Selective mutation of Traf1/cIAP2 (V196) interaction attenuates inflammatory responses that may contribute to rheumatoid arthritis activity. THis may lead to a new class of therapies for RA https://t.co/kYqAqGsSEA https://t.co/JWUN6iTvxa

• Breakthrough study discovers genetic mutation could be basis for novel treatmen…

I ALWAYS recommend paraffin wax baths for stiffness, RA, OA, PSS, etc. Here are some instructions for home use https://t.co/CTI4K2kHf9 https://t.co/i0kO99vdYc

• Paraffin Wax Baths; Types, Methods, Procedures, Uses - illnesshacker (2025)

AbbVie Receives Positive CHMP Opinion for Upadacitinib (RINVOQ®) for the Treatment of Adults with Giant Cell Arteritis https://t.co/WP8JGpHc6p https://t.co/x9m870mCJ4

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UK MRCP exam makeup: Cardio 15% Pharm 15% Resp 10% GI 10% Neuro 10% ID 8% Endo 8% RHEUM 6% Heme 5% Renal 5% Derm 4% Eye 2% Psych 2% https://t.co/WG7X3B8a0Y https://t.co/9VF5LkLJjs

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Cochrane review of TNF inhib. in #JIA shows TNFi efficacy, but uncertainty about LT safety, pain, function, & Dz control - esp compared to MTX. 9 studies, 678 JIApts, age 8-15 yrs (80% F), Dz duration 0.8-6.7 yrs. Withdrawls 1% v 3%; Serious AE 6% v 7% (PBO vs TNFi).… https://t.co/i35m5uzG1m https://t.co/VzJN9PmmMh

"Never take the advice of someone who has not had your kind of trouble" - Sidney J. Harris https://t.co/xdB6u6OiPq

Ankle Fusion or Total Replacement? In a large study of British patients needing surgical treatment for advanced arthritis in the ankle, fusion appeared to be a better option than total ankle replacement. https://t.co/ZFbd2VinpP https://t.co/QCqMkxNLoQ

• Ankle Fusion or Total Replacement? | RheumNow

Schnitzler Syndrome: A Rare Autoinflammatory Disorder A credible, quick overview Chronic Urticaria Monoclonal Gammopathy ( Recurrent Fever Bone & Joint Pain Elevated CRP &ESR https://t.co/sQ22t8Z46m https://t.co/nJOVCghoFa

• Schnitzler Syndrome: A Rare Autoinflammatory Disorder

Diagnoses via Immune ‘Fingerprints’ Science and researchers at Stanford Medicine have reported the use of Mal-ID (machine learning for immunological diagnosis) to analyze B and T cell receptors (BCRs and TCRs) sequences from human blood, showing the ability to predict health… https://t.co/nqyf4iaD10 https://t.co/wt5V6uxLYf

JAMA Case: A Woman With Painful Digital Ulcers - What would you order next? - chest CT w/ myositis-specific autoAb panel - dsDNA - SCL-70 & Centromere Abs - muscle biopsy https://t.co/t0WCIMtZg2 https://t.co/M1jBhnclLl

• A Woman With Painful Digital Ulcers

Misdiagnosis of Dermatomyositis JAMA Dermatology reports a retrospective cohort study from Johns Hopkins reviewing mimic of dermatomyositis (DM), suggesting that DM and especially clinically amyopathic DM (CADM) are commonly and initially misdiagnosed as inflammatory skin… https://t.co/2SbGxxcPLm https://t.co/TtoxFIXg3Q

TNF Inhibitor Drug-Induced Lupus A study from the FDA's adverse event reporting system (FAERS or Medwatch) database identified cases of drug induced systemic lupus erythematosus (SLE) in patients receiving tumor necrosis factor-α (TNF-α) inhibitors - a paradoxical reaction to… https://t.co/LYq0qxDtp3 https://t.co/vRYrBAIMEA