VERY exciting SLE update from Fava et al. Machine learning used to generate urinary protein panel predictive of intra-renal inflammation BETTER than serum biomarkers C3, C4, dsDNA Also monitoring tool for renal response. Outstanding. @RheumNow #ACRbest #ACR24 https://t.co/YXgKrSU4UQ

• https://x.com/Dr_Brian_MD/status/1858272797983977838/photo/1
• https://x.com/Dr_Brian_MD/status/1858272797983977838/photo/1

To stop tsDMARD / bDMARD To improve #COVIDVACCINE response in those w several previous #COVID19 #vaccinations is NOT necessary This will change my practice! #ACR24 @RheumNow @ACRheum https://t.co/WXeqMOEfuA

• https://twitter.com/healiorheum/status/1858268880310874586

What a result!!! Crowed split 49% against and 51% for MCTD as a unique disease entity Given pre-debate poll of >70% for MCTD, looks like an overall win for the “NOT” group Fantastic session from all the presenters @RheumNow #ACR24 https://t.co/GgTVQ1VNWP

• https://x.com/Dr_Brian_MD/status/1858266822073581805/photo/1

Super helpful results from COVER study, holding JAK or IL17 for COVID boosters Antibody titers went up regardless of holding Holding caused flares (14-25% increase!) Pretty clear message; continue JAK / IL17 #ACR24 @RheumNow Abstr#1718 #ACRbest https://t.co/Mf89dWrRWz

• https://x.com/EBRheum/status/1858267620316688737/photo/1

Would be helpful for us (and pts) to better understand rimmunotherapy agent specific risk on subsequent GCA/PMR AFTRER propensity matching of >7k pt on combo nivolumab/ipilimumab compared to pembrolizumab: - PMR RR 3.8x N/I vs. P - no diff in GCA risk @RheumNow #ACR24 https://t.co/IF4Gh7Cumd

• https://x.com/Dr_Brian_MD/status/1858268380714664309/photo/1

🔶Clinical Year in Review #ACR24 🔶 Talk By @MHPillingerMD • Review some of the most impactful studies in Rheumatology from the past year! #RheumTwitter #Rheumatology https://t.co/1ULDB2l4gX

• https://x.com/MithuRheum/status/1858157622219641261/photo/1

The anti-MCTD group strikes back Of cohort of over 1,000 RNP+ pt, only 17 clinically diagnosed with MCTD Majority of patients, despite potential overlap, treated for other primary rheum dz @RheumNow #ACR24 https://t.co/vkQ6UPs34y

• https://x.com/Dr_Brian_MD/status/1858261782160351458/photo/1

Older RA patients in RISE with high disease activity show a higher incidence of hip and major osteoporotic fractures. Practice T2T and monitor bone health closely! #ACR24 @RheumNow ABST#1748 https://t.co/7MCAIrfXhp

• https://x.com/JihaRheum/status/1858263593927778331/photo/1

Phase 2 RCT of MK2 inhibitor did not show clinical efficacy at week 12 in active AS pts compared to PBO. There are still unmet needs for additional therapeutics in pts with AS that not respond to current therapies. Abst#1760 #ACR24 @RheumNow https://t.co/cXv8HYr0Xr

• https://x.com/AdelaCastro222/status/1858263006217400826/photo/1
• https://x.com/AdelaCastro222/status/1858263006217400826/photo/1

Comparison of infection risk across b/tsDMARDs in IA in real-world study Treatment with ➡️Rituximab ➡️JAKi ➡️Anti-IL6 assoc with ⬆️⬆️ risk of severe infection compared to TNFi A reminder to consider comorbidities & infection risk in selecting b/tsDMARDs Ab1716 #ACR24 @RheumNow

RCTs are the gold standard in drug research, but rising placebo (PBO) response rates with global recruitment could distort treatment effects. Limited access to care in less affluent countries may be a factor. #ACR24 @RheumNow ABST#1746 https://t.co/fVeNcw5qwO

• https://x.com/JihaRheum/status/1858256799196971041/photo/1

SURPASS trial of bio naïve axSpA at risk of radiographic progression: 1. Presence of syndesmophytes 2. Higher CRP levels 3. Higher ASDAS 4. Higher spinal MRI BME scores Were predictors of spinal progression independent of ttnt Abst#1759 #ACR24 @RheumNow https://t.co/QC9FMPufPY

• https://x.com/AdelaCastro222/status/1858257553966141559/photo/1
• https://x.com/AdelaCastro222/status/1858257553966141559/photo/1

How does #race & #ethnicity impact mortality in RA? Study in CDC national mortality database ➡️RA mortality differed by race & ethnicity ➡️Highest premature mortality in Native Americans Findings may be used to inform resource allocation & management Ab1747 #ACR24 @RheumNow