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Results from SELECT-GCA➡️UPA 15mg + 26W GC taper demonstrates superior efficacy & reduced GC use vs PBO + 52W

Mrinalini Dey DrMiniDey

1 year 9 months ago

Results from SELECT-GCA ➡️UPA 15mg + 26W GC taper demonstrates superior efficacy & reduced GC use vs PBO + 52W GC taper ➡️No new safety signals Is UPA the new kid on the block in #GCA? Ab0770 #ACRBest #ACR24 @RheumNow https://t.co/pHzozYiid5

#obesity causes a lot of diseases including #arthritis. How?
⬆️ IL-6
⬆️ leptin
⬆️ TNF-a
@RheumNow #ACR24
@

sheila RHEUMarampa

1 year 9 months ago
#obesity causes a lot of diseases including #arthritis. How? ⬆️ IL-6 ⬆️ leptin ⬆️ TNF-a @RheumNow #ACR24 @rheumarhyme https://t.co/qeqTZUOEZy
The Plants for Joints RA continuation made it to #ACR24!

whole-food plant-based diet, exercise, sleep/stress Rx
(added

David Liew drdavidliew

1 year 9 months ago
The Plants for Joints RA continuation made it to #ACR24! whole-food plant-based diet, exercise, sleep/stress Rx (added on to usual RA care i.e. DMARDs) Gains made during program were sustained, can't undersell lifestyle as part of the overall picture! #ACR24 ABST0530 @RheumNow https://t.co/XSLIwYitpH https://t.co/RfiTX8Z6ff
The TAPIR Trial on GPA shows higher (15.5%) relapse in the 0 mg prednisone arm vs. 4.2% in the 5 mg arm (OR 4.22), but d

Antoni Chan MD (Prof) synovialjoints

1 year 9 months ago
The TAPIR Trial on GPA shows higher (15.5%) relapse in the 0 mg prednisone arm vs. 4.2% in the 5 mg arm (OR 4.22), but does not impact PROs. Key finding: benefit of 5 mg/day seen only in non-rituximab regimens (20% vs. 2.6%, OR 9.50). Abstr#0774 Plenary 1 @RheumNow #ACR24… https://t.co/5DjW5Zwh0J https://t.co/UnsVPzJfs6
Want to lose weight naturally? Eat your veggies and protein first, and the carbs last— this reduces the post-prandial

TheDaoIndex KDAO2011

1 year 9 months ago
Want to lose weight naturally? Eat your veggies and protein first, and the carbs last— this reduces the post-prandial glucose, insulin and raises GLP-1 - Dr Aronne #ACR24 @RheumNow https://t.co/cRVRzRTljT
SELECT-GCA: Upa in GCAMerkelUpa 15 mg v 7.5 v PBO w slower GC taper70% new onset, 30% relapse. Few prev on IL6Primar

Eric Dein ericdeinmd

1 year 9 months ago

SELECT-GCA: Upa in GCA Merkel Upa 15 mg v 7.5 v PBO w slower GC taper 70% new onset, 30% relapse. Few prev on IL6 Primary endpt: sustained remission at w52- UPA 15 mg beats PBO (p=0.0019) 34% relapse in UPA vs 60% PBO Less steroids, longer time to flare @RheumNow #ACR24 #ACRBest https://t.co/1OV2889Ny0

Great summary of treatment choices in PsA:
1. Identify domain involved
2. Identify comorbidities/pt preferences
3. Still

Adela Castro AdelaCastro222

1 year 9 months ago
Great summary of treatment choices in PsA: 1. Identify domain involved 2. Identify comorbidities/pt preferences 3. Still unmet needs for ttx in inflammatory eye disease #ACR24 @rheumnow https://t.co/1WMnkDYvip
Upadacitinib in GCA. Merkel et al. SELECT-GCA study. Sustained remission week 52 Upa (+26 week steroid) 46% vs PBO (+52

Richard Conway RichardPAConway

1 year 9 months ago
Upadacitinib in GCA. Merkel et al. SELECT-GCA study. Sustained remission week 52 Upa (+26 week steroid) 46% vs PBO (+52 week steroid) 29%. Reduced flare rates with UPA (see picture). Similar to GiACTA results. @RheumNow #ACR24 Abstr#0770 https://t.co/fr75XK21L1 https://t.co/Hhax7po7vV
Managing health conditions is rapidly evolving as patients increasingly turn to online resources for answers—over 65% search for health-related questions online. Our study analyzed Google search trends for rheumatic disease topics, offering a fascinating glimpse into how online search behavior can reveal patient needs and experiences. This approach, known as "infodemiology," tracks real-time Google Trends data to understand symptom- and
What agent to pick after a TNFi has failed: another TNFi or a non-TNFi?
Would a TNFi drug conc help (i.e. if low, increa

David Liew drdavidliew

1 year 9 months ago
What agent to pick after a TNFi has failed: another TNFi or a non-TNFi? Would a TNFi drug conc help (i.e. if low, increased clearance due to secondary failure)? In this RCT @maartenskliniek, this TDM approach was no better than random selection. Argh #ACR24 ABST0533 @RheumNow https://t.co/3h8o4ARZG3
Seronegative RA: sometimes there's an assumption that they'll eventually get a 'real' diagnosis

at @MayoClinic, 85% of

David Liew drdavidliew

1 year 9 months ago
Seronegative RA: sometimes there's an assumption that they'll eventually get a 'real' diagnosis at @MayoClinic, 85% of patients diagnosed with seronegative RA kept their diagnosis at 10 years. Usually, seroneg RA means seroneg RA! #ACR24 @MyasoedovaElena ABST0458 @RheumNow https://t.co/hErZVfs08k
❓What factors influence patient participation in rheumatology #ClinicalTrials?

📌 Come to poster 0366 to find out!

Mrinalini Dey DrMiniDey

1 year 9 months ago
❓What factors influence patient participation in rheumatology #ClinicalTrials? 📌 Come to poster 0366 to find out! 👨🏻‍⚕️ @KKouranloo & @chriswincup report results from a UK study, showing marked differences by ethnicity & RMD @RheumNow Ab0366 #ACR24 https://t.co/kAqGJmNiPt
Real-world data from @k_lauper's Jak-pot study (>9000 RA pt) on how quickly b/tsDMARDs work:
JAKi, TNFi quicker than

David Liew drdavidliew

1 year 9 months ago
Real-world data from @k_lauper's Jak-pot study (>9000 RA pt) on how quickly b/tsDMARDs work: JAKi, TNFi quicker than tocilizumab, abatacept Even though they all get to a similar place eventually, some get there quicker (but worth any safety tradeoffs?) #ACR24 ABST0501 @RheumNow https://t.co/YVpTBMe3gi
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