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A US study shows that nearly two-thirds of the population had suboptimal 5-year sleep duration trajectories with a resultant 29% increase in risk of all-cause mortality.
Schnitzler Syndrome: A Rare Autoinflammatory Disorder
A credible, quick overview
Chronic Urticaria
Monoclonal Gammopath

Dr. John Cush RheumNow

1 year 5 months ago
Schnitzler Syndrome: A Rare Autoinflammatory Disorder A credible, quick overview Chronic Urticaria Monoclonal Gammopathy ( Recurrent Fever Bone & Joint Pain Elevated CRP &ESR https://t.co/boYFFEVwII https://t.co/xKCUZb8o6A
The global biosimilars market size is evaluated at USD $40 billion in 2025 and is expected to hit approximately USD 176

Dr. John Cush RheumNow

1 year 5 months ago
The global biosimilars market size is evaluated at USD $40 billion in 2025 and is expected to hit approximately USD 176 billion by 2034 (a 17.78% increase) https://t.co/U4PbinVN4J https://t.co/SLHynlhJrs
A study from the Lupus Hopkins Cohort shows that systemic lupus erythematosus (SLE) patients with pericarditis are at risk for recurrence, and likely to be younger patients, with uncontrolled disease, and linkage to higher doses of oral prednisone.
Diagnoses via Immune ‘Fingerprints’

Science and researchers at Stanford Medicine have reported the use of Mal-ID (

Dr. John Cush RheumNow

1 year 5 months ago
Diagnoses via Immune ‘Fingerprints’ Science and researchers at Stanford Medicine have reported the use of Mal-ID (machine learning for immunological diagnosis) to analyze B and T cell receptors (BCRs and TCRs) sequences from human blood, showing the ability to predict health… https://t.co/ni09ssCYSv https://t.co/4HWui3XxfE
Postoperative Weight Loss Improves Joint Replacement Survival

A cohort study of shows that postoperative weight loss w

Dr. John Cush RheumNow

1 year 5 months ago
Postoperative Weight Loss Improves Joint Replacement Survival A cohort study of shows that postoperative weight loss with antiobesity medications significantly reduced the risk of 5-year and 10-year revision among patients with obesity undergoing hip or knee replacement.… https://t.co/u04Lc6DTT0 https://t.co/iZhEICFHUd
Cross-trait study of >300K patients’ electronic health records at UCSF and Stanford. Autoimmune conditions associa

Dr. John Cush RheumNow

1 year 5 months ago
Cross-trait study of >300K patients’ electronic health records at UCSF and Stanford. Autoimmune conditions associate with greater Alzheimer’s risk (ORs 1.4–1.7). Women with autoimmune disorders have higher risk than men with autoimmune disorders https://t.co/bwtGhyNBs6 https://t.co/FNUdRNozCw
Cochrane review of TNF inhib. in #JIA shows TNFi efficacy, but uncertainty about LT safety, pain, function, & Dz con

Dr. John Cush RheumNow

1 year 5 months ago
Cochrane review of TNF inhib. in #JIA shows TNFi efficacy, but uncertainty about LT safety, pain, function, & Dz control - esp compared to MTX. 9 studies, 678 JIApts, age 8-15 yrs (80% F), Dz duration 0.8-6.7 yrs. Withdrawls 1% v 3%; Serious AE 6% v 7% (PBO vs TNFi).… https://t.co/twmYfFg702 https://t.co/hG3j4sMPr9
RNA-seq analysis of human chondrocytes (HTC) shows Osteoarthritis has more HTC-1 (w/ more cell apoptosis & PD-1 gen

Dr. John Cush RheumNow

1 year 5 months ago
RNA-seq analysis of human chondrocytes (HTC) shows Osteoarthritis has more HTC-1 (w/ more cell apoptosis & PD-1 genes) & proliferate fibrochondrocytes (ProFC2) w/ heightened inflammatory response, & increased cytokine signalling https://t.co/FZ72CnWk20 https://t.co/sx4NB2C8h3
JAMA Dermatology reports a retrospective cohort study from Johns Hopkins reviewing mimic of dermatomyositis (DM), suggesting that DM and especially clinically amyopathic DM (CADM) are commonly and initially misdiagnosed as inflammatory skin disease (ISD).The study was undertaken to evaluate misdiagnosis patterns and the clinical implications of those with DM and CADM.
A study from the FDA's adverse event reporting system (FAERS or Medwatch) database identified cases of drug induced systemic lupus erythematosus (SLE) in patients receiving tumor necrosis factor-α (TNF-α) inhibitors - a paradoxical reaction to common antiinflammatory biologic agents.
Peking Univ long term F/U of Knee replacement (TKA) in 226 patients (246 knees) shows prosthesis survival rates of 93.6%

Dr. John Cush RheumNow

1 year 5 months ago
Peking Univ long term F/U of Knee replacement (TKA) in 226 patients (246 knees) shows prosthesis survival rates of 93.6%, 92.4%, 89.8%, and 71.8% at 10, 15, 20, and 25 years post-TKA, respectively. 20yr function somewhat less than 10yr, but still much better than preop… https://t.co/gJbedIEr91 https://t.co/q799oV8TNm
Do infections lead to Kawasaki Dz (KD)? Swedish registry study of 1774 KD vs 17 731 controls. +Hx of Infx incr risk o

Dr. John Cush RheumNow

1 year 5 months ago
Do infections lead to Kawasaki Dz (KD)? Swedish registry study of 1774 KD vs 17 731 controls. +Hx of Infx incr risk of KD (OR 2.3; 2.0 to 2.5) - mostly Resp, skin, GU & GI Infx. Infxns usually clustered before KD Dx (OR 5.1 15–28d; OR 1.3 6-12 mos prior KD. More infx = more KD… https://t.co/V9zbcmJdKv https://t.co/Evl3rtCxUO
Bubble Trouble - When Bullous Lupus Bursts onto the SLE Scene

Presentation by Dr. Alana Haussmann at the Rheumatology

Dr. John Cush RheumNow

1 year 5 months ago
Bubble Trouble - When Bullous Lupus Bursts onto the SLE Scene Presentation by Dr. Alana Haussmann at the Rheumatology Winter Clinical Symposia - Feb 2025 https://t.co/bkQSq51BEo https://t.co/DLBs3uIyH7
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