about https://t.co/L5NSHjPKwA
Social Media (SM) for Health Information by US (sample 7278 adults) - SM use reported by 88% (representing ~ 228 million

Dr. John Cush RheumNow

1 month 3 weeks ago
Social Media (SM) for Health Information by US (sample 7278 adults) - SM use reported by 88% (representing ~ 228 million). ~22% adults made health decisions based on SM, despite almost 78% reporting distrust of SM. Lower SM use in older, rural, less educated. https://t.co/uYYzBvckFu
British Dermatology Biologics registry (BADBIR) 18976 #PSO pts had incidence serious infxns (SIE) 28 SEI/1000 Pt-Yrs; hi

Dr. John Cush RheumNow

1 month 3 weeks ago
British Dermatology Biologics registry (BADBIR) 18976 #PSO pts had incidence serious infxns (SIE) 28 SEI/1000 Pt-Yrs; higher if they had prior infxn (79/1000 PYs). SIE signif lower w/ RIZankizumab (HR 0.74-.80) vs BROAD, ETN, other standards Rxs. SIE deaths rare (1.81/1000 PYs) https://t.co/5HqJ3zpO0g
New, Advanced Therapies in Gout
Dr. Jack Cush reviews the news and journal articles from this past week on RheumNow.com.
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